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Amoxicillin/clavulanic acid-associated severe neutropenia
A 72-year-old man presented with an abnormal blood count and was admitted. His history included hypertension and hyperlipidaemia with an old myocardial infarction and mild stroke; liver cirrhosis due to non-alcoholic steatohepatitis (NASH) with hypersplenism and oesophageal varices but no ascites, oedema or bleeding; and benign prostatic hypertrophy. His medications (unchanged for years) included furosemide, spironolactone, bisoprolol, rosuvastatin, alfuzosin and omeprazole. Two weeks prior, he was discharged from our department after left leg cellulitis and Streptococcus pyogenes bacteraemia responsive to parenteral clind...
Source: Postgraduate Medical Journal - March 22, 2022 Category: General Medicine Authors: Schattner, A., Dubin, I. Tags: Adverse drug reactions Source Type: research

Preventing diarrhoea in enteral nutrition: the impact of the delivery set hang time
ConclusionsThe 24 h DSHT was independently associated with a lower risk of diarrhoea and longer diarrhoea‐free survival in hospitalised patients with acute stroke under ETF, compared with a 72/96 h DSHT.
Source: International Journal of Clinical Practice - May 4, 2015 Category: Internal Medicine Authors: J. J. Arevalo‐Manso, P. Martinez‐Sanchez, B. Juarez‐Martin, B. Fuentes, G. Ruiz‐Ares, B. E. Sanz‐Cuesta, P. Parrilla‐Novo, E. Diez‐Tejedor Tags: Original Paper Source Type: research

Have antibiotic changes upped heart infections?
Conclusion This is valuable and timely research, which has looked at trends before and after NICE's 2008 guidance on the prevention of infective endocarditis in people undergoing invasive procedures. This examined: changes in the prescription of antibiotics for the prevention of infective endocarditis changes in the number of cases of infective endocarditis diagnosed NICE's recommendation was based on an examination of the evidence of the effectiveness of antibiotics in preventing infective endocarditis, weighing the benefits and health outcomes (such as reduction in illness and deaths), risks and costs.   The ...
Source: NHS News Feed - November 19, 2014 Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news