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Source: Meta Gene
Countries: Morocco Health
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G894T endothelial nitric oxide synthase polymorphism and ischemic stroke in Morocco
In this study, genotyping with PCR-RFLP and HRM (high resolution melting) methods were conducted on 165 ischemic stroke patients as well as 182 controls. The goal here was to compare genotyping with PCR-RLFP primer sequences of eNOS gene (size<300bp) to HRM. Our data suggests a statistically significant association between G894T eNOS polymorphism and ischemic stroke in recessive, dominant and additive models with P<0.05 and odds ratio of 2.68 (1.08–6.70), 1.78 (1.16–2.73), and 1.71 (1.21–2.43) respectively. In sum, although the sample size is relatively small, it suggests that G894T eNOS polymorphism co...
Source: Meta Gene - November 4, 2014 Category: Genetics & Stem Cells Source Type: research
