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Source: Heart
Condition: Heart Disease

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Total 83 results found since Jan 2013.

Subannular repair in secondary mitral regurgitation with restricted leaflet motion during systole
Conclusions Our study demonstrates the safety and feasibility of standardised subannular repair to treat ventricular SMR (Carpentier type IIIb) in a multicentre setting. By addressing mitral leaflet tethering, papillary muscle relocation results in very satisfactory 1-year outcomes and has the potential to durably restore MV geometry; nevertheless, long-term FU is mandatory. Trial registration number NCT03470155.
Source: Heart - August 24, 2023 Category: Cardiology Authors: Pausch, J., Harmel, E., Reichenspurner, H., Kempfert, J., Kuntze, T., Owais, T., Holubec, T., Walther, T., Krane, M., Vitanova, K., Borger, M. A., Eden, M., Hachaturyan, V., Bramlage, P., Falk, V., Girdauskas, E. Tags: Valvular heart disease Source Type: research

Primary prevention of cardiovascular disease in women with a Mediterranean diet: systematic review and meta-analysis
Conclusion This study supports a beneficial effect of the Mediterranean diet on primary prevention of CVD and death in women, and is an important step in enabling sex specific guidelines.
Source: Heart - July 27, 2023 Category: Cardiology Authors: Pant, A., Gribbin, S., McIntyre, D., Trivedi, R., Marschner, S., Laranjo, L., Mamas, M. A., Flood, V., Chow, C. K., Zaman, S. Tags: Editor's choice, Press releases Cardiac risk factors and prevention Source Type: research

Systolic blood pressure, chronic obstructive pulmonary disease and cardiovascular risk
Conclusion Using deep learning for modelling EHR, we identified a monotonic association between SBP and risk of cardiovascular events in patients with COPD.
Source: Heart - July 27, 2023 Category: Cardiology Authors: Rao, S., Nazarzadeh, M., Li, Y., Canoy, D., Mamouei, M., Salimi-Khorshidi, G., Rahimi, K. Tags: Open access Cardiac risk factors and prevention Source Type: research

Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer
Conclusions Cancer history is linked to increased risk of incident CVDs and adverse cardiac remodelling independent of shared vascular risk factors.
Source: Heart - June 14, 2023 Category: Cardiology Authors: Raisi-Estabragh, Z., Cooper, J., McCracken, C., Crosbie, E. J., Walter, F. M., Manisty, C. H., Robson, J., Mamas, M. A., Harvey, N. C., Neubauer, S., Petersen, S. E. Tags: Open access, Editor's choice, Press releases Cardiac risk factors and prevention Source Type: research

Proof of concept study on coronary microvascular function in low flow low gradient aortic stenosis
Conclusions CMD is more severe in patients with LFLGAS compared with NFHGAS and is associated with low-flow state, left atrial dysfunction and reduced cardiac performance.
Source: Heart - April 25, 2023 Category: Cardiology Authors: Scarsini, R., Pighi, M., Mainardi, A., Portolan, L., Springhetti, P., Mammone, C., Della Mora, F., Fanti, D., Tavella, D., Gottin, L., Bergamini, C., Benfari, G., Pesarini, G., Ribichini, F. L. Tags: Valvular heart disease Source Type: research

Lower birth weight is linked to poorer cardiovascular health in middle-aged population-based adults
Conclusions Lower birth weight was associated with greater risk of incident MI and unhealthy LV phenotypes; effects were partially mediated through cardiometabolic disease and systemic inflammation. These findings support consideration of birth weight in risk prediction and highlight actionable areas for disease prevention.
Source: Heart - March 10, 2023 Category: Cardiology Authors: Raisi-Estabragh, Z., Cooper, J., Bethell, M. S., McCracken, C., Lewandowski, A. J., Leeson, P., Neubauer, S., Harvey, N. C., Petersen, S. E. Tags: Open access Cardiac risk factors and prevention Source Type: research

Prevalence, outcomes and costs of a contemporary, multinational population with heart failure
Conclusions We estimate that 1–2% of the contemporary adult population has HF. These individuals are at significant risk of adverse outcomes and associated costs, predominantly driven by hospitalisations for HF or CKD. There is considerable public health potential in understanding the contemporary burden of HF and the importance of optimising its management.
Source: Heart - March 10, 2023 Category: Cardiology Authors: Norhammar, A., Bodegard, J., Vanderheyden, M., Tangri, N., Karasik, A., Maggioni, A. P., Sveen, K. A., Taveira-Gomes, T., Botana, M., Hunziker, L., Thuresson, M., Banerjee, A., Sundström, J., Bollmann, A. Tags: Open access, Press releases Heart failure and cardiomyopathies Source Type: research

Early surgical intervention versus conservative management of asymptomatic severe aortic stenosis: a systematic review and meta-analysis
Conclusions This study suggests that for patients with asymptomatic severe AS an early surgical intervention compared with a conservative WW strategy was associated with a lower heart failure hospitalisation and a similar rate of stroke or myocardial infarction, although with significant risk of bias. PROSPERO registration number CRD42021291144.
Source: Heart - January 27, 2023 Category: Cardiology Authors: Costa, G. N. F., Cardoso, J. F. L., Oliveiros, B., Goncalves, L., Teixeira, R. Tags: Valvular heart disease Source Type: research

Heartbeat: hospitalisation for COVID-19 is associated with an increased risk of subsequent adverse cardiovascular events
In order to assess whether previous COVID-19 infection might be associated with a higher risk of subsequent adverse cardiovascular disease (CVD) events, Raisi-Estabragh and colleagues1 analysed incident CVD events in 17 871 UK Biobank cases with prospective follow-up from March 2020 to March 2021. Hospitalisation for COVID-19 was associated with an increased risk of several adverse CVD events, including myocardial infarction, stroke, heart failure, atrial fibrillation, venous thromboembolism and mortality (figure 1). Risk was highest in the first 30 days after infection, but remained higher than matched controls over an av...
Source: Heart - December 22, 2022 Category: Cardiology Authors: Otto, C. M. Tags: COVID-19 Highlights from this issue Source Type: research

Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank
Conclusions Individuals hospitalised with COVID-19 have increased risk of incident cardiovascular events across a range of disease and mortality outcomes. The risk of most events is highest in the early postinfection period. Individuals not requiring hospitalisation have increased risk of VTE, but not of other cardiovascular-specific outcomes.
Source: Heart - December 22, 2022 Category: Cardiology Authors: Raisi-Estabragh, Z., Cooper, J., Salih, A., Raman, B., Lee, A. M., Neubauer, S., Harvey, N. C., Petersen, S. E. Tags: Open access, Editor's choice, Press releases, COVID-19 Cardiac risk factors and prevention Source Type: research

Transcatheter versus surgical closure of atrial septal defect in adult patients with tricuspid regurgitation
Conclusions While TAP was effective for the treatment of significant TR, transcatheter ASD closure also significantly reduced TR as well. Transcatheter ASD closure may be considered an alternative treatment option in patients with moderate or severe TR.
Source: Heart - November 24, 2022 Category: Cardiology Authors: Kim, M., Lee, P. H., Kim, D.-H., Jung, S.-H., Lee, S.-A., Lee, S., Kang, D.-H., Song, J.-K., Song, J.-M. Tags: Congenital heart disease Source Type: research

Contemporary demographics, diagnostics and outcomes in non-bacterial thrombotic endocarditis
Conclusions NBTE was more prevalent in females and embolic complications were the most frequent clinical finding. Overall, patients with NBTE had a poor prognosis, particularly in those with lung cancer or metastatic tumours. Further studies in patients with NBTE are needed given its morbidity and mortality.
Source: Heart - September 26, 2022 Category: Cardiology Authors: Quintero-Martinez, J. A., Hindy, J.-R., El Zein, S., Michelena, H. I., Nkomo, V. T., DeSimone, D. C., Baddour, L. M. Tags: Valvular heart disease, Editor's choice Source Type: research

Inter-racial differences in patients undergoing transcatheter aortic valve implantation
Conclusions There were significant differences in baseline and procedural factors among Asian and non-Asian patients who underwent TAVI. Observed inter-racial differences in clinical outcomes were largely explained by baseline differences in clinical, anatomical and procedural factors. Trial registration number NCT03826264 (https://wwwclinicaltrialsgov).
Source: Heart - September 12, 2022 Category: Cardiology Authors: Kang, D.-Y., Ahn, J.-M., Kim, J. B., Yeung, A., Nishi, T., Fearon, W., Cantey, E. P., Flaherty, J. D., Davidson, C. J., Malaisrie, S. C., Park, S. Y., Yun, S.-C., Ko, E., Park, H., Lee, S.-A., Kim, D.-H., Kim, H. J., Kim, J. B., Choo, S. J., Park, D.-W., Tags: Valvular heart disease Source Type: research

Heartbeat: cardiovascular maternal health and disparities in clinical outcomes
Cardiovascular disease continues to account for a high proportion of pregnancy-related deaths in women in the USA. In addition to pre-existing heart disease, gestational hypertension and diabetes, as well as pre-eclampsia and eclampsia, are associated with an increased risk of adverse cardiovascular outcomes both in the short and long-term. In this issue of Heart, Marschner and colleagues1 report an incidence of cardiometabolic conditions (hypertensive disease and diabetes) of 224.3 (95% CI 221.3 to 227.3) per 1000 births among 74 510 women, mean age 26.4 years (SD 5.5) in a cross-sectional study of Medicare patients from ...
Source: Heart - September 12, 2022 Category: Cardiology Authors: Otto, C. M. Tags: Highlights from this issue Source Type: research

Atrial fibrillation following transcatheter atrial septal defect closure: a systematic review and meta-analysis
Conclusions The incidence of new-onset AFi/AFl is relatively low following transcatheter closure of secundum ASDs. The rate of de novo AFi/AFl, however, was significantly higher in elderly patients. Shorter follow-up time was associated with a higher reported incidence of AFi/AFl.
Source: Heart - July 13, 2022 Category: Cardiology Authors: Himelfarb, J. D., Shulman, H., Olesovsky, C. J., Rumman, R. K., Oliva, L., Friedland, J., Farrell, A., Huszti, E., Horlick, E., Abrahamyan, L. Tags: Congenital heart disease Source Type: research