• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Is acute reperfusion therapy safe in acute ischemic stroke patients who harbor unruptured intracranial aneurysm?
ConclusionOur findings suggest that neither intravenous thrombolysis nor combination of intravenous and intra‐arterial thrombolysis increases the risk of aneurysmal hemorrhage in acute ischemic stroke patients who harbor unruptured intracranial aneurysms less than 10 mm in diameter. Their listing in exclusion criteria for intravenous thrombolysis should be reconsidered to assure appropriate use of acute reperfusion therapy in this group of patients.
Source: International Journal of Stroke - September 17, 2015 Category: Neurology Authors: Ashkan Mowla, Karanbir Singh, Sandhya Mehla, Mohammad K. Ahmed, Peyman Shirani, Haris Kamal, Chandan Krishna, Robert N. Sawyer, Marilou Ching, Adnan H. Siddiqui, Elad I. Levy, Kenneth V. Snyder, Annemarie Crumlish, L. N. Hopkins Tags: Research Source Type: research

One‐year case fatality rate following stroke in the Mashhad Stroke Incidence Study: a population‐based study of stroke in Iran
ConclusionDespite the younger age of stroke occurrence in Iran, the one‐year case fatality rate following stroke is similar to that reported in developed countries.
Source: International Journal of Stroke - August 26, 2015 Category: Neurology Authors: Ali Shoeibi, Maryam Salehi, Amanda G. Thrift, Moira K. Kapral, Mohammad Taghi Farzadfard, Amir Azarpazhooh, Parvaneh Layegh, Peyman Hashemi, Amin Amiri, Naghmeh Mokhber, Bahare Hassankhani, Mahmoud Reza Azarpazhooh Tags: Research Source Type: research

Direct medical cost of stroke in Singapore
ConclusionThere is a considerable economic burden associated with stroke in Singapore. The type of stroke, length of poststroke period, and stroke complications and comorbidities are found to be associated with the total costs. Efforts to reduce inpatient costs and to allocate health resources to focus on the primary prevention of stroke should become a priority.
Source: International Journal of Stroke - July 14, 2015 Category: Neurology Authors: Charmaine Shuyu Ng, Matthias Paul Han Sim Toh, Jiaying Ng, Yu Ko Tags: Research Source Type: research

Canadian Stroke Best Practice Recommendations: Hyperacute Stroke Care Guidelines, Update 2015
The 2015 update of the Canadian Stroke Best Practice Recommendations Hyperacute Stroke Care guideline highlights key elements involved in the initial assessment, stabilization, and treatment of patients with transient ischemic attack (TIA), ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, and acute venous sinus thrombosis. The most notable change in this 5th edition is the addition of new recommendations for the use of endovascular therapy for patients with acute ischemic stroke and proximal intracranial arterial occlusion. This includes an overview of the infrastructure and resources required ...
Source: International Journal of Stroke - July 6, 2015 Category: Neurology Authors: Leanne K. Casaubon, Jean‐Martin Boulanger, Dylan Blacquiere, Scott Boucher, Kyla Brown, Tom Goddard, Jacqueline Gordon, Myles Horton, Jeffrey Lalonde, Christian LaRivière, Pascale Lavoie, Paul Leslie, Jeanne McNeill, Bijoy K. Menon, Brian Moses, Melani Tags: Guidelines Source Type: research

Statins and subarachnoid hemorrhage in Medicare patients with unruptured cerebral aneurysms
ConclusionsStatin use by patients with unruptured cerebral aneurysms was not associated with subarachnoid hemorrhage risk. Given the prior animal experimental studies demonstrating a protective effect, further prospective studies are needed to investigate the potential relationship.
Source: International Journal of Stroke - June 29, 2015 Category: Neurology Authors: Kimon Bekelis, Jeremy Smith, Weiping Zhou, Todd A. MacKenzie, David W. Roberts, Jonathan Skinner, Nancy E. Morden Tags: Research Source Type: research

Nosocomial infections after aneurysmal subarachnoid hemorrhage: time course and causative pathogens
ConclusionNosocomial infections after subarachnoid hemorrhage are common and mostly occur in the first week after ictus. Future studies should investigate if general hygienic measures, infection awareness, minimizing the duration of mechanical ventilation and use of catheters/drains, or prophylactic antibiotics reduce infections and improve functional outcome.
Source: International Journal of Stroke - April 1, 2015 Category: Neurology Authors: Kamil G. Laban, Gabriel J. E. Rinkel, Mervyn D. I. Vergouwen Tags: Research Source Type: research

Carotid intima‐media thickness – a potential predictor for rupture risk of intracranial aneurysms
ConclusionThere is an association between IMT and intracranial aneurysm rupture status at the time of aneurysm treatment. Carotid IMT can be a potential predictor of aneurysm rupture. IMT may thus be a possible adjunct in the risk assessment of aneurysm rupture, and a helpful tool in patient risk stratification and counseling.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Marianne Lundervik, Annette Fromm, Øystein Ariansen Haaland, Ulrike Waje‐Andreassen, Frode Svendsen, Lars Thomassen, Christian A. Helland Tags: Research Source Type: research

Program for the epidemiological evaluation of stroke in Tandil, Argentina (PREVISTA) study: rationale and design
The availability of population‐based epidemiological data on the incident risk of stroke is very scarce in Argentina and other Latin American countries. In response to the priorities established by the World Health Organization and the United Nations, PREVISTA was envisaged as a population‐based program to determine the risk of first‐ever and recurrent stroke and transient ischemic attack incidence and mortality in Tandil, Buenos Aires, Argentina. The study will be conducted according to Standardized Tools for Stroke Surveillance (STEPS Stroke) methodology and will enroll all new (incident) and recurrent consecutive ...
Source: International Journal of Stroke - September 11, 2013 Category: Neurology Authors: Luciano A. Sposato, Mariano L. Coppola, Juan Altamirano, Brenda Borrego Guerrero, Jorge Casanova, Maximiliano De Martino, Alejandro Díaz, Valery L. Feigin, Fernando Funaro, María E. Gradillone, María L. Lewin, Renato D. Lopes, Daniel H. López, Mariel Tags: Protocol Source Type: research

HIMALAIA (Hypertension Induction in the Management of AneurysmaL subArachnoid haemorrhage with secondary IschaemiA): a randomized single‐blind controlled trial of induced hypertension vs. no induced hypertension in the treatment of delayed cerebral ischemia after subarachnoid hemorrhage
This article describes the design of the HIMALAIA trial (Hypertension Induction in the Management of AneurysmaL subArachnoid haemorrhage with secondary IschaemiA), designed to assess the effectiveness of induced hypertension on neurological outcome in patients with DCI after SAH. AimsTo investigate whether induced hypertension improves the functional outcome in patients with delayed cerebral ischemia after SAH. DesignThe HIMALAIA trial is a multicenter, singe‐blinded, randomized controlled trial in patients with DCI after a recent SAH. Eligible patients will be randomized to either induced hypertension (n = 120) or t...
Source: International Journal of Stroke - May 22, 2013 Category: Neurology Authors: C. S. Gathier, W. M. Bergh, A. J. C. Slooter, Tags: Protocols Source Type: research

Differences in neuropsychological profiles of long‐term intracerebral hemorrhage and subarachnoid hemorrhage survivors
Source: International Journal of Stroke - May 20, 2013 Category: Neurology Authors: Suzanne Barker‐Collo, Valery Feigin, Rita Krishmnamurthi Tags: Letter to the editor Source Type: research

Cerebral CT perfusion in patients with perimesencephalic and those with aneurysmal subarachnoid hemorrhage
ConclusionsPerimesencephalic hemorrhage patients have a higher cerebral blood flow than aneurysmal subarachnoid hemorrhage patients. The findings of this study further support a venous origin of bleeding in perimesencephalic hemorrhage patients. Future studies should further elaborate on cerebral blood flow in posterior circulation aneurysms.
Source: International Journal of Stroke - March 21, 2013 Category: Neurology Authors: Charlotte H. P. Cremers, Irene C. Schaaf, Jan Willem Dankbaar, Birgitta K. Velthuis, Gabriel J. E. Rinkel Tags: Research Source Type: research

Age‐ and gender‐specific time trend in risk of death of patients admitted with aneurysmal subarachnoid hemorrhage in the Netherlands
ConclusionsThe decrease in risk of death for patients admitted in the Netherlands with subarachnoid hemorrhage is overall considerable, but unevenly distributed over age and gender. Further research should focus on reasons for improved survival (improved diagnostics, improved treatment) and reasons why improvement has not occurred for women and for patients in older age categories.
Source: International Journal of Stroke - March 12, 2013 Category: Neurology Authors: Dennis J. Nieuwkamp, Ilonca Vaartjes, Ale Algra, Michiel L. Bots, Gabriël J. E. Rinkel Tags: Research Source Type: research

Type of admission is associated with outcome of spontaneous subarachnoid hemorrhage
ConclusionsSpontaneous subarachnoid hemorrhage patients admitted directly to our comprehensive stroke center showed less complications compared to those transferred from general hospitals. This improvement was independent of time to treatment. Additional research in multiple centers using prospective analysis should be conducted to confirm that preferential direct transport to a comprehensive stroke center would likely yield considerable improvements in public health.
Source: International Journal of Stroke - March 12, 2013 Category: Neurology Authors: Doniel Drazin, Jack Rosner, Miriam Nuño, Michael J. Alexander, Wouter I. Schievink, David Palestrant, Patrick D. Lyden, Chad Miller Tags: Research Source Type: research