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Periprocedural safety of saccular aneurysm embolization with the Penumbra SMART Coil System: a SMART registry subset analysis
Conclusion The low rates of thromboembolic complications and RRP events demonstrate the adequate safety profile of the SMART Coil System to treat cerebral aneurysms in routine clinical practice. Trial registration number NCT02729740.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Starke, R. M., Park, M. S., Bellon, R., Bohnstedt, B., Schirmer, C. M., De Leacy, R., Fiorella, D., Yoo, A. J., Spiotta, A. M., On behalf of the SMART Registry Investigators Tags: Open access, Hemorrhagic stroke Source Type: research

Carotid artery revascularization using the Walrus balloon guide catheter: safety and feasibility from a US multicenter experience
Conclusion Walrus BGC for proximal flow control is safe and effective during eCAS and tCAS. Procedural success was achieved in all cases, with favorable safety and functional outcomes on short-term follow-up.
Source: Journal of NeuroInterventional Surgery - June 16, 2022 Category: Neurosurgery Authors: Salem, M. M., Kvint, S., Baig, A. A., Monteiro, A., Cortez, G. M., Kuhn, A. L., Goren, O., Dalal, S., Jankowitz, B. T., Choudhri, O., Raper, D., Tanweer, O., Jabbour, P., Kan, P., Starke, R. M., Levy, E. I., Griessenauer, C. J., Puri, A. S., Hanel, R., Si Tags: New devices New devices and techniques Source Type: research

O-052 The pennsylvania post-market multicenter experience with flow re-direction endoluminal device (FRED)
ConclusionThe results of the early post-market experience with the FRED device show reasonable safety and adequate aneurysmal occlusion rates comparable to other flow diverters. However, more extensive multicenter studies with more extended follow-up data are needed to assess the long-term safety and durability of the device.Abstract O-052 Table 1Baseline descriptive statistics Number of patients n=61 Gender Male 11 (18%) Female 50 (82%) Age (Years: median; IQR) 58 (51 – 68) Multiple Intracranial Aneurysms 21 (34.4%) Family history of aneurysms 9 (14.8%) Smoking History Never smokers 26 (42.6%) Past smokers 13 (21.3...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Salem, M., Kvint, S., Hendrix, P., Al Saiegh, F., Gajjar, A., Goren, O., Gross, B., Jabbour, P., Lang, M., Schirmer, C., Tjoumakaris, S., Griessenauer, C., Burkhardt, J. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

P-013 Designing and prototyping a novel balloon-stent device for minimally invasive temporary aneurysm occlusion and embolization
ConclusionA balloon-stent device allows for longer neuro-interventional procedures by providing continuous perfusion without arresting blood flow during balloon inflation. In addition, this novel medical device provides a smooth surface at the aneurysm neck for consistent device placement, minimization of parent vessel trauma, elimination of ischemic effects distal to the parent artery, and minimization of intra-saccular flow remnants pre- and post-treatment.Abstract P-013 Figure 1a) FPR results from theoretical estimation, benchtop modeling, and computational fluid dynamic (CFD) simulation. B) balloon component of the bal...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Asgari, O., Fennell, B., Norris, N., Ducruet, A., Becker, T. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

P-017 Triple therapy versus dual antiplatelet therapy for dolichoectatic vertebrobasilar fusiform aneurysms treated with flow-diverters: the last frontier?
ConclusionsPatients with dolichoectatic VBFAs treated with flow-diversion and kept under triple therapy had less ischemic strokes, less progression of symptoms and overall better outcomes at last follow-up than similar patients kept under DAPT.Disclosures A. Siddiqui: 2; C; Amnis Therapeutics, Apellis Pharmaceuticals, Inc., Boston Scientific, Canon Medical Systems USA, Inc., Cardinal Health 200, LLC, Cerebrotech Medical Systems, Inc., Cerenovus, Cerevatech Medical, Inc.. 4; C; Adona Medical, Inc., Amnis Therapeutics, Bend IT Technologies, Ltd., BlinkTBI, Inc, Buffalo Technology Partners, Inc., Cardinal Consultants, LLC, Ce...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Siddiqui, A., Monteiro, A., Hanel, R., Kan, P., Mohanty, A., Cortez, G., Rabinovich, M., Matouk, C., Sujijantarat, N., Ebersole, K., Fry, L., Natarajan, S., Owusu-Adjei, B., Ortega-Gutierrez, S., Vivanco-Suarez, J., Wakhloo, A., Levy, E. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

E-006 Carotid artery revascularization using the walrus balloon guide catheter: safety and feasibility from a US multicenter experience
ConclusionWalrus BGC for proximal flow-control is safe and effective during eCAS and tCAS. Procedural success was achieved in all cases, with favorable safety and functional outcomes on short term follow-up.Disclosures M. Salem: None. S. Kvint: None. A. Baig: None. A. Monteiro: None. G. Cortez: None. A. Luisa Kuhn: None. O. Goren: None. S. Dalal: None. B. Jankowitz: None. O. Choudhri: None. D. Raper: None. O. Tanweer: None. P. Jabbour: None. R. Starke: None. E. Levy: None. C. Griessenauer: None. A. Puri: None. R. Hanel: None. A. Siddiqui: None. J. Burkhardt: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Salem, M., Kvint, S., Baig, A., Monteiro, A., Cortez, G., Luisa Kuhn, A., Goren, O., Dalal, S., Jankowitz, B., Choudhri, O., Raper, D., Tanweer, O., Jabbour, P., Starke, R., Levy, E., Griessenauer, C., Puri, A., Hanel, R., Siddiqui, A., Burkhardt, J. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-060 Analysis of reported adverse events of flow-diverter stents for intracranial aneurysms using the FDA MAUDE database
ConclusionsPost-market surveillance is an important to guide patient counselling and identify adverse events and device problems that were not identified in initial trials. Although there are inherent limitations to the MAUDE database, our results highlight some important PR and DR complications that can help optimize patient counseling and management.Disclosures M. Porwal: None. G. SenthilKumar: None. D. Kumar: None. G. Sinson: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Porwal, M., SenthilKumar, G., Kumar, D., Sinson, G. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-182 A multicentric experience for the use of flow diverter in the treatment of anterior communicating artery aneurysms
ConclusionFlow diverters appear to be a safe and effective treatment for anterior communicating artery aneurysms, presenting as an alternative strategy in the armamentarium of interventionalist. Mid-term results were favorable, and complication rates were low. Additional studies with longer follow-up time and independent adjudication are warranted to confirm the safety and effectiveness of the technique.Disclosures V. Benalia: None. G. Cortez: None. N. Kocer: None. C. Islak: None. I. Saatci: None. S. Cekirge: None. F. Baltacıoğlu: None. G. Dabus: None. C. Mounayer: None. A. Siddiqui: None. D. Lopes: None. W. ...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Benalia, V., Cortez, G., Kocer, N., Islak, C., Saatci, I., Cekirge, S., Baltacıoglu, F., Dabus, G., Mounayer, C., Siddiqui, A., Lopes, D., Brinjikji, W., Aghaebrahim, A., Sauvageau, E., Hanel, R. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Endoluminal flow diverting stents for middle cerebral artery bifurcation aneurysms: multicenter cohort
Conclusion FDS treatment for MCA bifurcation aneurysms is feasible, with comparable safety and efficacy profiles to other available endovascular options when utilized in carefully selected aneurysms. Jailing of M2 branches was not associated with a higher risk of post-procedural ischemic complications.
Source: Journal of NeuroInterventional Surgery - October 14, 2022 Category: Neurosurgery Authors: Salem, M. M., Khorasanizadeh, M., Lay, S. V., Renieri, L., Kuhn, A. L., Sweid, A., Massari, F., Moore, J. M., Tjoumakaris, S. I., Jabbour, P., Puri, A. S., Ogilvy, C. S., Jankowitz, B. T., Burkhardt, J.-K., Kan, P., Limbucci, N., Cognard, C., Thomas, A. J Tags: Hemorrhagic stroke Source Type: research

Correspondence on "Unplanned readmission after carotid stenting versus endarterectomy: analysis of the United States Nationwide Readmissions Database" by Nazari et al
We read the article by Nazari et al1 comparing carotid endarterectomy and carotid artery stenting. Most of the patients in the article were asymptomatic patients. Asymptomatic carotid stenosis is considered one of the most significant causes of ischemic stroke. The management of asymptomatic carotid stenosis ranges from open surgical approaches to minimally invasive endovascular interventions and medical therapeutics.2 With the advances in the neurosurgical field within the last decade, various surgical interventions have emerged. However, to date, the evidence regarding the optimal interventional strategies for asymptomat...
Source: Journal of NeuroInterventional Surgery - February 14, 2023 Category: Neurosurgery Authors: Azzam, A. Y., Ghozy, S., Kallmes, K. M., Dmytriw, A. A., Kadirvel, R., Kallmes, D. F. Tags: Letter Source Type: research

National reduction in cerebral arteriovenous malformation treatment correlated with increased rupture incidence
Conclusions After 2014, the likelihood of intervention for unruptured AVMs decreased while the incidence of ruptured AVMs increased. These findings suggest that fewer unruptured AVM treatments may lead to increases in AVM rupture incidence.
Source: Journal of NeuroInterventional Surgery - July 14, 2023 Category: Neurosurgery Authors: Luther, E., McCarthy, D. J., Burks, J., Govindarajan, V., Lu, V. M., Silva, M., Lang, M., Gross, B. A., Starke, R. M. Tags: Editor''s choice, Hemorrhagic stroke Source Type: research

Clinical experience with the Bendit steerable microcatheter: a new paradigm for endovascular treatment
Conclusions Our initial clinical experience with the Bendit21 microcatheter demonstrates its usefulness in achieving technical success in patients with challenging neurovascular conditions.
Source: Journal of NeuroInterventional Surgery - July 14, 2023 Category: Neurosurgery Authors: Killer-Oberpfalzer, M., Chapot, R., Orion, D., Barr, J. D., Cabiri, O., Berenstein, A. Tags: Open access, New devices New devices and techniques Source Type: research

O-065 Multicenter investigation into presentation, management and outcome of infectious intracranial aneurysms
ConclusionPatients with IIAs are at high risk of aneurysm rupture or re-hemorrhage despite treatment with antibiotics. Antibiotic failure occurred in 43% of medically treated patients, and failure was associated with 6 times higher odds of mortality in 1 year.Disclosures A. Alawieh: None. L. Dimisko: None. Y. Zohdy: None. H. Saad: None. S. Newman: None. J. Grossberg: None. C. Cawley: None. G. Pradilla: None. C. Fox: None. C. Perez-Vaga: None. J. Burkhardt: None. M. Salem: None. P. Jabbour: None. K. El Naamani: None. R. Schmidt: None. M. Gooch: None. R. Starke: None. A. Abdelsalam: None. V. Lu: None. M. Levitt: None. A. Spi...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Alawieh, A., Dimisko, L., Zohdy, Y., Saad, H., Newman, S., Grossberg, J., Cawley, C., Pradilla, G., Fox, C., Perez-Vaga, C., Burkhardt, J., Salem, M., Jabbour, P., El Naamani, K., Schmidt, R., Gooch, M., Starke, R., Abdelsalam, A., Lu, V., Levitt, M., Spi Tags: SNIS 20th annual meeting oral abstracts Source Type: research

E-125 Clinical outcomes of mechanical thrombectomy in posterior circulation tandem occlusions: multicenter experience
ConclusionMechanical thrombectomy for posterior circulation tandem occlusions is feasible with reasonable clinical outcomes, despite a high rate of rescue stenting.Disclosures M. Salem: None. G. Sioutas: None. M. Mohammaden: None. A. Luisa Kuhn: None. A. Luisa Kuhn: None. A. Luisa Kuhn: None. C. Tschoe: None. M. Tarek: None. A. Dmytriw: None. R. Regenhardt: None. S. Marioni: None. M. AbdalKader: None. G. Cortez: None. V. Srinivasan: None. T. Nguyen: None. S. Tjoumakaris: None. A. Puri: None. V. Pereira: None. J. Rabinov: None. J. Seigler: None. R. Hanel: None. S. Sheth: None. A. Siddiqui: None. E. Levy: None. D. Haussen: N...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Salem, M., Sioutas, G., Mohammaden, M., Luisa Kuhn, A., Luisa Kuhn, A., Luisa Kuhn, A., Tschoe, C., Tarek, M., Dmytriw, A., Regenhardt, R., Marioni, S., AbdalKader, M., Cortez, G., Srinivasan, V., Nguyen, T., Tjoumakaris, S., Puri, A., Pereira, V., Rabino Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

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