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Source: Cryobiology
Drug: Inderal

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Total 1 results found since Jan 2013.

Negative inotropic effects of epinephrine in the presence of increased β-adrenoceptor sensitivity during hypothermia in a rat model.
CONCLUSIONS: This experiment shows a hypothermia-induced in vivo and in vitro increase of cardiac β-adrenoceptor sensitivity, and simultaneous lack of inotropic effects of Epi in the presence of increased TPR. Our findings therefore indicate that hypothermia-induced reduction in inotropic effects of Epi is due to substantial elevation of TPR, rather than β-adrenoceptor dysfunction. PMID: 25445571 [PubMed - as supplied by publisher]
Source: Cryobiology - November 13, 2014 Category: Biology Authors: Dietrichs ES, Schanche T, Kondratiev T, Gaustad SE, Sager G, Tveita T Tags: Cryobiology Source Type: research