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Condition: Diabetes

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Total 299 results found since Jan 2013.

Meeting the challenges of stroke in india
Worldwide, cerebrovascular diseases are responsible for 6.15 million deaths (10.8% of all deaths)1 and are the second most common cause of mortality; 87% of stroke deaths occur in low or middle income countries.2 With the world's second largest population, India is witnessing several adverse trends for the cardiovascular health of its population, including a rapid rise in the proportion of patients with diabetes and dyslipidemia, and the relative lack of exercise among the general population. India has the world's largest population of patients with diabetes, with over 62 million people with diabetes in 2011.3 At the curre...
Source: Neurology - June 10, 2013 Category: Neurology Authors: Mehndiratta, M. M., Singhal, A. B., Chaturvedi, S., Sivakumar, M. R., Moonis, M. Tags: All Cerebrovascular disease/Stroke GLOBAL PERSPECTIVES Source Type: research

Mild cognitive impairment: Incidence and vascular risk factors in a population-based cohort
Conclusion: Incidence of MCI increased with age regardless of definition and did not vary by sex or education. Several vascular risk factors elevated the risk of incident MCI, whether defined cognitively or functionally, but most were associated with nonamnestic MCI and CDR = 0.5. Controlling vascular risk may potentially reduce risk of MCI.
Source: Neurology - June 3, 2013 Category: Neurology Authors: Ganguli, M., Fu, B., Snitz, B. E., Hughes, T. F., Chang, C.-C. H. Tags: MCI (mild cognitive impairment), Cohort studies, Incidence studies, Risk factors in epidemiology ARTICLE Source Type: research

Adherence to a Mediterranean diet and risk of incident cognitive impairment
Conclusions: Higher adherence to MeD was associated with a lower likelihood of ICI independent of potential confounders. This association was moderated by presence of diabetes mellitus.
Source: Neurology - April 29, 2013 Category: Neurology Authors: Tsivgoulis, G., Judd, S., Letter, A. J., Alexandrov, A. V., Howard, G., Nahab, F., Unverzagt, F. W., Moy, C., Howard, V. J., Kissela, B., Wadley, V. G. Tags: All Cognitive Disorders/Dementia, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Teaching NeuroImages: Comatose patient with bilateral thalamic infarct due to internal carotid artery occlusion
An 88-year-old woman with a medical history of diabetes, hypertension, and atrial fibrillation presented to the emergency room after being found unresponsive with a NIH Stroke Scale score of 23 and Glasgow Coma Scale score of 3. She was unresponsive to painful stimuli. Noncontrast CT demonstrated bilateral thalamic infarcts (figure 1A).
Source: Neurology - April 22, 2013 Category: Neurology Authors: Dababneh, H., Shikhman, A., Moussavi, M., Guerrero, W. R., Panezai, S., Kirmani, J. F. Tags: CT, MRI, Coma, All Cerebrovascular disease/Stroke, Infarction RESIDENT AND FELLOW SECTION Source Type: research

Premature atherosclerosis: A major contributor to early-onset ischemic stroke
Atherosclerosis is an age-dependent process. The prevalence of large-artery atherosclerosis in case series of ischemic stroke in young adults has been substantially less than in older adults.1–4 Historically, data on the role of atherosclerosis in early-onset stroke have been limited for a variety of reasons. First, multi-institutional studies often have inconsistent evaluations of the cerebral vasculature, particularly the intracranial circulation. Second, studies may not report evidence for proximal atherosclerosis less severe than necessary to meet criteria for etiology. Emerging data, however, show a high inciden...
Source: Neurology - April 1, 2013 Category: Neurology Authors: Kittner, S. J., Singhal, A. B. Tags: Stroke in young adults, Ultrasound, Prevalence studies, Risk factors in epidemiology EDITORIALS Source Type: research

Disparities among Asians and Native Hawaiians and Pacific Islanders with ischemic stroke
Conclusions: Asians, NHPI, and whites with ischemic stroke have substantially different cardiovascular risk factors. Targeted secondary prevention will be important in reducing disparities among these racial groups.
Source: Neurology - February 25, 2013 Category: Neurology Authors: Nakagawa, K., Koenig, M. A., Asai, S. M., Chang, C. W., Seto, T. B. Tags: All Cerebrovascular disease/Stroke, Risk factors in epidemiology ARTICLE Source Type: research

Use of ACEI in Migraine Prophylaxis: Why We Don't Look Back? (P01.092)
CONCLUSIONS: ACEI have a lower profile of side effects compared to other blood pressure medications currently used in migraine prophylaxis. The benefits with ACEI recognized in the management of congestive heart failure, hypertension associated with diabetes and secondary stroke prevention maybe can be extrapolated to a younger population. Early initiation of an ACEI in patients with migraine attacks can possibly reduce the incidence of stroke in a population at a higher risk of it later in life.Disclosure: Dr. Delgado has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Delgado, A. Tags: P01 Headache: Clinical Presentation and Therapeutics Source Type: research

Effect of HbA1c Level on Discharge Modified Rankin Scale Who Received rt-PA in Acute Ischemic Stroke (P01.224)
CONCLUSIONS: Clinical outcomes quantified by discharge mRS in patients with ischemic strokes treated with rt-PA is indeed dependent on HbA1c levels. Patients suffering from ischemic strokes with well controlled diabetes will ultimately have better clinical outcomes. Disclosure: Dr. Hussain has nothing to disclose. Dr. Dababneh has nothing to disclose. Dr. Mehta has nothing to disclose. Dr. Dass has nothing to disclose. Dr. Ahmad has nothing to disclose. Dr. Moussavi has nothing to disclose. Dr. Panezai has nothing to disclose. Dr. Kirmani has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Hussain, M., Dababneh, H., Mehta, S., Dass, P., Ahmad, J., Moussavi, M., Panezai, S., Kirmani, J. Tags: P01 Cerebrovascular Disease I Source Type: research

Can Patient or Arterial Characteristics Guide the Choice between Carotid Angioplasty and Carotid Endarterectomy? The Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) (P01.225)
CONCLUSIONS: Beyond the previously described differential treatment efficacy by age, there were no other patient or arterial characteristic detected to identify patient subgroups that would differentially benefit from the choice of CAS versus CEA. Our inability to identify factors to guide treatment choices could be due to the low number of stroke and death events, incomplete information regarding arterial characteristics in the CEA population, or the potential exclusion of "high risk" groups (such as those with severe arterial tortuosity) from the study.Disclosure: Dr. Moore has nothing to disclose. Dr. Roubin has receive...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Moore, W., Roubin, G., Rosenfield, K., Altafullah, I., Ansel, G., Voeks, J., Meschia, J., Lal, B., Howard, G., Brott, T. Tags: P01 Cerebrovascular Disease I Source Type: research

Transthoracic Echocardiography for Lacunar Strokes: Do We Need It in All Patients? (P01.234)
CONCLUSIONS: Left ventricular hypertrophy is considered sine qua non of hypertensive control, which is one of the major risk factors for lacunar stroke. In our series we did not find any intracardiac abnormality except for LVH which was almost exclusively in patients with hypertension. TTE adds to the stroke workup cost and should be used only in selected cases.Disclosure: Dr. Suchdev has nothing to disclose. Dr. Damani has nothing to disclose. Dr. Varade has nothing to disclose. Dr. Abhishek has nothing to disclose. Dr. Norris has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Suchdev, K., Damani, R., Varade, P., Abhishek, F., Norris, G. Tags: P01 Cerebrovascular Disease I Source Type: research

Early Spontaneous Recanalization of Symptomatic Carotid Occlusion: When Should We Be Looking? (P01.238)
CONCLUSIONS: Spontaneous recanalization of an occluded carotid artery may occur in a subacute fashion. Clinical deterioration, even minor, should prompt an investigation into possible recanalization.Disclosure: Dr. Cutting has received personal compensation for activities with F1000. Dr. Conners has nothing to disclose. Dr. Prabhakaran has nothing to disclose. Dr. Song has received personal compensation in an editorial capacity for serving as Advocacy Editor for AAN.com.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Cutting, S., Conners, J., Prabhakaran, S., Song, S. Tags: P01 Cerebrovascular Disease I Source Type: research

Predictors of Good Clinical Outcome in Acute Stroke Patients Underwent Recanalization Therapy (P01.242)
CONCLUSIONS: NIHSS at admission, recanalization grade and early neurological improvement are independent predictors of clinical outcome in AIS patients underwent mechanical recanalization.Supported by: IGA MH CR grants NT/11386-5/2010, NT/11046-6/2010, NT/13498-4/2012.Disclosure: Dr. Skoloudik has nothing to disclose. Dr. Roubec has nothing to disclose. Dr. Kuliha has nothing to disclose. Dr. Herzig has received personal compensation for activities with Bayer, Boehringer Ingelheim Pharmaceuticals, Inc., and Gedeon Richter. Dr. Sanak has received personal compensation from Boehringer Ingelheim for serving on a scientific ad...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Skoloudik, D., Roubec, M., Kuliha, M., Herzig, R., Sanak, D., Prochazka, V., Hrbac, T. Tags: P01 Cerebrovascular Disease I Source Type: research

Discharge Outcomes of Ischemic Stroke Patients with Diabetes: Get with the Guidelines (P01.250)
CONCLUSIONS: Our data suggest DM may impact ambulatory status at discharge. While limited by less objective evaluations of stroke severity, the impact of DM on discharge disposition of IS patients warrants further study.Disclosure: Dr. Salem has nothing to disclose. Dr. Pikula has nothing to disclose. Dr. Lau has nothing to disclose. Dr. Nguyen has nothing to disclose. Dr. Shoamanesh has nothing to disclose. Dr. Kase has nothing to disclose. Dr. Babikian has nothing to disclose. Dr. Romero has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Salem, R., Pikula, A., Lau, H., Nguyen, T., Shoamanesh, A., Kase, C., Babikian, V., Romero, J. Tags: P01 Cerebrovascular Disease I Source Type: research

Incidence and Types of Seizures in Acute - A Single Center Experience (P01.252)
CONCLUSIONS: This is one of the largest studies describing occurrence of seizures post stroke. Seizures occurred in 7.9 % of patients with stroke. Focal seizures were the most common type and MCA territory infarcts were more likely to be associated with seizures. PSS were more likely to occur in those with ischemic infarcts as compared to hemorrhagic infarcts.Disclosure: Dr. Mehndiratta has nothing to disclose. Dr. Mehndiratta has nothing to disclose. Dr. Kumar has nothing to disclose. Dr. Nayak has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Mehndiratta, M. M., Mehndiratta, P., Kumar, M., Nayak, R. Tags: P01 Cerebrovascular Disease I Source Type: research

Management of Early Severe Hypertension in Acute Intracerebral Hemorrhage in Primary Stroke Centers vs. Non-Stroke Center Hospitals (P01.022)
CONCLUSIONS: Antihypertensives were initiated earlier for ICH at PSCs, however steroid utilization was no different. This suggests that routing stroke patients to PSCs may improve timeliness of antihypertensive therapy for ICH and greater education requiring avoidance of steroids is desirable even within PSCs.Disclosure: Dr. Flinders has nothing to disclose. Dr. Sanossian has received personal compensation for activities with Boehringer-Ingelheim as speaker. Dr. Starkman has received research support from the National Institutes of Health, Lundbeck, Mitsubishi, and NTI. Dr. Liebeskind has received personal compensation for...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Flinders, A., Sanossian, N., Starkman, S., Liebeskind, D., Eckstein, M., Stratton, S., Pratt, F., Hamilton, S., Olivas, E., Chatfield, F., Conwit, R., Saver, J. Tags: P01 Neurocritical Care: Clinical Neurophysiology/Therapeutics Source Type: research