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Cost-effectiveness of endovascular thrombectomy with alteplase versus endovascular thrombectomy alone for acute ischemic stroke secondary to large vessel occlusion
CMAJ Open. 2023 May 16;11(3):E443-E450. doi: 10.9778/cmajo.20220096. Print 2023 May-Jun.ABSTRACTBACKGROUND: Recent randomized trials have suggested that endovascular thrombectomy (EVT) alone may provide similar functional outcomes as the current standard of care, EVT combined with intravenous alteplase treatment, for acute ischemic stroke secondary to large vessel occlusion. We conducted an economic evaluation of these 2 therapeutic options.METHODS: We constructed a decision analytic model with a hypothetical cohort of 1000 patients to assess the cost-effectiveness of EVT with intravenous alteplase treatment versus EVT alo...
Source: cmaj - May 16, 2023 Category: General Medicine Authors: Zhikang Ye Ting Zhou Mengmeng Zhang Junwen Zhou Feng Xie Michael D Hill Eric E Smith Jason W Busse Yi Zhang Ying Liu Xin Wang Zhuo Ma Zhuoling An Source Type: research

Self-reported sleep disturbances among people who have had a stroke: a cross-sectional analysis
CMAJ. 2023 Mar 14;195(10):E354-E362. doi: 10.1503/cmaj.221063.ABSTRACTBACKGROUND: Sleep disturbances and their potential association with stroke remains understudied at a population level. We sought to determine the prevalence of sleep disturbances among people who have effects of stroke compared with the general population.METHODS: We used data from people aged 18 years or older who responded to the sleep and chronic disease modules of the 2017-2018 cycle of the Canadian Community Health Survey (CCHS). We measured sleep disturbances by self-reports of having trouble staying awake most or all of the time; either short (<...
Source: cmaj - March 14, 2023 Category: General Medicine Authors: Matthew S Jeffers Alison C Pittman Tetyana Kendzerska Dale Corbett Kathryn S Hayward Yue Chen Source Type: research

Use of linked data to assess the impact of including out-of-hospital deaths on 30-day in-hospital mortality indicators: a retrospective cohort study
CMAJ Open. 2022 Oct 11;10(4):E882-E888. doi: 10.9778/cmajo.20210264. Print 2022 Sep-Oct.ABSTRACTBACKGROUND: The Canadian Institute for Health Information (CIHI) annually reports on health system performance indicators, including various 30-day in-hospital mortality rates. We aimed to assess the impact of including out-of-hospital deaths on 3 CIHI indicators: 30-day acute myocardial infarction (AMI) in-hospital mortality, 30-day stroke in-hospital mortality and hospital deaths following major surgery.METHODS: We followed national cohorts of patients admitted to hospital in 1 of 9 Canadian provinces for AMI, stroke and major...
Source: cmaj - October 11, 2022 Category: General Medicine Authors: Ania Syrowatka Mingyang Li Jing Gu Ling Yin Danielle Rice Yana Gurevich Source Type: research

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