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Intravenous insulin treatment in acute stroke: a systematic review and meta‐analysis of randomized controlled trials
ConclusionsThis meta‐analysis of randomized controlled trials does not support the use of intravenous insulin in hyperglycemic stroke patients to improve mortality or functional outcome. The risk of hypoglycemia is increased, however.
Source: International Journal of Stroke - December 30, 2013 Category: Neurology Authors: G. Ntaios, V. Papavasileiou, A. Bargiota, K. Makaritsis, P. Michel Tags: Systematic review Source Type: research

Quality in Acute Stroke Care (QASC): process evaluation of an intervention to improve the management of fever, hyperglycemia, and swallowing dysfunction following acute stroke
BackgroundOur randomized controlled trial of a multifaceted evidence‐based intervention for improving the inpatient management of fever, hyperglycemia, and swallowing dysfunction in the first three‐days following stroke improved outcomes at 90 days by 15%. We designed a quantitative process evaluation to further explain and illuminate this finding. MethodsBlinded retrospective medical record audits were undertaken for patients from 19 stroke units prior to and following the implementation of three multidisciplinary evidence‐based protocols (supported by team‐building workshops, and site‐based education and suppor...
Source: International Journal of Stroke - December 1, 2013 Category: Neurology Authors: Peta Drury, Christopher Levi, Catherine D'Este, Patrick McElduff, Elizabeth McInnes, Jennifer Hardy, Simeon Dale, N Wah Cheung, Jeremy M Grimshaw, Clare Quinn, Jeanette Ward, Malcolm Evans, Dominique Cadilhac, Rhonda Griffiths, Sandy Middleton Tags: Research Source Type: research

Management of fever, hyperglycemia, and swallowing dysfunction following hospital admission for acute stroke in New South Wales, Australia
ConclusionsOur results showed that acute stroke patients were: undermonitored and undertreated for fever and hyperglycemia; and underscreened for swallowing dysfunction and unnecessarily reassessed by a speech pathologist, indicating the need for urgent behavior change.
Source: International Journal of Stroke - November 10, 2013 Category: Neurology Authors: Peta Drury, Christopher Levi, Elizabeth McInnes, Jennifer Hardy, Jeanette Ward, Jeremy M. Grimshaw, Catherine D' Este, Simeon Dale, Patrick McElduff, N Wah Cheung, Clare Quinn, Rhonda Griffiths, Malcolm Evans, Dominique Cadilhac, Sandy Middleton Tags: Research Source Type: research

The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial protocol: a randomized, blinded, efficacy trial of standard vs. intensive hyperglycemia management in acute stroke
DiscussionThis trial will provide important novel information about preferred management of acute ischemic stroke patients with hyperglycemia. It will determine the potential benefits and risks of intensive glucose control during acute stroke.
Source: International Journal of Stroke - March 19, 2013 Category: Neurology Authors: Askiel Bruno, Valerie L. Durkalski, Christiana E. Hall, Rattan Juneja, William G. Barsan, Scott Janis, William J. Meurer, Amy Fansler, Karen C. Johnston, Tags: Protocol Source Type: research