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Drug: Methylprednisolone

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Acute kidney injury and undiagnosed immunoglobulin A nephropathy after dabigatran therapy.
We report a case of a man who resumed dabigatran after 6 weeks of prior therapy and began experiencing hematuria with worsening kidney function. Renal biopsy with immunofluorescence and electron microscopy showed mesangial deposits consistent with immunoglobulin A nephropathy. With discontinuation of dabigatran and addition of methylprednisolone, the gross hematuria cleared and urine output improved. PMID: 29904298 [PubMed]
Source: Baylor University Medical Center Proceedings - June 16, 2018 Category: Universities & Medical Training Authors: Jansky L, Mukkamala P, Jebakumar D, Rao A, Goldson TM, Forjuoh SN Tags: Proc (Bayl Univ Med Cent) Source Type: research