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Plain language summary of results from ORION-10 and ORION-11: Two studies to learn how well inclisiran works in people with high cholesterol
Future Cardiol. 2023 Jun 6. doi: 10.2217/fca-2022-0133. Online ahead of print.ABSTRACTWHAT IS THIS PLAIN LANGUAGE SUMMARY ABOUT?: This is a summary of the article describing the results of the ORION-10 and ORION-11 studies, which was published in the New England Journal of Medicine in April 2020. The studies included adult participants with atherosclerotic cardiovascular disease (ASCVD). ASCVD happens when the blood vessels that carry blood from the heart to other areas of the body are blocked by fatty build-up (plaque) causing a heart attack, stroke, or other problems. High levels of low-density lipoprotein cholesterol (L...
Source: Atherosclerosis - June 7, 2023 Category: Cardiology Authors: Kausik K Ray R Scott Wright Source Type: research

Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.PMID:36695182 | DOI:10.1161/CIR.0000000000001123
Source: Atherosclerosis - January 25, 2023 Category: Cardiology Authors: Connie W Tsao Aaron W Aday Zaid I Almarzooq Cheryl A M Anderson Pankaj Arora Christy L Avery Carissa M Baker-Smith Andrea Z Beaton Amelia K Boehme Alfred E Buxton Yvonne Commodore-Mensah Mitchell S V Elkind Kelly R Evenson Chete Eze-Nliam Setri Fugar Giul Source Type: research

Heart Disease and Stroke Statistics-2022 Update: A Report From the American Heart Association
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.PMID:35078371 | DOI:10.1161/CIR.0000000000001052
Source: Atherosclerosis - January 26, 2022 Category: Cardiology Authors: Connie W Tsao Aaron W Aday Zaid I Almarzooq Alvaro Alonso Andrea Z Beaton Marcio S Bittencourt Amelia K Boehme Alfred E Buxton April P Carson Yvonne Commodore-Mensah Mitchell S V Elkind Kelly R Evenson Chete Eze-Nliam Jane F Ferguson Giuliano Generoso Jen Source Type: research

Arterial Atherosclerosis: Vascular Surgery Interventions
Am Fam Physician. 2022 Jan 1;105(1):65-72.ABSTRACTAtherosclerotic vascular disease is a leading cause of death worldwide. Atherosclerotic stenosis of the internal carotid or intracranial arteries causes up to 15% of strokes. Peripheral artery disease affects up to one in five people in the United States who are 60 years and older and nearly one-half of those who are 85 years and older. Renal artery stenosis may affect up to 5% of people with isolated hypertension and up to 40% of people with other atherosclerotic diseases. All patients with atherosclerotic vascular disease should receive a comprehensive program of guidelin...
Source: Atherosclerosis - January 14, 2022 Category: Cardiology Authors: Jonathon M Firnhaber C S Powell Source Type: research