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Source: Neurology
Procedure: Gastroschisis Repair
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Total 36 results found since Jan 2013.
Teaching NeuroImages: Abnormal cervical and cerebral vasculature in 22q11 deletion syndrome
A 12-day-old girl with a postnatal microarray diagnosis of 22q11.2 deletion syndrome was transferred for surgical repair of truncus arteriosus. Neurologic examination at the time of transfer was unremarkable. Brain MRI on day of life 9 demonstrated an absent left internal carotid flow void. Magnetic resonance angiography of the head (figure, A) and neck (figure, B) was subsequently obtained prior to cardiac repair. Patients with 22q11 deletion syndromes may have abnormal cervical vessel development.1 Children with congenital heart disease have an elevated stroke risk, particularly for periprocedural stroke.2 Understanding ...
Source: Neurology - July 3, 2017 Category: Neurology Authors: Mithal, D. S., Kurz, J. E. Tags: All Cerebrovascular disease/Stroke, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke, All Genetics RESIDENT AND FELLOW SECTION Source Type: research
Retrospective analysis of Spinal Cord Infarction after Aortic Repair (P6.300)
Conclusions:The rate of spinal cord infarction after aortic repair is low overall, but is higher after repair of a ruptured aortic aneurysm or dissection.Study Supported by:Dr. Gialdini is supported by the Feil Family Foundation.Dr. Kamel is supported by NIH grants K23NS082367 and R01NS097443 as well as the Michael Goldberg Research Fund.Disclosure: Dr. Gialdini has nothing to disclose. Dr. Merkler has nothing to disclose. Dr. Parikh has nothing to disclose. Dr. Lerario has nothing to disclose. Dr. Chatterjee has nothing to disclose. Dr. Kamel has received personal compensation for activities with Genentech as a speaker. D...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Gialdini, G., Merkler, A., Parikh, N., Lerario, M., Chatterjee, A., Kamel, H. Tags: Cardiovascular Issues in Ischemic Stroke Source Type: research
A Multicenter Phase II Randomized Trial of a HIF-Prolyl Hydroxylase Inhibitor for Neuroprotection in High Risk Thoracic Aortic Repair (S7.008)
Conclusions: Perioperative GSK1278863 was associated with more clinical events and SAEs but this is potentially confounded by imbalanced surgical risk in this small study. Overall, neurologic complications were common in this high risk population and additional studies of neuroprotection are needed.Disclosure: Dr. Messe has received personal compensation for activities with GlaxoSmithKline as a consultant. Dr. Messe has received research support from WL Gore and GlaxoSmithKline. Dr. Demopoulos has received personal compensation for activities with GlaxoSmithKline as an employer. Dr. Demopoulos holds stock in GlaxoSmithKlin...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Messe, S., Demopoulos, L., Haws, T., Khonezhad, A., Leshnower, B., Coselli, J., Appoo, J., Hughes, G., Reece, T., Brinster, D., Kasner, S., Kern, J., Desai, N., Ballard, V., Fang, F., Lepore, J., Bavaria, J. Tags: Stroke Clinical Trials Source Type: research
Radiographic and Symptomatic Brain Embolism in Cardiac Interventions: A Systematic Review and Pooled Analysis (P2.292)
Conclusions: Most radiographic infarcts during CABG, and cardiac catheterization remained silent. It appears that AVR might have both higher rate of radiographic infarct but also higher proportions being symptomatic.Disclosure: Dr. Cho has nothing to disclose. Dr. Deshpande has nothing to disclose. Dr. Pasupuleti has nothing to disclose. Dr. Diaz has nothing to disclose. Dr. Uchino has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Cho, S., Deshpande, A., Pasupuleti, V., Diaz, A., Uchino, K. Tags: Acute Endovascular Therapy: Other Considerations Source Type: research
Subarachnoid Hemorrhage with and without Concomitant Sickle Cell Disease, a Comparison Using the Nationwide Inpatient Sample (S4.004)
Conclusions: Based on these data, 2 out of every 1000 cases of SAH in the United States, will be related to SCD. SAH occurs at a much younger age in patients with SCD. Prognosis in patients with SAH related to SCD may be better than in non-SCD patients.Disclosure: Dr. Al Zahmi has nothing to disclose. Dr. Conners has nothing to disclose. Dr. Cutting has nothing to disclose. Dr. Cherian has nothing to disclose. Dr. Song has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Garg has received research support from AHA and RTSC. Dr. Ouyang has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Al Zahmi, F., Conners, J., Cutting, S., Cherian, L., Song, S., Lee, V., Garg, R., Ouyang, B. Tags: Health Disparities and Sex Differences in Stroke Source Type: research
Effect of Rehabilitation on Oligodendrocyte Progenitor Cells in a Mouse Model of White Matter Stroke (P5.224)
Conclusions: Rehabilitation with skilled reach after WMS in this mouse model potentiates two critical components of white matter repair: the number of OPCs, as well as their ability to mature. Disclosure: Dr. Borders has nothing to disclose. Dr. Ng has nothing to disclose. Dr. S. Thomas Carmichael has received personal compensation in an editorial capacity for Neurorehabiliation and Neural Repair.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Borders, C., Ng, K., Carmichael, S. Tags: Cerebrovascular Disease: Animal Models and In Vitro Models Source Type: research
Walking Quality During Inpatient Stroke Rehabilitation Assessed by Wireless Sensing (P5.176)
CONCLUSIONS: The laboratory-quality gait metrics calculated by our wireless sensor system were sensitive to functional improvements during a period of known clinical recovery. Commercial sensor systems, for which steps counts are inaccurate at the slow speeds typical of hemi-paretic walking, have difficulty producing outcomes related to motor control in persons disabled by neurologic disease. Measurement of the quantity and quality of movements performed during daily activities enables clinicians and researchers to supervise gait training and skills practice during rehabilitation.Disclosure: Dr. Dorsch has nothing to discl...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Dorsch, A., Thomas, S., Dobkin, B. Tags: Neuro-rehabilitation: Stroke Source Type: research
Loading doses of aspirin and clopidogrel prior to Enterprise stent-assisted repair of intracranial aneurysm-a pilot study (P3.117)
Conclusions: Loading dose of antiplatelet in Enterprise stent-assisted repair of intracranial aneurysm is not only safe and feasible but associated with good clinical outcome. Therefore, loading doses antiplatelets is an alternative option for patients who are candidates for stent-assisted repair of intracranial aneurysm.Disclosure: Dr. Lodi has nothing to disclose. Dr. Reddy has nothing to disclose. Dr. Devasenapathy has nothing to disclose. Dr. Shehadeh has nothing to disclose. Dr. Hourini has nothing to disclose. Dr. Chou has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Lodi, Y., Reddy, V., Devasenapathy, A., Shehadeh, K., Hourini, A., Chou, C.-A. Tags: Cerebrovascular Disease and Interventional Neurology: Subarachnoid Hemorrhage and Miscellany Source Type: research
Low fixed dose of IV heparin as adjunct to internal carotid artery angioplasty and stent placement in patients with recent ischemic symptoms: A prospective protocol (P2.263)
CONCLUSION: Fixed low dose intravenous heparin as adjunct to CAS in patients with carotid artery stenosis and recent ischemic symptoms is associated with acceptable rates of adverse events and low rates of bleeding complications.Disclosure: Dr. Suri has nothing to disclose. Dr. Jahangir has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Suri, M., Jahangir, N., Qureshi, M., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Carotid Disease and IMT Source Type: research
Metabolomic analysis of PFO-related stroke shows immediate and persistent decrease of homocysteine post PFO closure (P2.277)
Conclusion We found PFO closure to lower HYC immediately in left atrial (arterial) blood, and this effect persists in peripheral venous circulation at 3 months post procedure. Since high level of HYC is independently associated with stroke and heart disease, our results suggest that mechanical PFO repair may improve circulatory profile of PFO stroke patients. Studies in a larger patient cohort and validation of other important metabolites are ongoing.Disclosure: Dr. Deng has nothing to disclose. Dr. Beecher has nothing to disclose. Dr. Burant has nothing to disclose. Dr. Lopez has nothing to disclose. Dr. De Jong has nothi...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Deng, W., Beecher, C., Burant, C., Lopez, M., De Jong, F., Palacios, I., Inglessis, I., Silverman, S., Feeney, K., Elia, M., Wickham, T., McMullin, D., Dec, G. W., Buonanno, F., Lo, E., Ning, M. Tags: Cerebrovascular Disease and Interventional Neurology: PFO and Other Cardiac Disease Source Type: research
Should TCDs be routinely used for evaluating intracranial circulation for screening high risk patients prior to cardiac surgery? (P2.280)
CONCLUSIONS: Our case elucidates the possibility of a hypoperfusion stroke related to left vertebral dominantly supplying intracranial circulation in presence of bilateral significant carotid stenosis. Due to lack of previous cardio/cerebrovascular events, his carotid stenosis was deemed asymptomatic prior to cardiac surgery. We propose that intracranial collateral flow should be investigated via TCD in patients with bilateral carotid stenosis undergoing procedures with high stroke risk to assess safety and efficacy of carotid revascularization in this small but significant subset. Additional studies like acetazolamide wit...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Vu, Q., Bishop, L., Edwards, M., Tegeler, C., Sarwal, A. Tags: Cerebrovascular Disease and Interventional Neurology: PFO and Other Cardiac Disease Source Type: research
Electrical Stimulation of Neural Stem Cells Improves Stroke Recovery (P1.005)
Conclusions: Our results show that electrically preconditioned NSCs enhance stroke recovery. Gene expression of the thrombospondins (a family of matricellular proteins thought to be involved with angiogenesis and inflammation) and VEGF (proteins critical to angiogenesis) were found to be modified by electrically stimulating NSCs, suggesting possible mechanisms for functional recovery.Disclosure: Dr. George has nothing to disclose. Dr. Bliss has nothing to disclose. Dr. Mehta has nothing to disclose. Dr. Hua has nothing to disclose. Dr. Sun has nothing to disclose. Dr. Steinberg has received personal compensation for activi...
Source: Neurology - April 8, 2015 Category: Neurology Authors: George, P., Bliss, T., Mehta, S., Hua, T., Sun, G., Steinberg, G. Tags: Cerebrovascular Disease and Interventional Neurology Poster Discussion Session Source Type: research
Predictors of Change in Quality of Life in Patients With Focal Neurological Damage Following an Outpatient Cognitive Rehabilitation Program (P1.284)
CONCLUSIONS:In patients with FND following an OCR program, the analysis of independent predictors of QoL change may allow for a better prediction of treatment response.Study Supported by:Disclosure: Dr. Rojas has nothing to disclose. Dr. Leis has nothing to disclose. Dr. Ciufia has nothing to disclose. Dr. Saux has nothing to disclose. Dr. Feldberg has nothing to disclose. Dr. Caceres has received personal compensation for activities with Abbott, Serono Inc., and Teva Neuroscience as a speaker. Dr. Demey has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Rojas, G., Leis, A., Ciufia, N., Saux, G., Feldberg, C., Caceres, F., Demey, I. Tags: Neural Repair and Neuro-rehabilitation: Basic Science Source Type: research
Neuroprotection Against Ischemic Brain Injury with Methylene Blue (P1.104)
Conclusion: This pre-clinical pilot study provides proof of principle that low-dose systemic MB given before lesion is effective at preventing ischemic brain injury. Additional studies should determine the effect of MB on long-term functional recovery, and determine if post-stroke administration of MB is effective in preventing ischemia-induced injury.Supported by: Haggerty Center for Research on Brain Injury and Repair in Stroke and P01 NS032636 (MPG)Disclosure: Dr. Rojas -Martinez has nothing to disclose. Dr. Plautz has nothing to disclose. Dr. Stowe has nothing to disclose. Dr. Goldberg has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Rojas, J., Plautz, E., Stowe, A., Goldberg, M. Tags: Cerebrovascular Disease and Interventional Neurology: Translational Science Source Type: research
Development of a Modified Central Nervous System Extracelluar Matrix with Polylysine. (P1.276)
Conclusion: Our data demonstrate proof of principle that modification of CNS-ECM with polylysine significantly improves neuron-ECM interaction. These preliminary data suggest that additional studies are warranted to further evaluate the affect of polylyine modified CNS-ECM on neurons.Disclosure: Dr. Marrotte has nothing to disclose. Dr. Zaher has nothing to disclose. Dr. Zhang has nothing to disclose. Dr. Chopp has received personal compensation for activities with EVER Pharmaceutical and Johnson & Johnson. Dr. Chopp has received license fee payments from RegenRx. Dr. Buller has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Marrotte, E., Zaher, N., Zhang, Y., Chopp, M., Buller, B. Tags: Neural Repair and Neuro-rehabilitation: Basic Science Source Type: research
