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Source: Epilepsy Curr

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Total 106 results found since Jan 2013.

Sleep-Wake Disorders in Stroke-Increased Stroke Risk and Deteriorated Recovery? An Evaluation on the Necessity for Prevention and Treatment.
Abstract PURPOSE OF REVIEW: Sleep-wake disorders (SWD) are common not only in the general population but also in stroke patients, in whom SWD may be pre-existent or appear "de novo" as a consequence of brain damage. Despite increasing evidence of a negative impact of SWD on cardiocerebrovascular risk, cognitive functions, and quality of life, SWD are insufficiently considered in the prevention and management of patients with stroke. This narrative review aims at summarizing the current data on the bidirectional link between SWD and stroke. RECENT FINDINGS: Several studies have demonstrated that sleep-disorder...
Source: Epilepsy Curr - September 7, 2018 Category: Neurology Authors: Duss SB, Brill AK, Bargiotas P, Facchin L, Alexiev F, Manconi M, Bassetti CL Tags: Curr Neurol Neurosci Rep Source Type: research

Improving cognitive outcomes for pediatric stroke.
Abstract PURPOSE OF REVIEW: The past 20 years have seen a 35% increase in prevalence of pediatric stroke. Contrary to widely held views, children do not recover better than adults. This review explores the impact of pediatric stroke on cognitive domains, including intellectual and executive functions, memory and behavior, and the influence of age, lesion characteristics, and comorbidities on outcome. RECENT FINDINGS: Cognitive problems occur in up to half of ischemic and hemorrhagic stroke survivors. Single-center studies have shown intelligence quotient scores skewed to the lower end of the average range, wi...
Source: Epilepsy Curr - January 29, 2017 Category: Neurology Authors: Greenham M, Anderson V, Mackay MT Tags: Curr Opin Neurol Source Type: research

Seven questions about stroke and epilepsy.
Abstract Seizures and stroke are both common neurologic conditions, but when they occur in close temporal proximity they produce much more concern than either does alone. The stroke specialist (and the family) fear that convulsions will worsen the stroke because of acute hypertension and airway compromise, and the epileptologist is concerned that these acute seizures are the harbingers of later epilepsy. Other less commonly recognized but important aspects of this relationship are that subclinical seizures worsen some forms of stroke, and some anticonvulsants may have more adverse effects on stroke patients than t...
Source: Epilepsy Curr - November 1, 2012 Category: Neurology Authors: Bleck TP Tags: Epilepsy Curr Source Type: research

Incidence, Implications, and Management of Seizures Following Ischemic and Hemorrhagic Stroke.
Abstract PURPOSE OF REVIEW: In this review, we summarize the recent literature regarding the incidence and treatment of seizures arising after ischemic and hemorrhagic strokes. Additionally, we identify open questions in guidelines and standard clinical care to aid future studies aiming to improve management of seizures in post-stroke patients. RECENT FINDINGS: Studies demonstrate an increasing prevalence of seizures following strokes, probably a consequence of advances in post-stroke management and expanding use of continuous EEG monitoring. Post-stroke seizures are associated with longer hospitalization and...
Source: Epilepsy Curr - May 26, 2019 Category: Neurology Authors: Doria JW, Forgacs PB Tags: Curr Neurol Neurosci Rep Source Type: research

Stroke and Ischemic Heart Disease With Enzyme-inducing Antiseizure Medications: Time to Change Prescribing Habits
Conclusions and Relevance: The hazard of incident cardiovascular disease is higher in those receiving eiASMs. The association is dose dependent and the absolute difference in hazard seems to reach clinical significance by approximately 10 years from first exposure.PMID:35444497 | PMC:PMC8988723 | DOI:10.1177/15357597211070392
Source: Epilepsy Curr - April 21, 2022 Category: Neurology Authors: David G Vossler Source Type: research

LTBP1 Gene Expression in the Cerebral Cortex and Its Neuroprotective Mechanism in Mice with Postischemic Stroke Epilepsy
CONCLUSION: LTBP1 can affect the changes in inflammation-related pathways by activating TGFβ/SMAD signaling pathway, stimulate the development of epilepsy, and the inhibition of LTBP1 expression can control the occurrence of epilepsy, with neuroprotection.PMID:35676846 | DOI:10.2174/1389201023666220608091511
Source: Epilepsy Curr - June 9, 2022 Category: Neurology Authors: Bo Liu Yan Wang Dongruo He Guochao Han Hao Wang Yuan Lin Tianyu Zhang Chao Yi Hui Li Source Type: research

Epilepsy in Cerebrovascular Diseases: A Narrative Review
CONCLUSION: Some aspects of ES and PSE have been well explored, particularly epidemiology and risk factors. On the contrary, few data exist on physiopathology, and existing evidence is mainly based on studies on animal models. Little is also known on seizure semiology, which may also be difficult to interpret by non-epileptologists. Moreover, the therapeutic approach needs standardization as regards indications and the choice of specific ASMs. Future research may help to better elucidate these aspects.PMID:35794769 | DOI:10.2174/1570159X20666220706113925
Source: Epilepsy Curr - July 7, 2022 Category: Neurology Authors: S Neri S Gasparini A Pascarella D Santangelo V Cianci A Mamm ì M Lo Giudice E Ferlazzo U Aguglia Source Type: research

Management of Neurologic Manifestations in Patients with Liver Disease.
Abstract OPINION STATEMENT: Liver disease, both in its acute and chronic forms, can be associated with a wide spectrum of neurologic manifestations, both central and peripheral, ranging in severity from subclinical changes to neurocritical conditions. Neurologists are frequently consulted to participate in their management. In this review, we present an overview of management strategies for patients with hepatic disease whose clinical course is complicated by neurologic manifestations. Type A hepatic encephalopathy (HE), which occurs in acute liver failure, is a neurologic emergency, and multiple measures should b...
Source: Epilepsy Curr - June 19, 2016 Category: Neurology Authors: Ferro JM, Viana P, Santos P Tags: Curr Treat Options Neurol Source Type: research