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Source: Neurology
Condition: Atrial Fibrillation

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Total 235 results found since Jan 2013.

Mobile Cardiac Outpatient Telemetry Identifies Occult Atrial Fibrillation After Cryptogenic Stroke (S12.004)
CONCLUSIONS:Atrial fibrillation is detected on MCOT in a substantial minority of cryptogenic stroke patients. Age蠅60 and the presence of prior cortical or cerebellar strokes should raise suspicion for occult AF. These data may aid in the selection of patients for prolonged arrhythmia monitoring.Disclosure: Dr. Ingala has nothing to disclose. Dr. Jara has nothing to disclose. Dr. Fessler has nothing to disclose. Dr. Cucchiara has received personal compensation for activities with Boehringer Ingelheim Pharmaceuticals, Inc. as a speaker. Dr. Messe has received personal compensation for activities with GlaxoSmithKline, ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ingala, E., Jara, J., Fessler, E., Cucchiara, B., Messe, S., Mullen, M., Prasad, A., Hutchinson, M., Kasner, S. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology and Risk Factors Source Type: research

Stroke Severity in Men and Women: What Proportion of the Disparity Can Be Explained by Differences in Cardiovascular Risk Factors? (S12.005)
Conclusion: In our biracial sample, women presented with more severe strokes than men. This difference remained significant even after adjustment for age, stroke subtype, and cardiovascular risk factors. Further, over 1/3 of the observed gender difference in stroke severity was unexplained.. Additional study is warranted to investigate the etiology of the gender differences in stroke severity.Disclosure: Dr. Albright has received research support from The Agency for Healthcare Research and Quality, and the National Institute on Minority Health and Health Disparities. Dr. Boehme has nothing to disclose. Dr. Sen has nothing ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Albright, K., Boehme, A., Sen, B., Mullen, M., Gonzales, N., Savitz, S., Martin-Schild, S. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology and Risk Factors Source Type: research

Infarction Volume in Patients With Atrial Fibrillation: The Impact of Left Ventricular Stiffness (S15.002)
CONCLUSIONS: We found that LV stiffness is independently related with large infarction volume in acute ischemic stroke related to Af. LV stiffness increases left atrial pressure and gives rise to flow stasis in left atrium which, in turn, may result in larger emboli in left atrium.Study Supported by:Disclosure: Dr. Hee Seung has nothing to disclose. Dr. Wi-Sun has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ahn, H.-S., Ryu, W.-S. Tags: Cerebrovascular Disease and Interventional Neurology: Clinical and Imaging Biomarkers and Genetics Source Type: research

The Collateral Circulation on Day-2 CT Angiography Is a Reliable Predictor of Functional Outcomes in Acute Ischemic Stroke. (S15.003)
Conclusion: Of the existing intracranial collaterals scoring systems, only the ASPECTS and Maas methods are reliable predictor of favourable outcomes.Disclosure: Dr. Yeo has nothing to disclose. Dr. Paliwal has nothing to disclose. Dr. Teoh has nothing to disclose. Dr. Chan has nothing to disclose. Dr. Seet has nothing to disclose. Dr. Ting has nothing to disclose. Dr. Lim has nothing to disclose. Dr. Ong has nothing to disclose. Dr. Shamugam has nothing to disclose. Dr. Varma has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Yeo, L., Paliwal, P., Teoh, H. L., Chan, B., Seet, C. S., Ting, E., Lim, G., Ong, V., Shamugam, G., Varma, A., Sharma, V. Tags: Cerebrovascular Disease and Interventional Neurology: Clinical and Imaging Biomarkers and Genetics Source Type: research

Areas of Cerebral Ischemia Have Increased Propensity to Convert to Infarct among Diabetics (P7.155)
CONCLUSIONS: PCT evaluation suggests that a lower CBV could explain worse outcomes among diabetics with stroke. Microvascular disease and endothelial dysfunction should be investigated as potential mechanisms for lower CBV and worse outcomes among diabeticsDisclosure: Dr. Mohamed has nothing to disclose. Dr. Reddy has nothing to disclose. Dr. Bhattacharya has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Mohamed, W., Reddy, S., Bhattacharya, P. Tags: Cerebrovascular Disease and Interventional Neurology: Predictors of Outcome After Ischemic Stroke Source Type: research

Effect of Apixaban on All-Cause Mortality in Atrial Fibrillation: An Imputed Placebo Analysis (I2-1.001)
CONCLUSIONS: This imputed placebo analysis suggests that apixaban significantly reduces all-cause mortality by about one-third in patients with AF.Study Supported by: Bristol-Myers Squibb Company and Pfizer Inc. Editorial assistance in formatting the abstract to ensure compliance with AAN guidelines was provided by Stephanie Finucane of Caudex Medical and was funded by Bristol-Myers Squibb Company and Pfizer Inc.Disclosure: Dr. McMurray has nothing to disclose. Dr. Hart has received personal compensation for activities with Sanofi-Aventis Pharmaceuticals Inc., and Bristol-Myers Squibb Co. Dr. Flaker has received personal c...
Source: Neurology - April 9, 2014 Category: Neurology Authors: McMurray, J., Hart, R., Flaker, G., Lopes, R., Wang, J., Hanna, M., Alexander, J., Granger, C., Wallentin, L. Tags: New Antithrombotic Agents for Stroke Prevention Poster Presentations Source Type: research

Diagnostic Yield of Prolonged Cardiac Rhythm Monitoring in Cryptogenic Stroke (I2-1.003)
CONCLUSIONS: Our study demonstrates the diagnostic yield of cardiac rhythm monitoring of up to 30 days is significantly lower than previously reported. This may be secondary to differences in monitoring devices used, the variability in definition of cryptogenic stroke, and duration of monitoring. Alternatively, longer duration of monitoring with implantable devices may be needed to detect paroxysmal AF, particularly in those with clinical, electrocardiographic or echocardiographic features associated with this dysrhythmia.Disclosure: Dr. Kalani has nothing to disclose. Dr. Bernstein has received personal compensation for a...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Kalani, R., Bernstein, R., Curran, Y., Ruff, I., Prabhakaran, S. Tags: New Antithrombotic Agents for Stroke Prevention Poster Presentations Source Type: research

Cryptogenic Stroke with No Cause Demonstrates the Outcome Prediction Utility of TOAST Classifications in a Large Stroke Patient Sample (I2-1.005)
Conclusion: Even after controlling for higher tPA treatment rates, patients with cryptogenic no cause by TOAST classification had better outcomes than other TOAST groups. Our results suggest that determining stroke etiology with the TOAST classification can be a clinical useful tool for risk stratification for stroke patients even with difficult diagnosis groups like cryptogenic no cause.Disclosure: Dr. Scullen has nothing to disclose. Dr. Monlezun, Jr has nothing to disclose. Dr. George has received research support from Tulane University School of Medicine. Dr. Siegler has nothing to disclose. Dr. Schwickrath has nothing...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Scullen, T., Monlezun, D., George, A., Siegler, J., Schwickrath, M., El Khoury, R., Martin-Schild, S. Tags: New Antithrombotic Agents for Stroke Prevention Poster Presentations Source Type: research

Neuroanatomical Correlates of Atrial Fibrillation: A Longitudinal MRI Study (I2-1.007)
Conclusions: The association of atrial fibrillation with volume loss in entorhinal cortex and middle temporal lobes may provide new insights into pathophysiology of atrial fibrillation.Disclosure: Dr. Saed has nothing to disclose. Dr. Tasneem has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Saed, A., Tasneem, N., Adil, M., Qureshi, M., Qureshi, A. Tags: New Antithrombotic Agents for Stroke Prevention Poster Presentations Source Type: research

Mobile Cardiac Outpatient Telemetry Identifies Occult Atrial Fibrillation After Cryptogenic Stroke (I2-2.002)
CONCLUSIONS:Atrial fibrillation is detected on MCOT in a substantial minority of cryptogenic stroke patients. Age蠅60 and the presence of prior cortical or cerebellar strokes should raise suspicion for occult AF. These data may aid in the selection of patients for prolonged arrhythmia monitoring.Disclosure: Dr. Ingala has nothing to disclose. Dr. Jara has nothing to disclose. Dr. Fessler has nothing to disclose. Dr. Cucchiara has received personal compensation for activities with Boehringer Ingelheim Pharmaceuticals, Inc. as a speaker. Dr. Messe has received personal compensation for activities with GlaxoSmithKline, ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ingala, E., Jara, J., Fessler, E., Cucchiara, B., Messe, S., Mullen, M., Prasad, A., Hutchinson, M., Kasner, S. Tags: New Antithrombotic Agents for Stroke Prevention Data Blitz Presentations Source Type: research

Use of Apixaban and Warfarin in Patients Undergoing Procedures: Insights from ARISTOTLE (I2-2.003)
CONCLUSIONS: Procedures are common in patients with atrial fibrillation. The majority of procedures are non-major and non-emergent, and anticoagulation therapy is likely to be stopped peri-procedure. Overall and among emergent procedures, rates of clinical events in the first 30 days post-procedure were low and comparable between treatment groups.Study Supported by: Bristol-Myers Squibb Company and Pfizer Inc. Editorial assistance (i.e., formatting the abstract to ensure compliance with AAN guidelines) was provided by Claire Hall of Caudex Medical and was funded by Bristol-Myers Squibb Company and Pfizer Inc.Disclosure: Dr...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Lopes, R., Garcia, D., Wojdyla, D., Dorian, P., Alexander, J., Wallentin, L., Lanas, F., Hanna, M., Held, C., Granger, C. Tags: New Antithrombotic Agents for Stroke Prevention Data Blitz Presentations Source Type: research

Infarction Volume in Patients With Atrial Fibrillation: The Impact of Left Ventricular Stiffness (I2-2.004)
CONCLUSIONS: We found that LV stiffness is independently related with large infarction volume in acute ischemic stroke related to Af. LV stiffness increases left atrial pressure and gives rise to flow stasis in left atrium which, in turn, may result in larger emboli in left atrium.Study Supported by:Disclosure: Dr. Hee Seung has nothing to disclose. Dr. Wi-Sun has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ahn, H.-S., Ryu, W.-S. Tags: New Antithrombotic Agents for Stroke Prevention Data Blitz Presentations Source Type: research

Poststroke atrial fibrillation: Cause or consequence?: Critical review of current views
Poststroke atrial fibrillation (AF) represents up to 1 of 4 overall AF cases in acute ischemic stroke. Current guidelines recommend oral anticoagulation for every ischemic stroke patient in whom AF is diagnosed. However, in some cases, AF detected after acute ischemic stroke may be short-lasting and perhaps a nonrecurrent autonomic and inflammatory epiphenomena of stroke. The autonomic regulation of cardiac rhythm constitutes an integrated relay system. The highest level of control is exerted by the cerebral cortex, particularly the insula. The onset of AF may be associated with an imbalance of sympathetic and parasympathe...
Source: Neurology - March 31, 2014 Category: Neurology Authors: Sposato, L. A., Riccio, P. M., Hachinski, V. Tags: Autonomic diseases, Cardiac, Embolism, Infarction VIEWS & amp;amp; REVIEWS Source Type: research

Long-term survival after ischemic stroke in patients with atrial fibrillation
Conclusions: Ischemic stroke approximately triples the mortality rate in patients with atrial fibrillation. This effect persists well beyond the immediate period poststroke and is strongly associated with disability after stroke. Stroke prevention by anticoagulation has even greater beneficial effects on survival than usually considered when focusing solely on 30-day mortality rates.
Source: Neurology - March 24, 2014 Category: Neurology Authors: Fang, M. C., Go, A. S., Chang, Y., Borowsky, L. H., Pomernacki, N. K., Udaltsova, N., Singer, D. E. Tags: Outcome research, Stroke prevention, Cardiac, Cohort studies, Infarction ARTICLE Source Type: research

Acute infection contributes to racial disparities in stroke mortality
Conclusions: Acute infection disproportionately increases the risk of stroke death for non-Hispanic blacks, independently of atrial fibrillation. Stroke incidence did not explain this finding. Acute infection appears to be one factor that contributes to the black–white disparity in stroke mortality.
Source: Neurology - March 17, 2014 Category: Neurology Authors: Levine, D. A., Langa, K. M., Rogers, M. A. M. Tags: Outcome research, All Infections, All Cerebrovascular disease/Stroke ARTICLE Source Type: research