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Total 186 results found since Jan 2013.

Editorial Salt: friend or foe?
Dietary guidelines advise against the consumption of too much salt. A high intake of sodium causes raised blood pressure—an established risk factor for heart disease, stroke, and kidney disease. But how much salt is too much? And could a very low salt intake also be detrimental?
Source: LANCET - May 24, 2013 Category: Journals (General) Authors: The Lancet Tags: Editorial Source Type: research

Editorial Compassionate release in the USA
A man has suffered a massive stroke. The right side of his body is paralysed, he cannot speak, and needs total assistance with activities of daily living. The man is serving a life sentence in a US prison for cocaine and heroin distribution. In 2006, he appealed for early release, but was denied because his life expectancy could not be determined. This case is one of many highlighted in a new report by the US Department of Justice, which concludes that compassionate release programmes in the USA are poorly managed by the Federal Bureau of Prisons.
Source: LANCET - May 10, 2013 Category: Journals (General) Authors: The Lancet Tags: Editorial Source Type: research

Perspectives The singular science of John Snow
John Snow was a scientist of rare dedication, who published more than 100 contributions to the medical literature in a career entirely supported by clinical earnings and terminated by a lethal stroke when he was just 45 years old. The range of clinical and scientific topics covered by his research was wide, although he is most remembered for developing the scientific basis of anaesthesia practice and working out the epidemiology and preventability of cholera. Snow's science was singular in two senses: it was singularly creative and productive; and it reflected a singular, unified scientific approach to the problems he addressed.
Source: LANCET - April 13, 2013 Category: Journals (General) Authors: Nigel Paneth, Paul Fine Tags: Perspectives Source Type: research

Seminar Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy is a common inherited cardiovascular disease present in one in 500 of the general population. It is caused by more than 1400 mutations in 11 or more genes encoding proteins of the cardiac sarcomere. Although hypertrophic cardiomyopathy is the most frequent cause of sudden death in young people (including trained athletes), and can lead to functional disability from heart failure and stroke, the majority of affected individuals probably remain undiagnosed and many do not experience greatly reduced life expectancy or substantial symptoms.
Source: LANCET - January 18, 2013 Category: Journals (General) Authors: Barry J Maron, Martin S Maron Tags: Seminar Source Type: research

Department of Error Department of Error
Lopes RD, Al-Khatib SM, Wallentin L, et al. Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial. Lancet 2012; 380: 1749–58—In table 3 and table 5 of this Article (Nov 17), the %s per person-year in the ischaemic stroke (overall results) row were incorrect. The values should have been 0·84% (apixaban) and 0·82% (warfarin) in both tables. These corrections have been made to the online version as of Jan 18, 2013.
Source: LANCET - January 18, 2013 Category: Journals (General) Authors: The Lancet Tags: Department of Error Source Type: research

World Report India unveils plans to improve stroke research and care
India has begun a nationwide effort to collect stroke data in a bid to improve epidemiological research and care for the disorder. Tamoghna Biswas reports from Kolkata.
Source: LANCET - January 18, 2013 Category: Journals (General) Authors: Tamoghna Biswas Tags: World Report Source Type: research