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Genetic determinants and stroke in children with sickle cell disease.
CONCLUSION: There is a high incidence of stroke in male children and in children with SCA. Coexistence with α-thal and haplotypes of the beta globin chain cluster did not show any significant association with stroke. The heterogeneity between previously evaluated populations, the non-reproducibility between studies, and the need to identify factors associated with stroke in patients with SCA indicate the necessity of conducting further research to demonstrate the relevance of genetic factors in stroke related to SCD. PMID: 27268459 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - June 3, 2016 Category: Pediatrics Authors: Rodrigues DO, Ribeiro LC, Sudário LC, Teixeira MT, Martins ML, Pittella AM, Junior IO Tags: J Pediatr (Rio J) Source Type: research

Assessment of acute motor deficit in the pediatric emergency room.
CONCLUSIONS: The clinical skills to obtain a complete history and to perform a detailed physical examination are emphasized. An organized, logical, and stepwise diagnostic and therapeutic management is essential to eventually restore patient's well-being and full health. PMID: 28756061 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - July 26, 2017 Category: Pediatrics Authors: Vasconcelos MM, Vasconcelos LGA, Brito AR Tags: J Pediatr (Rio J) Source Type: research

Clinical and hematological profile in a newborn cohort with hemoglobin SC.
CONCLUSIONS: Clinical severity is variable in SC hemoglobinopathy. Several children have severe manifestations similar to those with SS disease. PMID: 29195085 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - November 28, 2017 Category: Pediatrics Authors: Rezende PV, Santos MV, Campos GF, Vieira LLM, Souza MB, Belisário AR, Silva CM, Viana MB Tags: J Pediatr (Rio J) Source Type: research

Lifestyle, inadequate environments in childhood and their effects on adult cardiovascular health
CONCLUSIONS: There are direct relationships between lifestyle and inadequate environments in childhood and cardiovascular effects, although the observed associations showed divergences in terms of results and interpretation. In spite of these, it is recommended to encourage healthy lifestyles and protection against childhood injuries, as habit formation occurs at this age, and its relationship with CVRF since childhood has already been well established. On the other hand, the format and intensity of the stimulus must respect the social, cultural and psychological aspects of each population, aiming to obtain the best and mo...
Source: Jornal de Pediatria - November 21, 2021 Category: Pediatrics Authors: Isabela de Carlos Back Nelson Filice de Barros Bruno Caramelli Source Type: research