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Long-term Dosing of Intrathecal Baclofen in the Treatment of Spasticity after Acquired Brain Injury
Conclusion Despite the long-term use of ITB therapy in this cohort, the mean daily dose of intrathecal baclofen continued to require adjustments. There was no significant difference in the mean daily dose between patients with a diagnosis of TBI, stroke, or HIE. A complex dosing pattern was used more frequently in patients with stroke.
Source: PMandR - January 7, 2017 Category: Rehabilitation Source Type: research

Intrathecal Versus Oral Baclofen: A Matched Cohort Study of Spasticity, Pain, Sleep, Fatigue, and Quality of Life
Conclusions Long-term treatment with intrathecal compared with oral baclofen is associated with reduced spasm frequency and severity as well as greater dose stability. These benefits must be weighed against the risks of internal pump and catheter placement in patients considering intrathecal baclofen therapy.
Source: PMandR - November 22, 2015 Category: Rehabilitation Source Type: research

Intrathecal versus Oral Baclofen; a Matched Cohort Study of Spasticity, Pain, Sleep, Fatigue and Quality of Life
Conclusions Long-term treatment with intrathecal compared to oral baclofen is associated with reduced spasm frequency and severity as well as greater dose stability. These benefits must be weighted against the risks of internal pump and catheter placement in patients considering intrathecal baclofen therapy.
Source: PMandR - October 21, 2015 Category: Rehabilitation Source Type: research