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Total 186 results found since Jan 2013.

Department of Error Department of Error
ATTEND Collaborative Group. Family-led rehabilitation after stroke in India (ATTEND): a randomised controlled trial. Lancet 2017; 390: 588 –99—In the Summary of this Article, the number of patients lost to follow-up should have been 33. This correction has been made to the online version as of Aug 3, 2017, and the printed Article is correct.
Source: LANCET - August 4, 2017 Category: General Medicine Tags: Department of Error Source Type: research

Correspondence Intensive speech and language therapy after stroke
Caterina Breitenstein and colleagues (April 15, p 1528)1 reported that 3 weeks of intensive speech and language therapy significantly enhanced verbal communication in people aged 70 years or younger with chronic aphasia after stroke. The primary outcome measure was assessed using the Amsterdam-Nijmegen Everyday Language Test (ANELT) A-scale, and the mean difference of the ANELT A-scale score improved 2 ·61 (SD 4·94) points from baseline to after intensive speech and language therapy, but not from baseline to after treatment deferral.
Source: LANCET - July 14, 2017 Category: General Medicine Authors: Ryo Sakamoto, Asaka Higuchi, Kenji Tsuda, Tetsuya Tanimoto, Masahiro Kami Tags: Correspondence Source Type: research

Correspondence Intensive speech and language therapy after stroke – Authors' reply
We thank Ryo Sakamoto and colleagues for their Correspondence regarding our FCET2EC trial on the effectiveness of intensive speech and language therapy in chronic post-stroke aphasia.1 Their point regarding the minimal clinically important difference of the primary outcome measure (Amsterdam-Nijmegen Everyday Language Test [ANELT] A-scale) is of major concern, as already acknowledged in our Article ( “To our knowledge, no previously published studies exist on the association of change in ANELT scores with clinical effect.”).
Source: LANCET - July 14, 2017 Category: General Medicine Authors: Caterina Breitenstein, Peter Martus, Klaus Willmes, Wolfram Ziegler, Annette Baumgaertner Tags: Correspondence Source Type: research

Comment Building evidence for care beyond the medical centre
Digital health has been defined as the “convergence of the digital and genomic revolutions with health, health care, living, and society”.1 The term is often used interchangeably with mHealth or mobile health because of the central role played by mobile devices. Remote patient monitoring and telemedicine constitute a subset of digita l health technologies that enable monitoring of patients outside conventional clinical settings, such as in the comfort of their own homes. Evidence regarding the efficacy, effectiveness, economics, and clinical preferences of remote patient monitoring and telemedicine is growing in many c...
Source: LANCET - July 14, 2017 Category: General Medicine Authors: Thomas A Ullman, Ashish Atreja Tags: Comment Source Type: research

Correspondence Unmet challenges for rehabilitation after stroke in China
Stroke is an important public health problem in China, and is one of the leading causes of death and disability. About 2  500 000 people have a stroke in China every year, and 70–80% of patients lose the ability to perform routine activities and require care, resulting in an economic burden for both the country and their family.1 Japan has a similar incidence of stroke because of similar ancestry, but outcomes a fter stroke are better in Japan than in China. In Japan, 64·2% of young patients (age
Source: LANCET - July 7, 2017 Category: General Medicine Authors: Tetsuya Asakawa, Liang Zong, Liang Wang, Ying Xia, Hiroki Namba Tags: Correspondence Source Type: research

Seminar Chagas disease
Chagas disease is an anthropozoonosis from the American continent that has spread from its original boundaries through migration. It is caused by the protozoan Trypanosoma cruzi, which was identified in the first decade of the 20th century. Once acute infection resolves, patients can develop chronic disease, which in up to 30 –40% of cases is characterised by cardiomyopathy, arrhythmias, megaviscera, and, more rarely, polyneuropathy and stroke. Even after more than a century, many challenges remain unresolved, since epidemiological control and diagnostic, therapeutic, and prognostic methods must be improved.
Source: LANCET - June 30, 2017 Category: General Medicine Authors: Jos é A Pérez-Molina, Israel Molina Tags: Seminar Source Type: research

Comment Cerebral amyloid angiopathy and implications for atrial fibrillation management
Atrial fibrillation, the most common arrhythmia in adults, will increase in prevalence as the population ages.1 The risk of embolic stroke in atrial fibrillation also increases with age. Treatments for the prevention of embolic stroke include warfarin, direct oral anticoagulant agents, and non-anticoagulation strategies such as left atrial appendage occlusion.1 Current scores to estimate the risk of ischaemic stroke (CHA2DS2-VaSc score) or haemorrhage (HAS-BLED score) help guide intervention, but do not account for cerebral amyloid angiopathy (CAA), a prevalent, but overlooked condition.
Source: LANCET - June 29, 2017 Category: General Medicine Authors: Christopher V DeSimone, Jonathan Graff-Radford, Majd A El-Harasis, Alejandro A Rabinstein, Samuel J Asirvatham, David R Holmes Tags: Comment Source Type: research

Comment Family-delivered rehabilitation services at home: is the glass empty?
In low-income and middle-income countries, meeting inpatient and outpatient rehabilitation needs of stroke survivors with insufficient staff and facility resources is especially challenging. Family-delivered rehabilitation services might be an innovative way to augment intensity of practice.1 The ATTEND Collaborative Group's ATTEND trial,2 published in The Lancet, is to our knowledge the first appropriately powered trial to investigate the effect of family-delivered, home-based rehabilitation intervention for patients with stroke in a low-middle-income country.
Source: LANCET - June 27, 2017 Category: General Medicine Authors: Gert Kwakkel, Erwin E H van Wegen Tags: Comment Source Type: research

Articles Family-led rehabilitation after stroke in India (ATTEND): a randomised controlled trial
Although task shifting is an attractive solution for health-care sustainability, our results do not support investment in new stroke rehabilitation services that shift tasks to family caregivers, unless new evidence emerges. A future avenue of research should be to investigate the effects of task shifting to health-care assistants or team-based community care.
Source: LANCET - June 27, 2017 Category: General Medicine Authors: The ATTEND Collaborative Group Tags: Articles Source Type: research

Correspondence Stroke in ICD-11: the end of a long exile
In 1955, cerebrovascular diseases were reclassified as circulatory system diseases in the 7th edition of the International Classification of Diseases and Related Health Problems (ICD). WHO's idea then was that stroke is a condition affecting blood vessels. This decision to reclassify cerebrovascular diseases seemed contrary to the pathophysiology and symptoms leading to mortality and morbidity, which are those of brain dysfunction. Moreover, the decision deviated from the principle of ischaemia of other organs (such as the intestines, kidneys, and the eye), which were listed under their respective organs in ICD-7.
Source: LANCET - June 16, 2017 Category: General Medicine Authors: Raad Shakir, Bo Norrving Tags: Correspondence Source Type: research

Comment Preventing major gastrointestinal bleeding in elderly patients
Antiplatelet therapy is the most frequently recommended treatment to prevent recurrent ischaemic events in patients who have had an ischaemic stroke, an acute coronary syndrome, or symptomatic peripheral arterial disease. The most frequently used drugs are aspirin or clopidogrel. Most guidelines recommend lifelong intake of antiplatelet therapy. However, randomised trials that have investigated the benefit of antiplatelet therapy had an observation period of between 2 years and 4 years.1 Therefore, we lack data on the long-term benefit and risk of antiplatelet therapy across long time periods, particularly in elderly patients.
Source: LANCET - June 13, 2017 Category: General Medicine Authors: Hans-Christoph Diener Tags: Comment Source Type: research

Department of Error Department of Error
Cohen AJ, Brauer M, Burnett R, et al. Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015. Lancet 2016; 389: 1907 –18—In this Article, the following changes have been made to the supplementary appendix. In table 1, for the Pinault et al11 study, the country, the CEV (Stroke)-Relative Risk (95% CI), and the IHD-Relative Risk (95% CI) have been corrected (p 11); the second Pinault et al11 reference has been c hanged to Thurston et al (2016; p 11); a footnote has been added stating that the indicated data were...
Source: LANCET - May 23, 2017 Category: General Medicine Tags: Department of Error Source Type: research

Seminar The future of atrial fibrillation management: integrated care and stratified therapy
Atrial fibrillation is one of the major cardiovascular health problems: it is a common, chronic condition, affecting 2 –3% of the population in Europe and the USA and requiring 1–3% of health-care expenditure as a result of stroke, sudden death, heart failure, unplanned hospital admissions, and other complications. Early diagnosis of atrial fibrillation, ideally before the first complication occurs, remains a ch allenge, as shown by patients who are only diagnosed with the condition when admitted to hospital for acute cardiac decompensation or stroke.
Source: LANCET - April 28, 2017 Category: General Medicine Authors: Paulus Kirchhof Tags: Seminar Source Type: research

Obituary Peter Mansfield
Nobel Prize winning inventor of magnetic resonance imaging. He was born in London, UK, on Oct 9, 1933, and died in Nottingham, UK, after a stroke on Feb 8, 2017, aged 83 years.
Source: LANCET - April 20, 2017 Category: Journals (General) Authors: Geoff Watts Tags: Obituary Source Type: research