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Interventional Cryoablation Therapy of Paroxysmal Atrial Fibrillation in Young Patients With Low CHADS2 Score: Worth the Risk of Periprocedural and Long-Term Adverse Events?
In this study the long-term effectiveness in the cryoablation group was reported as 69.9% after 12 months, with a mean fluoroscopy exposure time of 63 min. Regarding the adverse events during follow-up, only 1 adverse event (1.2%) occurred in the drug therapy arm (transfusion because of hemorrhage) compared with 32 adverse events (14.2%) in the cryoablation group, not regarding the 24 patients who suffered temporary phrenic nerve palsy. Five strokes, 4 transient ischemic attacks, 2 cases of tamponades, 2 myocardial infarctions, 3 transfusions, 2 atriovenous fistulas, 2 pseudoaneurysms, 4 cases of persistent phrenic nerve...
Source: Journal of the American College of Cardiology - July 26, 2013 Category: Cardiology Authors: Silke D. Braun Tags: Letters to the Editor Source Type: research

Randomized Trial of Complete Versus Lesion-Only Revascularization in Patients Undergoing Primary Percutaneous Coronary Intervention for STEMI and Multivessel Disease The CvLPRIT Trial
ConclusionsIn patients presenting for P-PCI with multivessel disease, index admission complete revascularization significantly lowered the rate of the composite primary endpoint at 12 months compared with treating only the IRA. In such patients, inpatient total revascularization may be considered, but larger clinical trials are required to confirm this result and specifically address whether this strategy is associated with improved survival. (Complete Versus Lesion-only Primary PCI Pilot Study [CvLPRIT]; ISRCTN70913605)
Source: Journal of the American College of Cardiology - March 9, 2015 Category: Cardiology Source Type: research

Fontan Anticoagulation A Never-Ending Debate? ∗
Thrombus formation is a significant cause of morbidity and mortality after Fontan operations. Intracardiac thrombus formation can lead to chronic pulmonary embolism (e.g., from system veins or subpulmonary ventricle) or stroke (e.g., from pulmonary veins or the systemic ventricle). Those “right-sided” embolisms may result in a ventilation/perfusion mismatch or an elevation of pulmonary vascular resistance, both of which may seriously hamper the cavopulmonary circulation. Preventing thromboembolism after the Fontan procedure and the role of a proper prophylaxis remains an ongoing discussion. The published reports are fr...
Source: Journal of the American College of Cardiology - September 13, 2016 Category: Cardiology Source Type: research