• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Lessons from the Space-2 trial in preventing carotid artery stroke in medically managed patients
The SPACE-2 trial, led by Dr Tilman Reiff1 from Heidelberg University, was a multi-center, randomized, controlled trial including 36 centers in Austria, Germany, and Switzerland. It aimed to directly compare the benefit of intervention vs best medical therapy (BMT) in patients with high-grade asymptomatic carotid artery stenosis. Interventions considered were carotid endarterectomy (CEA) and carotid artery stenting (CAS). Participants were between the ages of 50 and 85  years with at least 70% internal carotid artery stenosis.
Source: Journal of Vascular Surgery - March 7, 2023 Category: Surgery Authors: Young Erben, Thomas G. Brott Source Type: research

The Challenge of Preventing Carotid Artery Stroke in Properly Medically Managed Patients: Lessons From SPACE-2
The SPACE-2 trial led by Dr. Tilman Reiff(1) from Heidelberg University was a multi-center, randomized, controlled trial including 36 centers in Austria, Germany and Switzerland. It aimed to directly compare the benefit of intervention versus best medical therapy (BMT) in high-grade asymptomatic carotid artery stenosis patients. Interventions considered were carotid endarterectomy (CEA) and carotid artery stenting (CAS). Participants were between the ages of 50 and 85 years with at least 70% internal carotid artery stenosis.
Source: Journal of Vascular Surgery - March 7, 2023 Category: Surgery Authors: Young Erben, Thomas G. Brott Source Type: research

Important recommendations of the German-Austrian S3 guidelines on management of extracranial carotid artery stenosis
CONCLUSION: Both CEA and CAS necessitate a critical evaluation of the indications and strict quality criteria. Future studies should evaluate even better selection criteria for an individual, optimal, conservative, operative or endovascular treatment.PMID:35318494 | DOI:10.1007/s00104-022-01622-x
Source: Der Chirurg - March 23, 2022 Category: Surgery Authors: Hans-Henning Eckstein Andreas K ühnl Michael Kallmayer Source Type: research

Impact of metabolic surgery on cost and long-term health outcome: a  cost-effectiveness approach
CONCLUSION: MS is associated with substantial savings in long-term costs, expected health benefits, and reduced onset of complications. MS significantly increases quality of life.PMID:34782294 | DOI:10.1016/j.soard.2021.10.012
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - November 16, 2021 Category: Surgery Authors: Evelyn Walter Felix B Langer Philipp Beckerhinn Franz Hoffer Gerhard Prager Source Type: research