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Clinical impact of beta-blockers at discharge on long-term clinical outcomes in patients with non-reduced ejection fraction after acute myocardial infarction
CONCLUSIONS: The J-MINUET study revealed the clinical benefit of beta-blockers in AMI patients with non-REF after primary PCI.PMID:35995686 | DOI:10.1016/j.jjcc.2022.08.002
Source: Journal of Cardiology - August 22, 2022 Category: Cardiology Authors: Azusa Sakagami Tsunenari Soeda Yoshihiko Saito Koichi Nakao Yukio Ozaki Kazuo Kimura Junya Ako Teruo Noguchi Satoru Suwa Kazuteru Fujimoto Kazuoki Dai Takashi Morita Wataru Shimizu Atsushi Hirohata Yasuhiro Morita Teruo Inoue Atsunori Okamura Toshiaki Man Source Type: research

Trends in optimal medical therapy at discharge and clinical outcomes in patients with acute coronary syndrome in Thailand.
CONCLUSIONS: The five-drugs comprising OMT were associated with a reduction in all-cause mortality and MACE in patients with ACS. Nevertheless, OMT prescribing remains underused and could be enhanced in the real-world setting. PMID: 33455848 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - January 14, 2021 Category: Cardiology Authors: Wongsalap Y, Kengkla K, Poolpun D, Saokaew S Tags: J Cardiol Source Type: research

Total management of chronic obstructive pulmonary disease (COPD) as an independent risk factor for cardiovascular disease.
Abstract Patients with cardiovascular disease (CVD) often have multiple comorbid conditions that may interact with each other, confound the choice of treatments, and reduce mortality. Chronic obstructive pulmonary disease (COPD) is one of the most important comorbidities of CVD, which causes serious consequences in patients with ischemic heart disease, stroke, arrhythmia, and heart failure. COPD shares common risk factors such as tobacco smoking and aging with CVD, is associated with less physical activity, and produces systemic inflammation and oxidative stress. Overall, patients with COPD have a 2-3-fold increas...
Source: Journal of Cardiology - March 18, 2017 Category: Cardiology Authors: Onishi K Tags: J Cardiol Source Type: research

Heart failure: What does ejection fraction have to do with it?
Abstract Heart failure (HF) occurs across the entire range of left ventricular (LV) ejection fractions (EF), not just reduced EF. Nearly half or more patients presenting with HF have a preserved EF>0.50 (HFpEF). Diastolic dysfunction is apparent in all patients with HF, regardless of EF. A preserved EF indicates that the end-diastolic volume is appropriate for the stroke volume, and a reduced EF indicates that the end-diastolic volume is enlarged relative to stroke volume (i.e. the LV is dilated). Most therapies proven to be effective in HF with a reduced EF (ACE-inhibitors, angiotensin receptor blockers, beta-...
Source: Journal of Cardiology - May 11, 2013 Category: Cardiology Authors: Iwano H, Little WC Tags: J Cardiol Source Type: research