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Case Report - IV Thrombolysis with Subsequent SAH in Setting of Occult Spontaneous MCA Dissection (P4.346)
Conclusions: Spontaneous isolated middle cerebral artery dissection is a rare entity which most commonly presents as ischemic stroke and may complicate the administration of IV-rtPA. It should be considered in cases of thrombolysis and development of subsequent SAH.Disclosure: Dr. Saeed has nothing to disclose. Dr. Chaudhry has nothing to disclose. Dr. Bunka has nothing to disclose. Dr. Razak has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Saeed, A., Chaudhry, S., Bunka, J., Razak, A. Tags: Cerebrovascular Case Reports Source Type: research

Risk of Pregnancy-Associated Stroke Across Age Groups: Population-Based Data from New York State (I5.005)
Conclusions: Younger peripartum women, but not older women, are at increased risk of stroke compared to non-pregnant contemporaries. These results suggest that pregnancy itself does not increase the risk of stroke in older women, though they could reflect a tendency for older pregnant women to have above-average cardiovascular health. More research is needed to investigate why younger women may have increased risk of PAS.Disclosure: Dr. Miller has nothing to disclose. Dr. Gatollari has nothing to disclose. Dr. Too has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Colello has nothing to disclose. Dr. Leffert ...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Miller, E., Gatollari, H., Too, G., Boehme, A., Colello, A., Leffert, L., Elkind, M., Willey, J. Tags: Sex-related Factors in Neurological Disease Data Blitz Presentations Source Type: research

COLADAS: Caribbean Origin Latin Americans Disparities in Acute Stroke (I5.006)
Conclusions: Our study reveals intrinsic sex differences that may imply under treatment. Understanding the reasons underlying these "sex-gaps" is critical. Study Supported By: Award Number Grants 5S21MD000242 and 5S21MD000138, from the National Center for Minority Health and Health Disparities, National Institutes of Health (NCMHD-NIH).Disclosure: Dr. Teron Molina has nothing to disclose. Dr. Rodríguez Centeno has nothing to disclose. Dr. Santiago has nothing to disclose. Dr. López Valentín has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Teron Molina, I., Rodriguez Centeno, A., Santiago, F., Lopez Valentin, M. Tags: Sex-related Factors in Neurological Disease Data Blitz Presentations Source Type: research

Utility of Brain MRI in Infective Endocarditis (S46.004)
CONCLUSIONS: In hospitalized patients with IE, ICH was associated with unfavorable clinical outcomes. However, in patients undergoing valve surgery, microbleeds on MRI were not associated with development of postoperative ICH. Preoperative brain MRI may result in a delay to surgery and did not have an impact on outcome. Thus, the clinical utility of brain MRI in patients with IE remains uncertain.Disclosure: Dr. Chakraborty has nothing to disclose. Dr. Scharf has nothing to disclose. Dr. DeSimone has nothing to disclose. Dr. Abdelghani has nothing to disclose. Dr. Rabinstein has received royalty payments from Elsevier and ...
Source: Neurology - February 7, 2016 Category: Neurology Authors: Chakraborty, T., Scharf, E., DeSimone, D., Abdelghani, E.-R., Rabinstein, A., Wijdicks, E., Baddour, L., Fugate, J. Tags: Critical Care Source Type: research

Observations of Paradoxical ICP Patterns within 24 Hours Preceding Neurovascular Related Mortality (S46.005)
CONCLUSIONS: In this series patients with quick neurovascular mortality after EVD placement were found to have paradoxical ICP pulse patterns, contradicting the classic teachings of increased ICP waveforms. These patterns may indicate different etiologies of elevated ICP. These observations need to be studied prospectively to ascertain clinical utility in the management of neurovascular patients.Disclosure: Dr. Sampognaro has nothing to disclose. Dr. Shah has nothing to disclose. Dr. Smith has received personal compensation for activities with Stryker Neurovascular and Covidien as a consultant. Dr. Hu has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Sampognaro, P., Shah, N., Smith, W., Hu, X. Tags: Critical Care Source Type: research

Teaching NeuroImages: Hyperintense acute reperfusion marker in ischemic stroke with transient symptoms
A 67-year-old man with 45-minute onset left hemiparesis underwent 3.0T gadolinium-enhanced MRI (reported iodine contrast allergy) with right frontoparietal small infarcts on diffusion-weighted images without vascular obstruction. No reperfusion therapy was given due to complete spontaneous symptoms regression. Twenty-four hours later, a second MRI showed right parietal CSF space enhancement on fluid-attenuated inversion recovery. Neither MRI nor CT had sign of hemorrhage (figure).
Source: Neurology - January 11, 2016 Category: Neurology Authors: Patroclo, C. B., Picanco, M. R., Bandeira, A. C. N., Carvalho, V. S. d., Bezerra, D. d. C. Tags: All Imaging, MRI, Embolism, Infarction, Subarachnoid hemorrhage RESIDENT & amp;amp; FELLOW SECTION Source Type: research

Small DWI lesions after intracerebral hemorrhage: Are perivascular spaces the missing link?
The MRI era has provided vascular neurologists with a number of novel imaging markers that associate with clinical outcomes in stroke and cerebrovascular disease. Examples include periventricular white mater hyperintensities, lobar and deep cerebral microbleeds, cortical superficial siderosis, and cerebral microinfarcts.1,2 Recently, MRI-visible perivascular spaces (or Virchow-Robin spaces) have been associated with both deep and lobar intracerebral hemorrhage (ICH),3 and have therefore garnered increasing attention. Although classically thought of as extensions of the subarachnoid space coursing with penetrating cerebral ...
Source: Neurology - December 7, 2015 Category: Neurology Authors: Anderson, C. D., Charidimou, A. Tags: MRI, DWI, Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Extensive stretching of intracranial aneurysm coil causing TIAs
A 58-year-old man with a history of ruptured posterior cerebral artery aneurysm, repaired with coil embolization 5 years previously, presented with right hemi-numbness lasting 30 minutes. Cerebral MRI did not reveal acute stroke. CT angiogram showed a stretched wire complex extending through the posterior communicating artery, down the carotid artery, and into the most inferior visualized portion of descending aorta, terminating in a loosely coiled wire (figure, A and B). A transesophageal echocardiogram showed evidence of a possible thrombus on the coil in the aortic arch (figure, C and D; video on the Neurology® Web ...
Source: Neurology - November 2, 2015 Category: Neurology Authors: Itrat, A., Toth, G., Min, D., Hussain, M. S. Tags: Stroke prevention, Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, Embolism, Subarachnoid hemorrhage VIDEO NEUROIMAGES Source Type: research

Hemorrhagic stroke following use of the synthetic marijuana "spice"
The association between the street drug spice (K-2 or herbal incense), a synthetic marijuana, and intracranial hemorrhage (ICH) has not yet been described, but it has with acute ischemic stroke (AIS),1 seizure, and myocardial infarction.2 Two young patients (31 and 25 years old) independently presented to our hospital with subarachnoid hemorrhage (SAH) after spice inhalation. The first also had 2 large intraparenchymal hemorrhages (IPH); the other also had AIS. Both were previously healthy without hypertension, coagulopathy, bleeding diathesis, thrombocytopenia, intracranial aneurysm, arteriovenous malformation, connective...
Source: Neurology - September 28, 2015 Category: Neurology Authors: Rose, D. Z., Guerrero, W. R., Mokin, M. V., Gooch, C. L., Bozeman, A. C., Pearson, J. M., Burgin, W. S. Tags: Stroke in young adults, Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, Other toxicology, Intracerebral hemorrhage CLINICAL/SCIENTIFIC NOTES Source Type: research

CT within 6 hours of headache onset to rule out subarachnoid hemorrhage in nonacademic hospitals
Conclusions: Our results support a change of practice wherein a lumbar puncture can be withheld in patients with a head CT scan performed <6 hours after headache onset and reported negative for the presence of SAH by a staff radiologist in the described nonacademic setting.
Source: Neurology - May 11, 2015 Category: Neurology Authors: Blok, K. M., Rinkel, G. J. E., Majoie, C. B. L. M., Hendrikse, J., Braaksma, M., Tijssen, C. C., Wong, Y. Y., Hofmeijer, J., Extercatte, J., Kerklaan, B., Schreuder, T. H. C. M. L., ten Holter, S., Verheul, F., Harlaar, L., Pruissen, D. M. O., Kwa, V. I. Tags: All Headache, Diagnostic test assessment, CT, Subarachnoid hemorrhage ARTICLE Source Type: research

Stroke In Young Adults: A 4-Year Retrospective Hospital-Based Study, First Report From United Arab Emirates (P1.020)
CONCLUSIONS: Stroke in young adults is prevalent in our region; main cause is unknown. The increased mortality in this age population is alarming requiring better risk-factor control measures. MR: Mortality rates, ICH: intracerebral hemorrhage, SAH: subarachnoid hemorrhageDisclosure: Dr. AlAmeri has nothing to disclose. Dr. AlNuaimi has nothing to disclose. Dr. Alsaadi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: AlAmeri, M., AlNuaimi, A., Alsaadi, T. Tags: Cerebrovascular Disease and Interventional Neurology I ePosters Source Type: research

Troponin Elevation in Spontaneous Intracranial Hemorrhage (P3.088)
CONCLUSIONS: Troponin elevation in sICH does not appear to be associated with hematoma characteristics. However, it is significantly associated with mortality status of the patients at discharge. GCS on admission and systolic blood pressure were predictors for in-hospital mortality. Whether troponin elevation independently contributes to mortality in sICH requires further investigation.Disclosure: Dr. Tummala has nothing to disclose. Dr. Makhlouf has nothing to disclose. Dr. Kumar has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Tummala, P., Makhlouf, N., Kumar, A. Tags: Cerebrovascular Disease and Interventional Neurology: Intracerebral Hemorrhage Source Type: research

Stroke Patterns and Short Term Mortality in Marijuana Users and Non-Users: A Cross-Sectional Study (P1.061)
CONCLUSIONS: Our findings suggest that the SAH patients have higher rate of positive THC test in urine than other stroke types. Marijuana use has no effect on post-stroke in-hospital mortality. Study Supported by: NoneDisclosure: Dr. Mittal has nothing to disclose. Dr. Adabala has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Mittal, M., Adabala, N. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

Recreational drug use and RCVS: should toxicity screens become standard in RCVS diagnostics? (P2.284)
CONCLUSIONS: As we transition into a new culture of researching marijuana derivatives to treat a multitude of neurologic diseases including pain syndromes, epilepsy, and multiple sclerosis we must also consider the vasoactive properties of the substance and potential vascular complications. This also raises the importance of improving drug screening in such patients with high suspicion of RCVS on admission and identifying high risk patients to prevent further vascular complications. Study Supported by:Disclosure: Dr. Mirchandani has nothing to disclose. Dr. Khan has nothing to disclose. Dr. Wajnsztajn has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Mirchandani, N., Khan, I., Wajnsztajn, F. Tags: Cerebrovascular Disease and Interventional Neurology: RCVS and Malignant Cerebral Edema Source Type: research

Port Harcourt Stroke Registry: A Prospective Hospital Based Study. (P1.074)
CONCLUSION: This Stroke Registry, first of its kind from this region of Nigeria presents a handy tool to track the epidemiology of stroke in this region. It will contribute to stroke prevention by providing the evidence required to formulate policies and measures required to control identified risk factors.Disclosure: Dr. Okunoye has nothing to disclose. Dr. Asekomeh has nothing to disclose. Dr. Iyagba has nothing to disclose. Dr. Onwuchekwa has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Okunoye, C., Asekomeh, G., Iyagba, A., Onwuchekwa, A. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

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