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Two older drugs could be 'repurposed' to fight dementia
Conclusion This early stage experimental research has demonstrated a beneficial neurological effect of trazodone and dibenzoylmethane on mice with diseases mimicking neurodegenerative diseases. It is important to acknowledge that this is animal research and therefore the drugs might not have the same effect when they are trialled on humans. That being said, trazodone is already an approved drug for depression and sleep problems and has therefore already passed safety tests. If the mechanisms of neurodegeneration in humans and mice are similar, it is possible trazodone could be used in the future in treating Alzheimer's and...
Source: NHS News Feed - April 20, 2017 Category: Consumer Health News Tags: Older people Neurology Medication Source Type: news

Neural correlates of action recognition and object knowledge in neurodegenerative disease (P6.196)
CONCLUSIONS: Our results suggest that action recognition is supported by a distributed left lateralized functional network that exhibits dissociable roles. In particular, left mid-posterior temporal and inferior parietal areas seem critical for representation of the gestural component of action recognition while frontal inferior regions may support cognitive control requirements common to all 3 tests.Disclosure: Dr. santos has nothing to disclose. Dr. Illan-Gala has nothing to disclose. Dr. Vinceti has nothing to disclose. Dr. Mandelli has nothing to disclose. Dr. Hubbard has nothing to disclose. Dr. Miller has nothing to ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Santos, M., Illan-Gala, I., Vinceti, G., Mandelli, M. L., Hubbard, H., Miller, Z., Rabinovici, G., Miller, B., Gorno Tempini, M. Tags: Aging, Dementia, Cognitive, and Behavioral Neurology: Neuropsychiatry and Behavioral Neurology Source Type: research

Dementia rates dropping
Conclusion This study suggests that the prevalence of dementia in over 65s in 2011 is lower than would have been expected.  The study had many strengths, including the large number of people it interviewed from different areas and the consistent research methods adopted in 1991 and again in 2011, particularly using the same criteria to diagnose dementia at both time points. This means we can be relatively sure that its conclusions are reliable. That said, it does have some limitations to consider. The response rate in 2011 (56%) was much lower than in 1991 (80%). The study authors offer a number of explanations for this...
Source: NHS News Feed - July 17, 2013 Category: Consumer Health News Tags: Neurology Older people Medical practice Source Type: news