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Specialty: Cardiology
Drug: Phenytoin
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Total 1 results found since Jan 2013.
Anti-Epileptic Drug Target Perturbation and Intracranial Aneurysm Risk: Mendelian Randomization and Colocalization Study
CONCLUSIONS: CNNM2 is a driver of the pleiotropy between IA and anti-epileptic drug targets. Administration of the anti-epileptic drugs phenytoin, valproic acid, or carbamazepine may be expected to decrease CNNM2 levels and therefore subsequently decrease IA risk. CNNM2 is therefore an important target to investigate further for its role in the pathogenesis of IA.PMID:36300369 | DOI:10.1161/STROKEAHA.122.040598
Source: Atherosclerosis - October 27, 2022 Category: Cardiology Authors: Mark K Bakker Tijmen van Straten Michael Chong Guillaume Par é Dipender Gill Ynte M Ruigrok Source Type: research
