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Condition: Thrombosis
Drug: Pradaxa

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Total 508 results found since Jan 2013.

Prothrombin complex concentrate in the management of major bleeding induced by oral anticoagulant therapy
CONCLUSION: Prothrombin complex concentrate can effectively reverse the effects of warfarin and rivaroxaban in patients with major bleeding, but only partially reverses the effect of dabigatran.PMID:35110348 | DOI:10.15537/smj.2022.43.2.20210736
Source: Saudi Medical Journal - February 3, 2022 Category: Middle East Health Authors: Mohammed AlSheef Ghaydaa Kullab Modhi Alajmi Ruba Aldhaheri Sultan Al Baqmi Haya Alajlan Abdul Rehman Z Zaidi Amani Abu-Shaheen Source Type: research

Dabigatran in cardiovascular disease management: A comprehensive review
This article provides a comprehensive review on the role of dabigatran in various cardiovascular diseases.PMID:35070113 | PMC:PMC8716972 | DOI:10.4330/wjc.v13.i12.710
Source: World Journal of Cardiology - January 24, 2022 Category: Cardiology Authors: Ayesha Javed Muhammad Ajmal Aaron Wolfson Source Type: research

Thrombin in complex with dabigatran can still interact with PAR-1 via exosite-I and instigate loss of vascular integrity
CONCLUSIONS: Proteolytically inactive thrombin in complex with dabigatran evokes loss of barrier function that can be prevented by a PAR-1 mimicking peptide blocking thrombin's exosite-I.PMID:35037739 | DOI:10.1111/jth.15642
Source: Thrombosis and Haemostasis - January 17, 2022 Category: Hematology Authors: Sophie C D ólleman Stijn M Agten Henri M H Spronk Tilman M Hackeng Mettine H A Bos Henri H Versteeg Anton Jan van Zonneveld Hetty C de Boer Source Type: research