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O-016 Aspiration thrombectomy for acute ischemic stroke patients presenting after 6 hours
ConclusionFor patients with late presentation stroke, aspiration thrombectomy with the Penumbra System in anterior circulations is safe and effective. Rates of good functional outcome and all-cause mortality compare favorably to the DAWN and DEFUSE-3 medical management arms.Disclosures A. Hassan: 2; C; GE Healthcare, Genentech, Medtronic, Microvention, Penumbra, Stryker, Cerenovus, Viz.ai, Balt, Scientia. 3; C; GE Healthcare, Genentech, Medtronic, Microvention, Penumbra, Stryker, Cerenovus, Viz.ai, Balt, Scientia. J. Fifi: 1; C; Microvention, Penumbra, Stryker. 2; C; Microvention, Stryker. 4; C; Imperative Care. O. Zaidat:...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Hassan, A., Fifi, J., Zaidat, O. Tags: Oral abstracts Source Type: research

Mechanical thrombectomy beyond the circle of Willis: efficacy and safety of different techniques for M2 occlusions
Conclusion Stent-retrievers and a combined approach for M2 occlusions seem more effective than direct aspiration, but with higher rates of iSAH. This leads to no detectable difference in clinical outcome at 3 months.
Source: Journal of NeuroInterventional Surgery - May 13, 2022 Category: Neurosurgery Authors: Renieri, L., Valente, I., Dmytriw, A. A., Puri, A. S., Singh, J., Nappini, S., Nencini, P., Kaliaev, A., Abdalkader, M., Alexandre, A., Garignano, G., Vivekanandan, S., Fong, R. P., Parra-Farinas, C., Spears, J., Gomez-Paz, S., Ogilvy, C., Regenhardt, R. Tags: Ischemic stroke Source Type: research

E-123 Evaluation of safety and efficacy of transradial access for mechanical thrombectomy inacute ischemic stroke - A single center experience
ConclusionTransradial access for mechanical thrombectomy in acute ischemic stroke is a primary access in tortuous vasculature/posterior circulation strokes and is a good alternative to the femoral approach. This vascular access is especially helpful in patients with posterior circulation strokes, on anticoagulation or with large body habitus.Disclosures A. Kuhn: None. J. Singh: None. K. de Macedo Rodrigues: None. F. Massari: None. F. Massari: None. M. Gounis: 1; C; National Institutes of Health (NIH), the United States – Israel Binational Science Foundation, Anaconda, ApicBio, Axovant, Cerenovus, Cook Medical, Gentui...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Kuhn, A., Singh, J., de Macedo Rodrigues, K., Massari, F., Massari, F., Gounis, M., Puri, A. Tags: Electronic poster abstracts Source Type: research

E-040 Factors associated with failed mechanical thrombectomy in acute ischemic stroke
ConclusionFailed MT was encountered in approximately 12% of cases. The most common location of failed MT was intracranial and this was predominantly due to ICAS. Further studies to evaluate better treatment modalities of ICAS related LVO are warranted.Disclosures O. Lajthia: None. H. Ali: None. R. Neyes: None. E. Almallouhi: None. R. Chalhoub: None. K. Kicielinski: None. J. Lena: None. M. Sattur: None. G. Porto: None. A. Spiotta: None. S. Al Kasab: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Lajthia, O., Ali, H., Neyes, R., Almallouhi, E., Chalhoub, R., Kicielinski, K., Lena, J., Sattur, M., Porto, G., Spiotta, A., Al Kasab, S. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-147 Ephrin receptor beta 1 single nucleotide polymorphisms in association with age in acute stroke patients undergoing thrombectomy
Conclusion193 patients were included in this interim analysis across 23 centers in the United States, between 02/2021 and 11/2021. For the EPHB1 SNP (rs13073658), Table 1 shows the numbers and proportions of patients with varying expressions of the SNP. While no patients 50 or older were homozygous for the SNP, 16% of those under 50 years old were. The potential relationship between EPHB1 SNP and stroke in younger patients requires further evaluation.Abstract E-147 Table 1Disclosures J. Fraser: 1; C; University of Kentucky, American Heart Association. 2; C; Stream Biomedical, Penumbra, Medtronic. 4; C; Fawkes Biotechnology...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fraser, J., Dabney, A., Vicari, J., Rivet, D., Woodward, B., Nanda, A., Fiorella, D., Baltan, S., Sohrabji, F., Pennypacker, K., Kellner, C. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

P-029 Impact of in-hospital delirium on outcomes of acute ischemic stroke
ConclusionsDelirium complicates ~3.5% of AIS admissions, and is associated with increased risk of in-hospital death, longer stay, higher charges and decrease in likelihood of home discharge.Disclosures D. Pujara: None. H. Kamal: None. O. Mir: None. S. Reddy: None. K. Parsha: None. S. Patil: None. B. Gogia: None. P. Rai: None. C. Sitton: None. M. Chen: None. M. Abraham: None. M. Hussain: None. A. Hassan: None. A. Sarraj: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Pujara, D., Kamal, H., Mir, O., Reddy, S., Parsha, K., Patil, S., Gogia, B., Rai, P., Sitton, C., Chen, M., Abraham, M., Hussain, M., Hassan, A., Sarraj, A. Tags: Oral poster abstracts Source Type: research

E-111 Repeat thrombectomy after large vessel occlusion stroke: incidence, clinical and technical outcomes
ConclusionsRepeat EVT for patients with re-occlusion within 30 days of thrombectomy is associated with favorable improvement in NIHSS, similar functional outcomes to patients undergoing single EVT, but has significantly higher risk of hemorrhagic conversion.Disclosures Y. Zohdy: None. H. Saad: None. B. Howard: None. C. Cawley: None. A. Pabaney: None. T. Garzon-Muvdi: None. I. Maier: None. A. Spiotta: None. P. Jabbour: None. S. Wolfe: None. A. Rai: None. J. Kim: None. J. Mascitelli: None. R. Starke: None. A. Shaban: None. S. Yoshimura: None. R. De Leacy: None. P. Kan: None. I. Fragata: None. A. Polifka: None. A. Arthur: Non...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Zohdy, Y., Saad, H., Howard, B., Cawley, C., Pabaney, A., Garzon-Muvdi, T., Maier, I., Spiotta, A., Jabbour, P., Wolfe, S., Rai, A., Kim, J., Mascitelli, J., Starke, R., Shaban, A., Yoshimura, S., De Leacy, R., Kan, P., Fragata, I., Polifka, A., Arthur, A Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-185 Study design and rationale of THUNDER: an acute ischemic stroke study with the penumbra system including thunderbolt aspiration tubing
ConclusionWe report the design of THUNDER—a multicenter prospective study that examines the use of a novel modulated aspiration thrombectomy system in patients with AIS secondary to LVO.Disclosures D. Fiorella: 1; C; Cerenovus, Medtronic, Siemens, Stryker, Microvention, Penumbra. 2; C; Balt, Marblehead, Medtronic, Stryker, Microvention, Penumbra, Cerenovus. K. Woodward: 2; C; Coviden. E. Levy: None. C. Matouk: 2; C; Silk Road Medical, Penumbra, MicroVention-TERUMO, Medtronic, Stryker. 3; C; Silk Road Medical, Penumbra. I. Kaminsky: 3; C; Penumbra. K. Reuland: None. M. Stiefel: None. A. Kansagra: 1; C; Penumbra. 2; C;...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Fiorella, D., Woodward, K., Levy, E., Matouk, C., Kaminsky, I., Reuland, K., Stiefel, M., Kansagra, A., Frei, D. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-121 Evaluation of safety and efficacy of snuffbox (Distal Radial Artery) access for mechanical thrombectomy in acute ischemic stroke
ConclusionSnuffbox (distal radial artery) access for mechanical thrombectomy in acute ischemic stroke is feasible and safe. It represents a good alternative to the traditional femoral approach, especially in cases of posterior circulation strokes, patients on anticoagulation or with large body habitus.Disclosures A. Kuhn: None. J. Singh: None. F. Massari: None. K. de Macedo Rodrigues: None. V. Naragum: None. V. Anagnostakou: None. M. Gounis: 1; C; National Institutes of Health (NIH), the United States – Israel Binational Science Foundation, Anaconda, ApicBio, Axovant, Cerenovus, Cook Medical, Gentuity, Imperative Car...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Kuhn, A., Singh, J., Massari, F., de Macedo Rodrigues, K., Naragum, V., Anagnostakou, V., Gounis, M., Puri, A. Tags: Electronic poster abstracts Source Type: research

Economic evaluation of intravenous alteplase for stroke with the time of onset between 4.5 and 9 hours
Conclusion For patients with AIS with a time of onset between 4.5 and 9 hours, perfusion imaging-guided intravenous alteplase was likely to be cost-effective in China and was cost-effective in the US when compared with placebo.
Source: Journal of NeuroInterventional Surgery - December 14, 2022 Category: Neurosurgery Authors: Chen, J., Liang, X., Tong, X., Han, M., Ji, L., Zhao, S., Hu, Z., Liu, A. Tags: Open access, Socioeconomics Source Type: research

Unplanned readmission after carotid stenting versus endarterectomy: analysis of the United States Nationwide Readmissions Database
Conclusions Readmission is not uncommon after carotid revascularization, occurs more often after CAS, and is predicted by baseline factors and by preventable adverse events at initial admission.
Source: Journal of NeuroInterventional Surgery - February 14, 2023 Category: Neurosurgery Authors: Nazari, P., Golnari, P., Ansari, S. A., Cantrell, D. R., Potts, M. B., Jahromi, B. S. Tags: Open access, Ischemic stroke Source Type: research

O-001 Trends in endovascular mechanical thrombectomy for acute ischemic stroke: a regional comparison analysis using United States national inpatient sample data
ConclusionsThere remain significant regional differences in the outcomes of EVT for AIS. More analysis is required to determine what is driving these differences. More work is needed to ensure optimal and equitable patient outcomes.Abstract O-001 Table 1 Characteristic (p value) East North Central East South Central Middle Atlantic Mountain New England Pacific South Atlantic West North Central West South Central Age in Years Mean (±SD)(p<0.001) 68.69 ± 14.43 67.04 ± 14.85 70.09 ± 14.39 68.72 ± 14.53 70.27 ± 14.92 70.26 ± 14.51 68.81 ± 14.29 69.21 ± 14.51 67...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brake, A., Fry, L., LeBeau, G., Heskett, C., Lei, C., Alkiswani, A., Le, K., De-Stefano, F., Peterson, J., Ebersole, K. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-010 Racial disparity in mechanical thrombectomy utilization: multicenter registry results from 2016-2020
ConclusionsBlack stroke patients underwent MT less frequently than Whites, likely in part due to longer times from LKW to hospital arrival and a lower rate of documented aLVO. Further studies are needed to assess whether extending the MT time window and more aggressive LVO screening protocols mitigate this disparity.Disclosures A. Wallace: None. D. Gibson: 2; C; iSchemaView, Medtronic, Siemens. K. Asif: None. D. Sahlein: 2; C; Medtronic, Microvention, Stryker, Phenox. 3; C; Medtronic. S. Warach: None. T. Malisch: None. M. Lamonte: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Wallace, A., Gibson, D., Asif, K., Sahlein, D., Warach, S., Malisch, T., Lamonte, M. Tags: Oral abstracts Source Type: research

P-039 Flow diverters for treatment of ICA loop dissections or ICA dissections with associated pseudoaneurysm
ConclusionUse of flow diverters, in some cases in conjunction with (carotid) stents, is an effective treatment option for cervical carotid artery dissections, especially loop dissections with or without associated pseudo aneurysms.Disclosures J. Singh: None. A. Kuhn: None. K. de Macedo Rodrigues: None. F. Massari: None. M. Gounis: 1; C; National Institutes of Health (NIH), the United States – Israel Binational Science Foundation, Anaconda, ApicBio, Axovant, Cerenovus, Cook Medical, Gentuity, Imperative Care, InNeuroCo, Magneto, Mic. 2; C; Cerenovus, Imperative Care, phenox, Medtronic Neurovascular, Route 92 Medical, ...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Singh, J., Kuhn, A., de Macedo Rodrigues, K., Massari, F., Gounis, M., Puri, A. Tags: Oral poster abstracts Source Type: research

LB-008 Treatment outcomes for ARUBA eligible brain arteriovenous malformations: a comparison of real-world data from the NVQI-QOD AVM registry to the ARUBA trial
ConclusionOur results suggest that intervention for unruptured brain AVMs at specialized centers across the United States is safe and effective.DisclosuresA. Alrohimi: None. R. Achey: None. R. Abdalla: None. T. Patterson: None. Y. Moazeni: None. P. Rasmussen: None. G. Toth: None. M. Bain: None. S. Ansari: None. S. Hussain: None. N. Moore: None.
Source: Journal of NeuroInterventional Surgery - August 3, 2023 Category: Neurosurgery Authors: Alrohimi, A., Achey, R., Abdalla, R., Patterson, T., Moazeni, Y., Rasmussen, P., Toth, G., Bain, M., Ansari, S., Hussain, S., Moore, N. Tags: SNIS 20th annual meeting late-breaking oral abstracts Source Type: research

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