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Optimal therapeutic conditions for the neural stem cell-based management of ischemic stroke: a systematic review and network meta-analysis based on animal studies
This study aimed ...
Source: BMC Neurology - September 13, 2022 Category: Neurology Authors: Yongna Yang, Xurui Hu, Qijie Qin, Fanling Kong, Xiaolan Peng, Jing Zhao, Jianghua Si, Zhilong Yang and Shoupin Xie Tags: Research Source Type: research

Efficacy of adipose derived stem cells on functional and neurological improvement following ischemic stroke: a systematic review and meta-analysis
The evidence on the efficacy of adipose derived stem cells (ADSCs) in the treatment of stroke is controversial. Therefore, the aim of present systematic review and meta-analysis is to evaluate the efficacy of ...
Source: BMC Neurology - August 10, 2020 Category: Neurology Authors: Mahmoud Yousefifard, Jebreil Shamseddin, Asrin Babahajian and Arash Sarveazad Tags: Research article Source Type: research

Research on advanced intervention using novel bone marrOW stem cell (RAINBOW): a study protocol for a phase I, open-label, uncontrolled, dose-response trial of autologous bone marrow stromal cell transplantation in patients with acute ischemic stroke
Stroke is a leading cause of death and disability, and despite intensive research, few treatment options exist. However, a recent breakthrough in cell therapy is expected to reverse the neurological sequelae o...
Source: BMC Neurology - September 8, 2017 Category: Neurology Authors: Hideo Shichinohe, Masahito Kawabori, Hiroaki Iijima, Tuyoshi Teramoto, Takeo Abumiya, Naoki Nakayama, Ken Kazumata, Shunsuke Terasaka, Teruyo Arato and Kiyohiro Houkin Tags: Study protocol Source Type: research

Higher numbers of circulating endothelial progenitor cells in stroke patients with intracranial arterial stenosis
Background: Bone marrow-derived endothelial stem cells participate in vascular repairs. Numbers of circulating endothelial progenitor cells (cEPCs) are associated with atherosclerosis. Fibrinogen plays a key role in atherosclerosis. Objective was to assess if cEPC counts were associated with atherosclerotic intracranial artery stenosis (IAS). Methods: Three hundred subjects (108 patients with stroke and IAS (IAS), 120 control patients with stroke without IAS (CP), and 72 healthy controls (HC)) were retrospectively analyzed. cEPCs were identified and counted by flow cytometry using CD34, CD133 and KDR. Plasma fibrinogen was...
Source: BMC Neurology - November 5, 2013 Category: Neurology Authors: Zhizhong LiuXiurong DingFang FangRuimin WangYan ChenYuetao MaGuojun ZhangXixiong Kang Source Type: research