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E-190 Trends in admissions for intracranial dissections in the United States
ConclusionThe prevalence of uIADs among hospitalized patients is scarce, and only 2% of craniocervical dissection-related AIS is due to uIAD. Compared to IAs, patients were more likely younger and male, and uIAD more commonly led to acute ischemic stroke and motor deficits. The trend in age remained stable across the four years analyzed, while the proportion of females increased. There was no trend in the proportion of races among uIADs, however.Disclosures W. Wahood: None. G. Lanzino: None. Z. Keser: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Wahood, W., Lanzino, G., Keser, Z. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Carotid artery revascularization using the Walrus balloon guide catheter: safety and feasibility from a US multicenter experience
Conclusion Walrus BGC for proximal flow control is safe and effective during eCAS and tCAS. Procedural success was achieved in all cases, with favorable safety and functional outcomes on short-term follow-up.
Source: Journal of NeuroInterventional Surgery - June 16, 2022 Category: Neurosurgery Authors: Salem, M. M., Kvint, S., Baig, A. A., Monteiro, A., Cortez, G. M., Kuhn, A. L., Goren, O., Dalal, S., Jankowitz, B. T., Choudhri, O., Raper, D., Tanweer, O., Jabbour, P., Kan, P., Starke, R. M., Levy, E. I., Griessenauer, C. J., Puri, A. S., Hanel, R., Si Tags: New devices New devices and techniques Source Type: research

Mechanical thrombectomy beyond the circle of Willis: efficacy and safety of different techniques for M2 occlusions
Conclusion Stent-retrievers and a combined approach for M2 occlusions seem more effective than direct aspiration, but with higher rates of iSAH. This leads to no detectable difference in clinical outcome at 3 months.
Source: Journal of NeuroInterventional Surgery - May 13, 2022 Category: Neurosurgery Authors: Renieri, L., Valente, I., Dmytriw, A. A., Puri, A. S., Singh, J., Nappini, S., Nencini, P., Kaliaev, A., Abdalkader, M., Alexandre, A., Garignano, G., Vivekanandan, S., Fong, R. P., Parra-Farinas, C., Spears, J., Gomez-Paz, S., Ogilvy, C., Regenhardt, R. Tags: Ischemic stroke Source Type: research

Revascularization of Hemorrhagic Moyamoya Disease in a North American Cohort: The Role of Timing in Perioperative and Long-Term Outcomes
BACKGROUND: Several East Asian studies have examined the role of revascularization in the context of hemorrhagic moyamoya disease (MMD) and found a decrease in postoperative rehemorrhage rates. To date, no data exist comparing revascularization with conservative management in North American patients with hemorrhagic MMD. OBJECTIVE: To compare the clinical outcomes of conservative management vs surgical revascularization for North American patients with hemorrhagic MMD and investigate the effect of revascularization timing. METHODS: We retrospectively studied the mortality and stroke-free survival of patie...
Source: Neurosurgery - March 24, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Cerebrovascular Source Type: research

Rates of adverse events in patients with ischemic stroke treated at thrombectomy capable hospitals
Conclusions A decrease in-hospital adverse events and improved discharge outcomes were observed among patients with ischemic stroke admitted to a TCH compared with a non-TCH.
Source: Journal of NeuroInterventional Surgery - March 18, 2022 Category: Neurosurgery Authors: Chaudhry, S. A., Sadaf, H., Laleka, I., Nasir, W., Witzel, C., Bahiru, Z., Fang, Y., Ishfaq, F., Altaweel, L. R., Qureshi, A. I. Tags: Ischemic stroke Source Type: research

Comparative study of on-label versus off-label treatment of intracranial aneurysms with the Pipeline embolization device
CONCLUSIONS: In real-world practice, off-label use of PED is common and can achieve similar efficacy as on-label use. However, in aggregate, off-label use was found to carry an increased rate of ischemic complications. With judicious attention to safety and individual patient characteristics, these results highlight the scale and general feasibility of off-label PED use by experts.PMID:35090133 | DOI:10.3171/2021.11.JNS212481
Source: Journal of Neurosurgery - January 28, 2022 Category: Neurosurgery Authors: Samuel J Cler David C Lauzier Arindam R Chatterjee Joshua W Osbun Christopher J Moran Akash P Kansagra Source Type: research

Periprocedural safety of saccular aneurysm embolization with the Penumbra SMART Coil System: a SMART registry subset analysis
Conclusion The low rates of thromboembolic complications and RRP events demonstrate the adequate safety profile of the SMART Coil System to treat cerebral aneurysms in routine clinical practice. Trial registration number NCT02729740.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Starke, R. M., Park, M. S., Bellon, R., Bohnstedt, B., Schirmer, C. M., De Leacy, R., Fiorella, D., Yoo, A. J., Spiotta, A. M., On behalf of the SMART Registry Investigators Tags: Open access, Hemorrhagic stroke Source Type: research

Health economic impact of first-pass success among patients with acute ischemic stroke treated with mechanical thrombectomy: a United States and European perspective
Conclusions FPE resulted in improved clinical outcomes, translating into lower healthcare resource use and lower estimated costs.
Source: Journal of NeuroInterventional Surgery - November 18, 2021 Category: Neurosurgery Authors: Zaidat, O. O., Ribo, M., Mattle, H. P., Saver, J. L., Bozorgchami, H., Yoo, A. J., Ehm, A., Kottenmeier, E., Cameron, H. L., Qadeer, R. A., Andersson, T. Tags: Open access, Ischemic stroke Source Type: research

Duration of symptomatic stroke and successful reperfusion with endovascular thrombectomy for anterior circulation large vessel occlusive stroke
Conclusion In a real-world cohort of acute ischemic stroke patients with anterior circulation occlusion treated with endovascular therapy, longer duration of symptomatic stroke is associated with lower rates of successful reperfusion and reperfusion on the first pass.
Source: Journal of NeuroInterventional Surgery - November 18, 2021 Category: Neurosurgery Authors: de Havenon, A., Alexander, M. D., Nogueira, R. G., Haussen, D. C., Castonguay, A. C., Linfante, I., Johnson, M. A., Nguyen, T. N., Mokin, M., Zaidat, O. O. Tags: Ischemic stroke Source Type: research

Correlation between intracranial vertebral artery stenosis diameter measured by digital subtraction angiography and cross-sectional area measured by optical coherence tomography
Conclusion Measurement of the narrowest diameter was not a reliable predictor of the cross-sectional area of V4 stenosis. Larger studies are therefore needed to develop a new evaluation system based on V4 stenosis.
Source: Journal of NeuroInterventional Surgery - October 15, 2021 Category: Neurosurgery Authors: Feng, Y., Wu, T., Wang, T., Li, Y., Li, M., Li, L., Yang, B., Bai, X., Zhang, X., Wang, Y., Gao, P., Chen, Y., Ma, Y., Jiao, L. Tags: Ischemic stroke Source Type: research

COVID-19 meets neurointervention on the pages of JNIS
As 2019 came to a close, a novel B-coronavirus, labeled by the World Health Organization as COVID-19, was noted to be spreading in China.1 The COVID-19 virus is an enveloped single-strand, positive-sense RNA, which means that the virus can use its RNA as the template from which to create proteins needed for propagation and, ultimately, spread. The name coronavirus refers to the characteristic crown-like appearance of these viruses that is seen on electron microscopy. By spring 2020, COVID-19 was spreading rapidly throughout the United States and Europe, and neurointerventionalists soon found themselves on the frontline.2 T...
Source: Journal of NeuroInterventional Surgery - September 15, 2021 Category: Neurosurgery Authors: Milburn, J. M., Regenhardt, R. W., Fiehler, J., Fargen, K. M., Hirsch, J. A. Tags: COVID-19 Commentary Source Type: research

O-005 Comparison of on-label versus off-label treatment of intracranial aneurysms with the pipeline embolization devices
ConclusionIn real-world practice, off-label uses of PED can achieve similar safety and efficacy to on-label uses, though there may be a slightly higher rate of ischemic complications in off-label uses. Expert judgment is a useful supplement to official guidelines when assessing reasonable PED use beyond its approved indications.Disclosures S. Cler: None. D. Lauzier: None. A. Kansagra: 2; C; Penumbra, Microvention, iSchemaView.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Cler, S., Lauzier, D., Kansagra, A. Tags: Oral abstracts Source Type: research

O-010 Racial disparity in mechanical thrombectomy utilization: multicenter registry results from 2016-2020
ConclusionsBlack stroke patients underwent MT less frequently than Whites, likely in part due to longer times from LKW to hospital arrival and a lower rate of documented aLVO. Further studies are needed to assess whether extending the MT time window and more aggressive LVO screening protocols mitigate this disparity.Disclosures A. Wallace: None. D. Gibson: 2; C; iSchemaView, Medtronic, Siemens. K. Asif: None. D. Sahlein: 2; C; Medtronic, Microvention, Stryker, Phenox. 3; C; Medtronic. S. Warach: None. T. Malisch: None. M. Lamonte: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Wallace, A., Gibson, D., Asif, K., Sahlein, D., Warach, S., Malisch, T., Lamonte, M. Tags: Oral abstracts Source Type: research

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