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Hypersomnia and Reduction in Essential Tremor after Bilateral Subthalamic Ischemic Stroke (P4.285)
Conclusions:Prevalence of hypersomnia among stroke patients ranges from 1.1 to 27[percnt].A reduction in the activity of arousal systems underlies most forms of post stroke hypersomnia.Multiple changes like reduction in the amount of NREM sleep, sleep time, sleep spindles, REM sleep ( in occipital strokes ) were also described depending on the location of the stroke. Thalamic and brainstem strokes can present with pathological EEG patterns like alpha coma.Along with bilateral thalamic strokes, strokes in thalamo-mesencephalic regions, upper pons and medial pontomedullary lesions can cause marked hypersomnia. Cortical and s...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Pesala, S., Nalleballe, K., Bollu, P. Tags: Parasomnias and Hypersomnias Source Type: research

Low-dose propranolol and exercise capacity in postural tachycardia syndrome: A randomized study
Conclusions: These findings suggest that nonselective β-blockade with propranolol, when used at the low doses frequently used for treatment of POTS, may provide a modest beneficial effect to improve heart rate control and exercise capacity. Classification of evidence: This study provides Class II evidence that a single low dose of propranolol (20 mg) as compared with placebo is useful in increasing maximum exercise capacity measured 1 hour after medication.
Source: Neurology - May 20, 2013 Category: Neurology Authors: Arnold, A. C., Okamoto, L. E., Diedrich, A., Paranjape, S. Y., Raj, S. R., Biaggioni, I., Gamboa, A. Tags: Autonomic diseases, Cardiac, Class II ARTICLE Source Type: research