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Source: Neurology
Condition: Headache

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Total 267 results found since Jan 2013.

Are Triptans safe in Basilar and Hemiplegic Migraine? A retrospective chart review (S23.002)
CONCLUSIONS: Our retrospective study showed that Triptans are safe medication for use in both basilar and hemiplegic migraine and are not associated with stroke. Study Supported by: NoneDisclosure: Dr. Singh has nothing to disclose. Dr. Sherman has nothing to disclose. Dr. Zinkhan has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Singh, G., Sherman, J., Zinkhan, G. Tags: Headache: Epidemiology and Clinical Source Type: research

TIA Biomarkers Determined Through Proteomics (S30.002)
Conclusions: PBP has been identified as potential serum biomarker for TIA. Larger sample size may find that ceruloplasmin is an additional candidate. Ultimately, a panel of proteins may be required. Larger studies are needed to determine the validity of these proteins in clinical use.Disclosure: Dr. George has nothing to disclose. Dr. Mlynash has nothing to disclose. Dr. Adams has nothing to disclose. Dr. Kuo has nothing to disclose. Dr. Kemp has nothing to disclose. Dr. Garcia has nothing to disclose. Dr. Albers has received personal compensation for activities with Genentech, Inc. and Lundbeck Research USA, Inc. as an ad...
Source: Neurology - April 8, 2015 Category: Neurology Authors: George, P., Mlynash, M., Adams, C., Kuo, C., Kemp, S., Garcia, M., Albers, G., Olivot, J.-M. Tags: Cerebrovascular Disease and Interventional Neurology: Diagnostics, Biomarkers, and Genetics Platform Blitz Source Type: research

Internet Teaching of the Neurologic Examination and OSCE Performance in the Neurology Clerkship (s19.006)
CONCLUSIONS Using www.neuroexam.com significantly improved students’ performance on a Stroke OSCE compared to online NIHSS training, with similar trends for Headache and Neuropathy. General neurologic examination training rather than focused stroke examination training may be more helpful for students, even when examining stroke patients. Online websites with teaching videos may represent a viable model for improving students’ skills with the neurologic examination. Study supported by: 2013 AAN Education Research GrantDisclosure: Dr. Harth has nothing to disclose. Dr. Xue has nothing to disclose. Dr. Yang has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Harth, C., Xue, Y., Yang, J. Tags: Neurologic Education Source Type: research

Vertebral artery hypoplasia and vertebral artery dissection: A hospital-based cohort study
Conclusions: sVAD is associated with ipsilateral VAH and occurs more frequently in hypoplastic VAs than in their normal counterparts.
Source: Neurology - February 23, 2015 Category: Neurology Authors: Zhou, M., Zheng, H., Gong, S., Guo, J., Chen, N., Zhou, D., Yang, R., Zhu, C., He, L. Tags: Other cerebrovascular disease/ Stroke, Clinical trials Observational study (Cohort, Case control) ARTICLE Source Type: research

Clinical Reasoning: An unusual case of subacute encephalopathy
A 52-year-old previously healthy man presented with 8 months of progressive cognitive decline. He complained of months of confusion, fatigue, depression, hypersomnolence, headaches, and, subsequently, urinary incontinence and unsteady gait. His family reported that he spoke of his deceased mother as if she were alive. His executive deficits progressed, leading to termination of his employment and a motor vehicle accident. He was evaluated and treated in Morocco before presenting to our institution for further care.
Source: Neurology - February 9, 2015 Category: Neurology Authors: Parikh, N., Merkler, A. E., Cheng, N. T., Baradaran, H., White, H., Leifer, D. Tags: All Cerebrovascular disease/Stroke, Arteriovenous malformation, Cerebral venous thrombosis RESIDENT AND FELLOW SECTION Source Type: research

Teaching NeuroImages: Cortical blindness following acute obstructive hydrocephalus by a colloid cyst
A 46-year-old woman was admitted for acute headache, postseizure confusion, and visual loss. Urgent head CT scan showed obstructive hydrocephalus due to a colloid cyst (figure 1). External ventricular drains inserted emergently demonstrated CSF under pressure, above 40 mm H2O. MRI confirmed the suspected diagnosis of a colloid cyst and highlighted bilateral occipital lobe infarcts (figure 2). CT angiography showed no thrombosis of the posterior cerebral arteries (PCAs). After neurosurgical excision of the colloid cyst, the patient remained blind. The presumed mechanism of infarction was acute compression of the PCAs agains...
Source: Neurology - February 9, 2015 Category: Neurology Authors: Champeaux, C., Grivas, A. Tags: Hydrocephalus, Stroke in young adults, MRI, Clinical neurology examination, Visual loss RESIDENT AND FELLOW SECTION Source Type: research

Reduced trigeminovascular cyclicity in patients with menstrually related migraine
Conclusions: Our study provides evidence for a reduced menstrual cyclicity of both estradiol levels and the trigeminovascular vasodilator system in patients with MRM.
Source: Neurology - January 12, 2015 Category: Neurology Authors: Ibrahimi, K., van Oosterhout, W. P. J., van Dorp, W., Danser, A. H. J., Garrelds, I. M., Kushner, S. A., Lesaffre, E. M. E. H., Terwindt, G. M., Ferrari, M. D., van den Meiracker, A. H., MaassenVanDenBrink, A. Tags: Migraine, Other cerebrovascular disease/ Stroke, All Clinical Neurology ARTICLE Source Type: research

Teaching NeuroImages: Magnetic resonance susceptibility effect for acute isolated cortical vein thrombosis
A 38-year-old woman using hormonal contraception presented with right-sided abdominal and arm clonic seizures, right hemiparesis, hypesthesia, and nausea. She denied headache. D-dimers were 350 ng/mL (laboratory reference ≤500 ng/mL). CT showed a small left parietal hemorrhagic infarct with adjacent hyperdense cortical vein (figure 1). MRI 15 hours after onset showed magnetic susceptibility effect on susceptibility-weighted imaging (SWI, figure 2). Isolated cortical vein thrombosis is present in 5% of patients with cerebral venous thrombosis (CVT).1 Negative D-dimer and absence of headache does not exclude CVT1 and SWI ...
Source: Neurology - November 10, 2014 Category: Neurology Authors: Pikija, S., Unterkreuter, P., Knoflach, M. Tags: Stroke in young adults, All Cerebrovascular disease/Stroke, All Epilepsy/Seizures RESIDENT AND FELLOW SECTION Source Type: research

Cerebrovascular regulation, exercise, and mild traumatic brain injury
A substantial number of people who sustain a mild traumatic brain injury report persistent symptoms. Most common among these symptoms are headache, dizziness, and cognitive difficulties. One possible contributor to sustained symptoms may be compromised cerebrovascular regulation. In addition to injury-related cerebrovascular dysfunction, it is possible that prolonged rest after mild traumatic brain injury leads to deconditioning that may induce physiologic changes in cerebral blood flow control that contributes to persistent symptoms in some people. There is some evidence that exercise training may reduce symptoms perhaps ...
Source: Neurology - October 27, 2014 Category: Neurology Authors: Tan, C. O., Meehan, W. P., Iverson, G. L., Taylor, J. A. Tags: Other cerebrovascular disease/ Stroke, All Rehabilitation, Other toxicology VIEWS & amp;amp; REVIEWS Source Type: research

Biopsy-negative PET-positive giant-cell arteritis
We present a case of biopsy-negative GCA in which PET-CT revealed evidence of extensive large-vessel vasculitis.
Source: Neurology - October 27, 2014 Category: Neurology Authors: Al-Louzi, O., Hauptman, H., Saidha, S. Tags: All Headache, Secondary headache disorders, CT, PET CLINICAL/SCIENTIFIC NOTES Source Type: research

Mystery Case: Cerebral amyloid angiopathy-related inflammation
A 59-year-old man was arrested for unruly public behavior. He was subsequently found unresponsive with bilateral upper extremity extensor posturing and lower extremity triple flexion when stimulated. Over the next 48 hours, he awoke and became belligerent. MRI revealed innumerable cortical microhemorrhages on susceptibility-weighted imaging (figure, A) and asymmetric subcortical T2 hyperintensities (figure, B) consistent with cerebral amyloid angiopathy–related inflammation (CAA-ri).1 With corticosteroid treatment, he rapidly became calm and conversant, returning to near his premorbid baseline with only mild residual...
Source: Neurology - October 27, 2014 Category: Neurology Authors: Berkowitz, A. L., Baker, J. M., Miller, J. J., Greenberg, S. M. Tags: MRI, All Immunology, All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

Heterogeneity in neurologic education and care in Asian and Oceanian region
The Asian subcontinent and Oceania (comprising islands in the Pacific Ocean) are home to more than 60% of the world's population. The burden of neurologic disease and sickness is thereby high and medical care is in high demand. There are many developing countries with diverse cultural, economical, political, religious, and historical backgrounds within the Asian and Oceanian region.1,2 Recently, enhanced medical care in these developing countries has resulted in greater longevity, which has increased the burden on those providing health care. The prevalence of neurologic illness has also increased and has emerged as a prio...
Source: Neurology - August 25, 2014 Category: Neurology Authors: Mehndiratta, M. M., Mehndiratta, P., Gulati, N. S., Wasay, M. Tags: All Clinical Neurology, All Education, CME GLOBAL PERSPECTIVES Source Type: research

Clinical Reasoning: A 42-year-old man who developed blurred vision and dropped his iPod while jogging
A 42-year-old man noted sudden onset of blurriness in his left eye and dropped his iPod from his right hand while jogging. In the emergency room, it was noted that visual blurring resolved with right eye closure, but his ophthalmologic examination was otherwise normal. He had subtle right nasolabial fold flattening and right arm pronator drift. His examination was otherwise normal. He reported no headache, neck pain, prior trauma, prior transient neurologic deficit, or palpitations. He took no medications and did not smoke, drink alcohol, or use illicit drugs.
Source: Neurology - August 18, 2014 Category: Neurology Authors: Berkowitz, A. L., Voinescu, P. E., Feske, S. K. Tags: All Cerebrovascular disease/Stroke, Carotid artery dissection RESIDENT AND FELLOW SECTION Source Type: research

Neurology in Africa
"Ex Africa semper aliquid novi [Out of Africa always something new]," wrote the Roman historian Pliny the elder. Neurology in Africa is no different, with the recent emergence of new diseases ranging from HIV to konzo. Historically, neurology in Africa has been included under the heading tropical neurology or neurology in the tropics and is well-reviewed by Poser and Poser.1 Some of the earliest descriptions of the more common neurologic disorders (ND), including stroke, migraine, paralysis, and seizures, come from ancient Egypt and Greece. These accounts include diseases like lathyrism, which occurs in temperate as well a...
Source: Neurology - August 11, 2014 Category: Neurology Authors: Howlett, W. P. Tags: GLOBAL PERSPECTIVES Source Type: research

Reversible cerebral vasoconstriction syndrome following carotid stenting
A 60-year-old woman on venlafaxine presented with headache and left-sided weakness 1 month after undergoing right common carotid artery stenting. Catheter-based angiogram identified new irregularities of the right anterior cerebral and right middle cerebral artery (figure, A–C). Investigations for vasculitis, including CSF studies, were unremarkable. The vessel irregularities and symptoms improved after administration of intra-arterial verapamil (figure, D–F). Unilateral reversible cerebral vasoconstriction syndrome has previously been described after carotid endarterectomy. The mechanism is unclear; however, i...
Source: Neurology - August 4, 2014 Category: Neurology Authors: Aghaebrahim, A., Jadhav, A. P., Saeed, Y., Totoraitis, R., Jankowitz, B. T., Jovin, T. G., Molyneaux, B. J. Tags: All Cerebrovascular disease/Stroke, Infarction NEUROIMAGES Source Type: research