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'Exercise pill' could potentially help people with heart failure
Conclusion The protein hCT1 caused heart muscles to grow in a more healthy way in rodents with heart failure. When treatment stopped, the heart went back to its original condition – something that does not happen when the heart grows in a dysfunctional way. There is currently no cure for heart failure and treatment is only available for keeping symptoms under control. Therefore, this very promising early-stage research with potential for developing a drug for people with heart failure, has huge implications. However, it is important to remember that as this is experimental laboratory research, there are many more stage...
Source: NHS News Feed - August 9, 2017 Category: Consumer Health News Tags: Heart/lungs Source Type: news

Can HRT in early menopause cut heart disease risk?
ConclusionThis double-blind RCT found that women taking HRT less than six years after the menopause had slower artery wall thickening than those taking a placebo. This represented the main measure of atherosclerosis progression tested; other measures showed no difference, so the results were not as conclusive as they could have been. Women taking HRT 10 or more years after menopause also showed no difference in atherosclerosis progression compared with a placebo, further complicating the picture.An important limitation of this study is the lack of a patient relevant endpoint, such as cardiovascular events or mortality. Pre...
Source: NHS News Feed - April 1, 2016 Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news

Deep-fried Mars bars – unhealthy, but no killer
Conclusion This study found no significant differences in cerebrovascular reactivity (the body’s ability to respond to breath holding by increasing blood flow to the brain) after eating either a deep-fried Mars bar or porridge. When the researchers analysed men and women separately, they found no significant differences in cerebrovascular reactivity after eating a deep-fried Mars bar or porridge. However, when the researchers compared men with women, they found a significant difference, although whether there is any clinical significance to this finding is unclear. The researchers point out that there are limitations to ...
Source: NHS News Feed - September 30, 2014 Category: Consumer Health News Tags: Food/diet Neurology Obesity Source Type: news

Deep-fried Mars bars: unhealthy, but no killer
Conclusion This study found no significant differences in cerebrovascular reactivity (the body’s ability to respond to breath holding by increasing blood flow to the brain) after eating either a deep-fried Mars bar or porridge. When the researchers analysed men and women separately, they found no significant differences in cerebrovascular reactivity after eating a deep-fried Mars bar or porridge. However, when the researchers compared men with women, they found a significant difference, although whether there is any clinical significance to this finding is unclear. The researchers point out that there are limitations to ...
Source: NHS News Feed - September 30, 2014 Category: Consumer Health News Tags: Food/diet Neurology Obesity Source Type: news

Parental smoking 'ages' children’s arteries
ConclusionOverall, this secondary analysis study provides preliminary evidence of the effects of parental passive smoking on the artery walls of children and adolescents in adulthood. The researchers attempted to adjust for potential factors that could influence risk (confounders), such as: age sex height weight smoking status physical activity levels alcohol consumption schooling level of the parent(s)In their analysis, they also took into consideration cardiovascular risk factors of the participants in adulthood. There are some limitations to the study, which are worth noting. Parental smoking status was self-re...
Source: NHS News Feed - March 5, 2014 Category: Consumer Health News Tags: Heart/lungs Pregnancy/child Source Type: news

Scan could detect those on brink of heart attack
Conclusion This is a valuable study which shows the promise of using PET-CT with radioactively labelled sodium fluoride (NaF) as a way of identifying fatty deposits in the heart arteries that could be at risk of rupturing and causing a heart attack. The results confirmed that the marker used in this study (NaF) was better than the chemical marker normally used in PET-CT scans (FDG). The technique has the principal value of being a non-invasive technique compared with coronary angiography, which is the standard method used to look at blockages in heart arteries. As it does not involve surgical intervention, this could ha...
Source: NHS News Feed - November 11, 2013 Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news