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Early Magnetic Resonance Imaging and Cognitive Markers of Hereditary Cerebral Amyloid Angiopathy Brief Report
Background and Purpose—Early markers for cerebral amyloid angiopathy are largely unknown. We aimed to identify which magnetic resonance imaging (MRI) (performed at 7 and 3T) and cognitive markers are an early sign in (pre) symptomatic subjects with hereditary cerebral hemorrhage with amyloidosis-Dutch type.Methods—Twenty-seven DNA-proven Dutch-type mutation carriers (15 symptomatic and 12 presymptomatic) (mean age of 45.9 years) and 33 controls (mean age of 45.6 years) were included. 7T and 3T MRI was performed, cerebral amyloid angiopathy and small-vessel disease type MRI markers were estimated, and cognitive performa...
Source: Stroke - November 27, 2016 Category: Neurology Authors: Sanneke van Rooden, Anna M. van Opstal, Gerda Labadie, Gisela M. Terwindt, Marieke J.H. Wermer, Andrew G. Webb, Huub A.M. Middelkoop, Steven M. Greenberg, Jeroen van der Grond, Mark A. van Buchem Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Cognitive Impairment Brief Reports Source Type: research

Socioeconomic Status and the Quality of Acute Stroke Care Clinical Sciences
We examined data from the China National Stroke Registry recording consecutive stroke patients between September 2007 and August 2008. Baseline low SES was measured using educational level
Source: Stroke - October 23, 2016 Category: Neurology Authors: Pan, Y., Chen, R., Li, Z., Li, H., Zhao, X., Liu, L., Wang, C., Wang, Y., Tags: Quality and Outcomes, Ischemic Stroke Original Contributions Source Type: research

Substantial Progress Yet Significant Opportunity for Improvement in Stroke Care in China Clinical Sciences
Conclusions—Adherence to stroke performance metrics has increased over time, but significant opportunities remain for further improvement. Continuous stroke quality improvement program should be developed as a national priority in China.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Li, Z., Wang, C., Zhao, X., Liu, L., , Li, H., Shen, H., Liang, L., Bettger, J., Yang, Q., Wang, D., Wang, A., Pan, Y., Jiang, Y., Yang, X., Zhang, C., Fonarow, G. C., Schwamm, L. H., Hu, B., Peterson, E. D., Xian, Y., Wang, Y., Tags: Clinical Studies, Health Services, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Parental Care-Seeking Behavior and Prehospital Timelines of Care in Childhood Arterial Ischemic Stroke Brief Reports
Conclusions— Stroke recognition and care-seeking behavior are suboptimal, with less than half the parents considering stroke or calling an ambulance. Initiatives are required to educate parents about appropriate actions to facilitate time-critical interventions.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Mackay, M. T., Stojanovski, B., Mosley, I., Churilov, L., Donnan, G. A., Monagle, P. Tags: Pediatrics, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Strictly Lobar Cerebral Microbleeds Are Associated With Cognitive Impairment Clinical Sciences
Conclusions— Strictly lobar, but not deep or infratentorial, CMBs are associated with changes in cognitive function, especially in visuospatial executive functions. Cerebral amyloid angiopathy may be the underlying pathology associated with CMB-related cognitive impairment.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Chung, C.-P., Chou, K.-H., Chen, W.-T., Liu, L.-K., Lee, W.-J., Chen, L.-K., Lin, C.-P., Wang, P.-N. Tags: Aging, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Cognitive Impairment Clinical Sciences Source Type: research

Remote Lower White Matter Integrity Increases the Risk of Long-Term Cognitive Impairment After Ischemic Stroke in Young Adults Clinical Sciences
Conclusions— These findings indicate that although stroke has an acute onset, it might have long lasting effects on remote white matter integrity and thereby increases the risk of long-term cognitive impairment.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Schaapsmeerders, P., Tuladhar, A. M., Arntz, R. M., Franssen, S., Maaijwee, N. A. M., Rutten-Jacobs, L. C. A., Schoonderwaldt, H. C., Dorresteijn, L. D. A., van Dijk, E. J., Kessels, R. P. C., de Leeuw, F.-E. Tags: Magnetic Resonance Imaging (MRI), Cognitive Impairment, Ischemic Stroke Clinical Sciences Source Type: research

Incidence of Transient Ischemic Attack in Auckland, New Zealand, in 2011 to 2012 Clinical Sciences
Conclusions— This study describes the burden of TIA in an era of aggressive primary and secondary vascular risk factor management. Education programs for medical practitioners and patients around the identification and management of atrial fibrillation are required.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Barber, P. A., Krishnamurthi, R., Parag, V., Anderson, N. E., Ranta, A., Kilfoyle, D., Wong, E., Green, G., Arroll, B., Bennett, D. A., Witt, E., Rush, E., Minsun Suh, F., Theadom, A., Rathnasabapathy, Y., Te Ao, B., Parmar, P., Feigin, V. L., for the ARC Tags: Epidemiology, Race and Ethnicity, Risk Factors, Cerebrovascular Disease/Stroke, Transient Ischemic Attack (TIA) Clinical Sciences Source Type: research

Association of Major Depressive Episodes With Stroke Risk in a Prospective Study of 0.5 Million Chinese Adults Clinical Sciences
Conclusions— Findings from this large prospective study suggest that the presence of MDE is a risk factor for stroke, especially in smokers.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Sun, J., Ma, H., Yu, C., Lv, J., Guo, Y., Bian, Z., Yang, L., Chen, Y., Shen, H., Chen, Z., Hu, Z., Li, L., on behalf of the China Kadoorie Biobank Collaborative Group Tags: Mental Health, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Current Status and Time Trends of Oral Anticoagulation Use Among Chinese Patients With Nonvalvular Atrial Fibrillation: The Chinese Atrial Fibrillation Registry Study Clinical Sciences
Conclusions— An improvement of OAC use among Chinese patients with AF in Beijing is observed in recent years although only 36.5% of patients with CHA2DS2-VASc score ≥2 received OAC. However, variations between different hospitals were large, suggesting that better education and awareness are needed to improve efforts for stroke prevention among AF patients. Clinical Trial Registration— URL: http://www.chictr.org.cn/showproj.aspx?proj=5831. Unique identifier: ChiCTR-OCH-13003729.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Chang, S.-S., Dong, J.-Z., Ma, C.-S., Du, X., Wu, J.-H., Tang, R.-B., Xia, S.-J., Guo, X.-Y., Yu, R.-H., Long, D.-Y., Bai, R., Liu, N., Sang, C.-H., Jiang, C.-X., Liu, X.-H., Pan, J.-H., Lip, G. Y. H. Tags: Atrial Fibrillation, Epidemiology, Anticoagulants Clinical Sciences Source Type: research

Reassessing the Stroke Belt: Using Small Area Spatial Statistics to Identify Clusters of High Stroke Mortality in the United States Brief Reports
Conclusions— Clusters of high stroke mortality exist beyond the 8-state stroke belt, and variation exists within the stroke belt. Reconsideration of the stroke belt definition and increased attention to local determinants of health underlying small area regional variability could inform targeted healthcare interventions.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Karp, D. N., Wolff, C. S., Wiebe, D. J., Branas, C. C., Carr, B. G., Mullen, M. T. Tags: Epidemiology, Risk Factors, Mortality/Survival, Quality and Outcomes, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Shape of the Central Sulcus and Disability After Subcortical Stroke: A Motor Reserve Hypothesis Clinical Sciences
Conclusions— The severity of disability in patients with a positive history of small subcortical ischemic stroke caused by a severe cerebral small vessel disease is related to the shape of the central sulcus, independently of the main determinants of disability. These results support the concept of a motor reserve that could modulate the clinical severity in patients with a positive history of small subcortical ischemic stroke.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Jouvent, E., Sun, Z. Y., De Guio, F., Duchesnay, E., Duering, M., Ropele, S., Dichgans, M., Mangin, J.-F., Chabriat, H. Tags: Magnetic Resonance Imaging (MRI), CADASIL, Ischemic Stroke Clinical Sciences Source Type: research

Validating a Pragmatic Approach to Cognitive Screening in Stroke Prevention Clinics Using the Montreal Cognitive Assessment Clinical Sciences
Conclusions— Stratifying participants into 3 categories facilitates the identification of a homogenous group at low risk for CI, as well as 2 other groups with intermediate and higher risk. This approach could facilitate clinical care pathways and patient selection for research.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Swartz, R. H., Cayley, M. L., Lanctot, K. L., Murray, B. J., Smith, E. E., Sahlas, D. J., Herrmann, N., Cohen, A., Thorpe, K. E. Tags: Epidemiology, Secondary Prevention, Cerebrovascular Disease/Stroke, Cognitive Impairment Clinical Sciences Source Type: research

Determinants of Emergency Medical Services Utilization Among Acute Ischemic Stroke Patients in Hubei Province in China Brief Reports
Conclusions— A very low proportion of patients with acute ischemic stroke used the EMS in Hubei province in China. Considerable education programs are required regarding knowledge of potential symptoms and the importance of EMS for stroke.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Yin, X., Yang, T., Gong, Y., Zhou, Y., Li, W., Song, X., Wang, M., Hu, B., Lu, Z. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Progression of White Matter Disease and Cortical Thinning Are Not Related in Older Community-Dwelling Subjects Clinical Sciences
Conclusions— Our results show that WMH volume and cortical thinning both worsen with age and are associated cross-sectionally within and surrounding the Sylvian fissure. However, changes in WMH volume and cortical thinning from 73 to 76 years are not associated longitudinally in these relatively healthy older subjects. The underlying cause(s) of WMH growth and cortical thinning have yet to be fully determined.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Dickie, D. A., Karama, S., Ritchie, S. J., Cox, S. R., Sakka, E., Royle, N. A., Aribisala, B. S., Hernandez, M. V., Maniega, S. M., Pattie, A., Corley, J., Starr, J. M., Bastin, M. E., Evans, A. C., Deary, I. J., Wardlaw, J. M. Tags: Risk Factors, Computerized Tomography (CT), Magnetic Resonance Imaging (MRI) Clinical Sciences Source Type: research

Montreal Cognitive Assessment: One Cutoff Never Fits All Brief Reports
Conclusions— Conventional single cutoff scores are associated with substantially high rates of misclassification especially in older and less-educated patients with stroke. These results caution against the use of one-size-fits-all cutoffs on the MoCA.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Wong, A., Law, L. S. N., Liu, W., Wang, Z., Lo, E. S. K., Lau, A., Wong, L. K. S., Mok, V. C. T. Tags: Rehabilitation, Cognitive Impairment Brief Reports Source Type: research

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