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Source: Folia Neuropathologica
Drug: Insulin
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Total 121 results found since Jan 2013.
MiR-125a-5p silencing inhibits cerebral ischemia-induced injury through targeting IGFBP3
This study conducted a series of experiments that were designed to elucidate the regulatory action of miR-125a-5p in ischemic brain injury and its underlying mechanisms. The results of this study found that the expression of miR-125a-5p was increased in BV2 microglial cells under oxygen-glucose deprivation/reoxygenation (OGD/R) setting, as well as in rat brain tissue after middle cerebral artery occlusion (MCAO). OGD/R triggered BV2 microglial cell apoptosis, whereas downregulation of miRNA-125a-5p suppressed the apoptosis rate in OGD/R-induced BV2 microglial cells. Subsequently, insulin-like growth factor binding protein ...
Source: Folia Neuropathologica - July 21, 2021 Category: Neurology Authors: Bo Song Jing Xu Ping Zhong Lei Fang Source Type: research
