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Source: Neurology
Condition: Headache
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Total 267 results found since Jan 2013.
OnabotulinumtoxinA in Lower Limb Spasticity: Safety Results from a Pooled Analysis (P03.266)
CONCLUSIONS: OnabotulinumtoxinA treatment in lower limb spasticity was found to be safe and well-tolerated. Majority of AEs were considered not related to onabotulinumtoxinA and treatment-related AEs are consistent with the known mechanism of action of onabotulinumtoxinA.Supported by: Allergan, Inc.Disclosure: Dr. Earl has received personal compensation for activities with Allergan, Inc. as an employee. Dr. Earl holds stock and/or stock options in AGN and GlaxoSmithKline, Inc. Dr. James has received personal compensation for activities with Allergan, Inc as an employee. Dr. Li has received personal compensation for activit...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Earl, N., James, L., Li, H.-I., Shi, G., Demos, G., Dimitrova, R. Tags: P03 Neural Repair Source Type: research
A Novel Mutation in the Mitochondrial DNA Cytochrome B Gene (MTCYB) in a Patient with Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke like Episodes Syndrome (P02.088)
CONCLUSIONS: This case demonstrates that MTCYB must be included in the already long list of mitochondrial DNA genes that have been associated with the MELAS phenotype.Supported by: Grant from the National Institutes of Health (HD32062) and by the Marriott Mitochondrial Disorder Clinical Research Fund (MMDCRF). PGR is supported by a postdoctoral fellowship from Ministerio de Educacion y Ciencia, Spain.Disclosure: Dr. Emmanuele has nothing to disclose. Dr. Sotiriou has nothing to disclose. Dr. Gutierrez Rios has nothing to disclose. Dr. Ganesh has nothing to disclose. Dr. Ichord has nothing to disclose. Dr. Foley has nothing...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Emmanuele, V., Sotiriou, E., Gutierrez Rios, P., Ganesh, J., Ichord, R., Foley, A. R., Akman, O., DiMauro, S. Tags: P02 Child Neurology I Source Type: research
Correlation of Atrial Septal Defect Size as Measured by Intracardiac Echocardiography and Transcranial Doppler Ultrasound in Children and Young Adults (P02.102)
CONCLUSIONS: Curtain result on TCD bubble studies is associated with significantly larger ASDs and other cardiac abnormalities in children and young adults.Disclosure: Dr. Doan has nothing to disclose. Dr. Barreto has nothing to disclose. Dr. Fulep has nothing to disclose. Dr. Bui has nothing to disclose. Dr. Butler has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Doan, D., Barreto, A., Fulep, E., Bui, T.-T., Butler, I. Tags: P02 Child Neurology I Source Type: research
Defining the Border-Zone between Episodic Migraine (EM) and Chronic Migraine (CM): Medical Comorbidities in the US Population (P03.110)
CONCLUSIONS: The comorbidity profiles of HFEM have much more in common with CM than with LFEM suggesting that HFEM and CM may bear a close biological relationship.Supported by: The American Migraine Prevalence and Prevention Study is funded through a research grant to the National Headache Foundation from Ortho-McNeil Neurologics, Inc., Titusville, NJ. Additional analyses were supported by a grant from Allergan Inc., Irvine, CA, to the National Headache Foundation. Abstract development was conducted independent of financial support.Disclosure: Dr. Serrano has received research support from Allergan, ENDO Pharmaceuticals, M...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Serrano, D., Buse, D., Reed, M., Pavlovic, J., Vollbracht, S., Sollars, C. M., Lipton, R. Tags: P03 Headache: Epidemiology Source Type: research
High Frequency of Incidental Angiographic Abnormalities in RCVS: Implications For Pathophysiology? (P03.164)
CONCLUSIONS: RCVS is associated with a high frequency of angiographic abnormalities such as cerebral artery dissection. Further studies are warranted to determine whether these reflect a subtle underlying structural abnormality that lowers the threshold for RCVS.Disclosure: Dr. Kursun has nothing to disclose. Dr. Singhal has received personal compensation as an expert witness in medicolegal cases involving stroke in young adults. Dr. Singhal's wife is an employee of Vertex Pharmaceuticals, Inc. Dr. Singhal has received research support from Pfizer and Photothera, Inc.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Kursun, O., Singhal, A. Tags: P03 Cerebrovascular Disease III Source Type: research
Determinants of White Matter Hyperintensity Burden in Patients with Fabry Disease (P03.171)
CONCLUSIONS: In FD subjects, the severity of cerebrovascular disease manifested by MRI-detectable WMH is greater than that of general population. WMH burden is associated with CMP in this cohort independently of age, and it may be affected by different disease processes in men and women and at different disease stages. Further studies exploring associations between WMHV, ERT, age- and gender-specific characteristics, as well as longitudinal WMH progression are warranted.Supported by: Genzyme, Sanofi Company; NIH-NINDS K23NS064052.Disclosure: Dr. Rost has received personal compensation for activities with Genzyme Corporatio...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Rost, N., Metterville, D., Cloonan, L., Fitzpatrick, K., Kanakis, A., Politei, J., Sims, K. Tags: P03 Cerebrovascular Disease III Source Type: research
Epidemiology of the Reversible Cytotoxic Edema of the Splenium of the Corpus Callosum: A Midwest Tertiary Center Experience (P03.198)
CONCLUSIONS: The prevalence of CESCC in the adult patient population at KUMC is rare. It has no gender predilection. In adults, it occurs between 20 to 60 years of age, typically presenting with alteration in mental status and associated headache. The lesions may last 1 to 4 weeks before completely resolving.Disclosure: Dr. Toma has nothing to disclose. Dr. Gronseth has received personal compensation for activities with Boehringer Ingelheim Pharmaceuticals, Inc as a speaker. Dr. Gronseth has received personal compensation in an editorial capacity for Neurology. Dr. Gronseth has received research support from the American Academy of Neurology.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Toma, H., Gronseth, G. Tags: P03 Cerebrovascular Disease III Source Type: research
Cystatin C as a Marker of Degeneration in Multiple Sclerosis (P03.241)
CONCLUSIONS: Cystatin C concentration decrease in RR form of MS could give evidence for high disease activity in this stage of the disease with high myelin damage and neurodegeneration.Supported by: Grant IGA MHCZ NT 12221-5/2010.Disclosure: Dr. Prikrylová Vranová has nothing to disclose. Dr. Sládková has nothing to disclose. Dr. Mares has nothing to disclose. Dr. Hlustík has nothing to disclose. Dr. Langová has nothing to disclose. Dr. Kanovsky has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Prikrylova Vranova, H., Sladkova, V., Mares, J., Hlustik, P., Langova, J., Kanovsky, P. Tags: P03 Multiple Sclerosis: Disease Biomarkers Source Type: research
Pseudo-Hyperdense Middle Cerebral Artery in HSV Encephalitis (P02.025)
CONCLUSIONS: A hyperdense middle cerebral artery 'sign' can be associated with acute thrombus1, but several conditions (including encephalitis related cerebral edema) can give the appearance of a 'pseudo'-hyperdense MCA 'sign'.2 REFERENCES 1. Barber PA, Demchuk AM, Hudon ME, Pexman JH, Hill MD, Buchan AM. Hyperdense sylvian fissure MCA "dot" sign: A CT marker of acute ischemia. Stroke. 2001 Jan;32(1):84-8. 2. Jha B, Kothari M. Pearls & oy-sters: hyperdense or pseudohyperdense MCA sign: a Damocles sword? Neurology. 2009 Jun 9;72(23):e116-7.Disclosure: Dr. Kenmuir has nothing to disclose. Dr. Totoraitis has nothing to di...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Kenmuir, C., Totoraitis, R., Jovin, T., Jadhav, A. Tags: P02 Cerebrovascular Disease II Source Type: research
A Case Report of Dihydroergotamine Administration for Status Migrainosus in a Patient on Longstanding Citalopram Causing a Fatal Reversible Cerebral Vasoconstriction Syndrome (RCVS) (P02.027)
CONCLUSIONS: We report this case report of fatal RCVS of a patient on long standing citalopram who developed this after being administered Dihydroergotamine for status migrainosus. As this is thought to be a self-limiting in terms of clinical features. However, some patients may have more severe focal neurologic symptoms and signs, including ischemic or hemorrhagic strokes as described in our patient.Disclosure: Dr. Asi has nothing to disclose. Dr. Gomes has nothing to disclose. Dr. Dani has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Asi, K., Gomes, J., Dani, D. Tags: P02 Cerebrovascular Disease II Source Type: research
Risk Factors for Cerebral Venous Sinus Thrombisis in the past Five Years at Hahnemann University Hospital (P02.036)
CONCLUSIONS: In our case series 83% of patients had at least one risk factor. In the largest case series, a risk factor was identified 80% of the time. Headache was the most common presenting symptom of CVST. 60% of our patients presented with headache as their chief complaint, which is consistent with the largest case series where 70% of patients presented with a headache. Although papilledema is often thought to be a common finding, only 13% of our patients had this finding. However, in the largest case series to date 30% of people had papilledema. CVST needs to be considered in the differential diagnosis of headaches ev...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Fayyaz, T., Venkatesh, Y., Koenigsberg, R. Tags: P02 Cerebrovascular Disease II Source Type: research
SMART Syndrome (Stroke-Like Migraine Attacks after Radiation Therapy) in Adult and Pediatric Patients (P03.007)
CONCLUSIONS: SMART syndrome appears to be a reversible and recurrent long term complication of cranial irradiation. A review of the data indicates that age and gender may play a role in the development of the disease. Additionally, we postulate other mechanisms of SMART syndrome including possible genetic and hormonal influences.Disclosure: Dr. Armstrong has nothing to disclose. Dr. DiMario has received personal compensation for activities with E-Pocrates.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Armstrong, A., DiMario, F. Tags: P03 Child Neurology II Source Type: research
