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MitraClip for severe symptomatic mitral regurgitation in patients at high surgical risk
ConclusionBased on high risk MC studies and high risk MVS data predominantly from STS database, patients with severe MR who are at HSR can be effectively treated with MC or MVS. MC can be safely implanted in high risk patients with relatively low mortality and stroke risk. © 2014 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - July 2, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Femi Philip, Ganesh Athappan, E. Murat Tuzcu, Lars G. Svensson, Samir R. Kapadia Tags: Valvular and Structural Heart Diseases Source Type: research

Clinical implications for diffusion‐weighted MRI brain lesions associated with transcatheter aortic valve replacement
Transcatheter aortic valve replacement (TAVR) is increasingly used to treat patients with aortic stenosis deemed high or extreme surgical risk candidates. Despite improved survival and quality of life following the procedure, TAVR is not without its complications. Stroke is a major source of morbidity and mortality in patients undergoing the procedure, with rates similar to and often higher than those associated with surgery. Most studies show a consistent link between TAVR and embolic lesions visualized on diffusion‐weighted magnetic resonance imaging. The question of whether these lesions lead to long‐term cognitive ...
Source: Catheterization and Cardiovascular Interventions - April 9, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Stephanie M. Meller, Andreas Baumbach, Adam M. Brickman, Alexandra J. Lansky Tags: Valvular and Structural Heart Diseases Source Type: research

Cerebral Events and Protection During Transcatheter Aortic Valve Replacement
Abstract Stroke has emerged as one of the most concerning complications following transcatheter aortic valve replacement (TAVR); associated with high morbidity and mortality. We discuss the potential mechanisms of stroke following TAVR, as well as the newly developed embolic protection devices aimed to reduce the risk of stroke. © 2014 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - February 19, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Melanie Freeman, Marco Barbanti, David A. Wood, Jian Ye, John G. Webb Tags: Core Curriculum Source Type: research

Impact of pre ‐existing or new‐onset atrial fibrillation on 30‐day clinical outcomes following Transcatheter Aortic Valve Replacement: Results From The BRAVO 3 Randomized Trial
Conclusions: Prior or new‐onset AF within 30 days of transfemoral TAVR is noted in more than one‐third of patients. Despite greater baseline comorbidities than non‐AF patients, AF was not associated with greater risk of adjusted 30‐day outcomes. In the BRAVO 3 trial, early outcomes were similar regardless of anticoagulant strategy in each group. This article is protected by copyright. All rights reserved.
Source: Catheterization and Cardiovascular Interventions - May 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Christian Hengstenberg, Jaya Chandrasekhar, Samantha Sartori, Thierry Lefevre, Ghada Mikhail, Nicolas Meneveau, Christophe Tron, Raban Jeger, Christian Kupatt, Birgit Vogel, Serdar Farhan, Sabato Sorrentino, Madhav Sharma, Clayton Snyder, Oliver Husser, P Tags: VSD ‐ Valvular and Structural Heart Diseases Source Type: research

Outcomes of intermediate ‐risk patients treated with transcatheter and surgical aortic valve replacement in the Veterans Affairs Healthcare System: A single center 20‐year experience
ConclusionsAdoption of TAVR as the preferred treatment modality in intermediate‐risk patients may result in significant improvements in morbidity and mortality.
Source: Catheterization and Cardiovascular Interventions - January 9, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Santiago Garcia, Rosemary Kelly, Mackenzie Mbai, Sergey Gurevich, Brett Oestreich, Demetris Yannopoulos, Selcuk Adabag Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

Transcatheter aortic valve implantation without balloon pre‐dilation: A single‐center pilot experience
Conclusions: These results suggest that direct CoreValve implantation in patients with severe aortic stenosis is feasible and may lead to hemodynamic and clinical improvement in patients who are poor candidates for aortic valve surgery, pending confirmation in larger series with longer follow‐up. © 2013 Wiley‐Liss, Inc.
Source: Catheterization and Cardiovascular Interventions - April 1, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Oscar A Mendiz, Hugo Fraguas, Gustavo A Lev, Leon R Valdivieso, Roberto R Favaloro Tags: Original Study Source Type: research

Transcatheter aortic valve implantation without balloon predilation: A single‐center pilot experience
ConclusionsThese results suggest that direct CoreValve implantation in patients with severe aortic stenosis is feasible and may lead to hemodynamic and clinical improvement in patients who are poor candidates for aortic valve surgery, pending confirmation in larger series with longer follow‐up. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - April 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Oscar A. Mendiz, Hugo Fraguas, Gustavo A. Lev, Leon R. Valdivieso, Roberto R. Favaloro Tags: Valvular and Structural Heart Diseases Source Type: research

Single center TAVR experience with a focus on the prevention and management of catastrophic complications
Conclusions: TAVR can be accomplished with excellent safety in a tertiary center with a well‐developed infrastructure for the management of serious complications. The data presented here provide support for TAVR as an important treatment option, and results from randomized trials of patients with lower surgical risk are eagerly awaited. © 2014 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - January 9, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Samir R. Kapadia, Lars G. Svensson, Eric Roselli, Paul Schoenhagen, Zoran Popovic, Andrej Alfirevic, Benico Barzilai, Amar Krishnaswamy, William Stewart, Anand Mehta, Kanhaiya lal Poddar, Akhil Parashar, Dhruv Modi, Alper Ozkan, Umesh Khot, Bruce W. Lytle Tags: Original Study Source Type: research

Feasibility and safety of transfemoral implantation of Edwards SAPIEN XT prosthesis without balloon valvuloplasty in severe stenosis of native aortic valve
ConclusionsDirect implantation of Edwards SAPIEN XT without prior BV in selected cases is feasible and safe. The number of patients in whom this technique would be applicable, and their impact on reducing complications has to be determined. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - November 8, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Eulogio García, Patricia Martín, Rosana Hernández, Victor Rodríguez, Abelardo Fernández, Vasco Gama, Carlos Almería, Carlos Macaya Tags: Valvular and Structural Heart Diseases Source Type: research

Prevalence and predictors of carotid artery stenosis in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation
Conclusions: The prevalence of CAS in patients undergoing TAVI is high, exceeding that observed in patients undergoing catheterization for coronary indications. The impact of CAS on clinical outcomes following TAVI merits further research. © 2014 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - June 27, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Arie Steinvil, Eran Leshem‐Rubinow, Yigal Abramowitz, Yacov Shacham, Yaron Arbel, Shmuel Banai, Natan M. Bornstein, Ariel Finkelstein, Amir Halkin Tags: Original Studies Source Type: research

A novel approach to extraction of a large thrombus on the intraventricular guide‐wire during transcatheter aortic valve replacement
We report a case where a large guide‐wire thrombus identified during TAVR was successfully removed using a novel approach, preventing a potentially major stroke in this high‐risk patient. © 2015 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - September 2, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Thomas Chin, Padmanabhan Priyesh, Ashequl M. Islam Tags: Valvular and Structural Heart Diseases Source Type: research

Efficacy and safety of transcatheter aortic valve replacement in intermediate surgical risk patients: A systematic review and meta‐analysis
ConclusionsIn this meta‐analysis we found that TAVR may be an acceptable alternative to SAVR in patients with intermediate risk for surgery. However, we must await evidence from the current large randomized trials before widespread adoption of this procedure is undertaken. © 2016 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - March 4, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Abdur Rahman Khan, Sobia Khan, Haris Riaz, Faraz Khan Luni, Herman Simo, Aref Bin Abdulhak, Chirag Bavishi, Michael Flaherty Tags: Valvular and Structural Heart Diseases Source Type: research

A novel approach to extraction of a large thrombus on the intraventricular guide ‐wire during transcatheter aortic valve replacement
We report a case where a large guide‐wire thrombus identified during TAVR was successfully removed using a novel approach, preventing a potentially major stroke in this high‐risk patient. © 2015 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - September 1, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Thomas Chin, Padmanabhan Priyesh, Ashequl M. Islam Tags: Valvular and Structural Heart Diseases Source Type: research

Clinical and procedural outcomes with the SAPIEN 3 versus the SAPIEN XT prosthetic valves in transcatheter aortic valve replacement: A systematic review and meta ‐analysis
ConclusionsPatients receiving the S3V had lower risk of PVL, MVC, bleeding, mortality, and stroke. PPI was somewhat higher in the S3V group. S3V implantation was faster and used less contrast.
Source: Catheterization and Cardiovascular Interventions - October 25, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Ramyashree Tummala, Kinjal Banerjee, Kesavan Sankaramangalam, Stephanie Mick, Amar Krishnaswamy, Jonathon White, Maan Fares, Anand Mehta, Zoran Popovic, Lars G. Svensson, Samir R. Kapadia Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

Comparison of single versus dual antiplatelet therapy after TAVR: A systematic review and meta ‐analysis
ConclusionIn this small meta‐analysis of DAPT versus SAPT after TAVR, DAPT did not prevent stroke, myocardial infarction or death while the risk of bleeding was higher. Results from ongoing trials are awaited to determine the best anti‐thrombotic approach after TAVR.
Source: Catheterization and Cardiovascular Interventions - March 8, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Hitesh Raheja, Aakash Garg, Sunny Goel, Kinjal Banerjee, Gerald Hollander, Jacob Shani, Stephanie Mick, Jonathan White, Amar Krishnaswamy, Samir Kapadia Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

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