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Non ‐persistence in ischaemic stroke: Risk of recurrent vascular events
ConclusionAfter a long follow‐up period, ischaemic stroke patients with a high vascular risk profile who stopped taking their secondary preventive medication had an increased risk of a recurrent vascular events.
Source: Acta Neurologica Scandinavica - December 8, 2017 Category: Neurology Authors: M. Rijkmans, G. de Jong, J. S. P. van den Berg Tags: ORIGINAL ARTICLE Source Type: research

Life situation 5  years after subarachnoid haemorrhage
ConclusionsIn this 5‐year follow‐up after SAH, the participants reported to have a greater number of hidden disabilities compared to physical problems, whereas most had acceptable participation in society. A yearly follow‐up after a SAH could be suggested aiming to improving the cognitive and mental health.
Source: Acta Neurologica Scandinavica - September 4, 2017 Category: Neurology Authors: H. C. Persson, L. Carlsson, K. S. Sunnerhagen Tags: ORIGINAL ARTICLE Source Type: research

Small vessel disease and clinical outcomes after IV rt ‐PA treatment
ConclusionOur results suggest that SVD negatively affects stroke outcomes after intravenous thrombolysis. Although white matter changes seem to be the major driver in relation to worse outcomes, global estimation of SVD is feasible and may provide helpful information.
Source: Acta Neurologica Scandinavica - February 24, 2017 Category: Neurology Authors: F. Arba, D. Inzitari, M. Ali, S. J. Warach, M. Luby, K. R. Lees, Tags: ORIGINAL ARTICLE Source Type: research

Subjective health complaints predict functional outcome six months after stroke
ConclusionsInitial stroke severity was the main predictor of functional outcome. Subjective health complaints score was a potent predictor for both outcome and improvement from baseline to 6 months and at the same time ameliorated the predictive impact of sex. The poorer functional prognosis for women after stroke may therefore be related to their higher load of subjective health complaints rather than to their sex itself. Treating these complaints may possibly improve the functional prognosis.
Source: Acta Neurologica Scandinavica - June 27, 2016 Category: Neurology Authors: H. Hofstad, H. Næss, B. E. B. Gjelsvik, G. E. Eide, J. S. Skouen Tags: Original Article Source Type: research

Acute ischemic stroke and abnormal blood hemoglobin concentration
ConclusionsOur results suggest that an elevated HGB on the initial admission is associated with more severe strokes, greater disability at discharge, and higher 30‐day mortality after AIS. A low HGB on admission is associated with longer stay in the acute care hospital.
Source: Acta Neurologica Scandinavica - October 21, 2015 Category: Neurology Authors: J. C. Furlan, J. Fang, F. L. Silver Tags: Original Article Source Type: research

CSF tau correlates with CJD disease severity and cognitive decline
ConclusionThe correlation between tau levels and the disease severity and degree of cognitive decline in patients with fCJD suggests that tau can be a biomarker reflecting the extent of neuronal damage.
Source: Acta Neurologica Scandinavica - May 25, 2015 Category: Neurology Authors: O. S. Cohen, J. Chapman, A. D. Korczyn, N. Warman‐Alaluf, Z. Nitsan, S. Appel, E. Kahana, H. Rosenmann Tags: Original Article Source Type: research

Case‐fatality and disability in the Tanzanian Stroke Incidence Project cohort
ConclusionsCase‐fatality rates are higher than reported in high‐income countries, with post‐stroke disability a significant predictor of death. Sustainable interventions to reduce post‐stroke disability in this setting should be investigated.
Source: Acta Neurologica Scandinavica - May 5, 2015 Category: Neurology Authors: R. W. Walker, K. Wakefield, W. K. Gray, A. Jusabani, M. Swai, F. Mugusi Tags: Original Article Source Type: research

Stroke treated at a neurosurgical ward: a cohort study
ConclusionsPatients with stroke who were admitted to a neurosurgical ward had a low mortality rate during the acute treatment, and at 4 years post‐stroke, the survival rate was 75%. The level of disability and dependence at discharge was high, but at 4 years post‐stroke, there was both measurable and self‐perceived improvement in function.
Source: Acta Neurologica Scandinavica - March 27, 2015 Category: Neurology Authors: K. Vikholmen, H. C. Person, K. S. Sunnerhagen Tags: Original Article Source Type: research

Outcome of men and women after atrial fibrillation and stroke
ConclusionsThere were no gender differences in long‐term mortality after stroke related to AF. Men were significantly more often prescribed anticoagulants before stroke, a finding that indicates the need for further studies.
Source: Acta Neurologica Scandinavica - February 1, 2015 Category: Neurology Authors: A.‐C. Jönsson, J. Ek, C. Kremer Tags: Original Article Source Type: research

Depression, anxiety, and cognitive functioning after intracerebral hemorrhage
ConclusionsOne of four survivors of ICH at young age suffers long‐term PSD. Higher degree of disability predicted occurrence of PSD. Treatment of depression appears as an unmet need in young ICH survivors.
Source: Acta Neurologica Scandinavica - January 30, 2015 Category: Neurology Authors: R.‐J. Koivunen, H. Harno, T. Tatlisumak, J. Putaala Tags: Original Article Source Type: research

Burden and cost of neurological diseases: a European North–South comparison
ConclusionsHealth expenditure, YLDs, costs and prevalence of neurological conditions were generally not correlated across the eight countries. A clear North–South gradient was found for health expenditures, and partially for YLDs, costs and diseases' prevalence. We hypothesized that this is a consequence of the expansion of morbidity of neurological conditions connected to ageing, that health and welfare systems of selected countries were not prepared to face.
Source: Acta Neurologica Scandinavica - October 23, 2014 Category: Neurology Authors: A. Raggi, M. Leonardi Tags: Original Article Source Type: research

Correlation of post‐stroke fatigue with glucose, homocysteine and functional disability
ConclusionsThe serum glucose and Hcy levels and functional disability are closely related to fatigue during the acute stage of ischaemic stroke.
Source: Acta Neurologica Scandinavica - October 13, 2014 Category: Neurology Authors: D. Wu, L. Wang, W. Teng, K. Huang, X. Shang Tags: Original Article Source Type: research

Changing clinical patterns and increasing prevalence in CADASIL
ConclusionsCADASIL prevalence is at least 4.6 per 100,000 adults. Median age of first stroke may be older than previously thought. Clinicians should consider CADASIL in the differential diagnosis even in older patients with stroke.
Source: Acta Neurologica Scandinavica - April 1, 2014 Category: Neurology Authors: F. C. Moreton, S. S. M. Razvi, R. Davidson, K. W. Muir Tags: Original Article Source Type: research

Routine serum C‐reactive protein and stroke outcome after intravenous thrombolysis
ConclusionsAccording to our findings, elevated routine serum CRP measured within 24 h after admission does not seem to independently affect the outcome in patients receiving intravenous thrombolysis for stroke. However, further studies of blood samples taken directly before the treatment are needed.
Source: Acta Neurologica Scandinavica - February 20, 2014 Category: Neurology Authors: M. Karlinski, J. Bembenek, K. Grabska, A. Kobayashi, A. Baranowska, T. Litwin, A. Czlonkowska Tags: Original Article Source Type: research

Association between neurological disorders, functioning, and mortality in the elderly
ConclusionsWe found that not only specific neurological disorders, but also earlier symptoms are related to impaired functioning and predict mortality in the elderly. These findings have potential clinical relevance for screening and early detection of individuals at risk.
Source: Acta Neurologica Scandinavica - February 3, 2014 Category: Neurology Authors: M. E. Czira, B. T. Baune, A. Roesler, K. Pfadenhauer, C. Trenkwalder, K. Berger Tags: Original Article Source Type: research

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