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Comparison of Echocardiographic Parameters of Left Atrial and Ventricular Function between Young Stroke vs Lone Atrial Fibrillation vs Healthy Controls
Background: Stroke is one of Australia's leading causes of morbidity and mortality with a significant percentage classified as cryptogenic. The nature and aetiology of cryptogenic stroke remains elusive, with a proportion believed to be cardio-embolic secondary to subclinical paroxysmal atrial fibrillation (AF). We aim to gain mechanistic insights into the pathophysiology of cryptogenic stroke in the young by comparing cardiac structural and functional differences in patients with young stroke, lone AF and healthy controls.
Source: Heart, Lung and Circulation - June 23, 2019 Category: Cardiology Authors: A. Bhat, S. Khanna, H. Chen, G. Gan, R. MacIntyre, T. Tan Tags: 254 Source Type: research

Stroke Risk Factors and Outcomes in Indigenous Verse Non-Indigenous Australians
Background: Stroke risk factors are well known, but there is little data on the prevalence of stroke risk factors in Indigenous Australian cohorts. We aim to assess the risk factors and the outcomes after stroke and compare these in Indigenous and non-Indigenous Australians presenting with acute strokes to the Wagga Wagga Rural Referral Hospital.
Source: Heart, Lung and Circulation - May 24, 2019 Category: Cardiology Authors: Angela Dos Santos, Katherine Mohr, Martin Jude, Neil Simon, Candice Delcourt Tags: P20 Source Type: research

414 The Diagnostic Value of Inpatient Transthoracic Echocardiography for Stroke and TIA
Australian guidelines for ischaemic stroke recommend echocardiography for select patients in whom stroke aetiology is unclear after initial investigations.1 We sought to identify whether inpatient echocardiograms for investigation of stroke/TIA aetiology were appropriately utilised according to this recommendation.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: M. Maffey, S. Nguyen, S. Wahi Source Type: research

Cardiac Rehabilitation: Are People With Stroke or Transient Ischaemic Attack Being Included? A Cross-Sectional Survey
Cardiac rehabilitation (CR) may be an effective secondary prevention program for people with stroke or transient ischaemic attack (TIA). The aims of this study were to determine whether people with stroke or TIA were attending CR in Australia and if there were any barriers to attendance.
Source: Heart, Lung and Circulation - April 10, 2019 Category: Cardiology Authors: Tom Howes, Niru Mahenderan, Nicole Freene Tags: Original Article Source Type: research

Stroke Incidence and Outcomes in Indigenous Australians
We present the first prospective population-based pilot study of stroke incidence and outcomes in Indigenous Australians.
Source: Heart, Lung and Circulation - May 24, 2019 Category: Cardiology Authors: Angela Dos Santos, Anna Balabanski, Tim Kleinig, Amanda Thrift, Alex Brown, Judith Katzenellenbogen, Edmung Cheong Tags: P19 Source Type: research

Is Incorrect Anti-Coagulation Dosing Contributing to Ischaemic Stroke Burden? A Retrospective Single-Centre Study from Regional New South Wales, Australia
Background: Atrial fibrillation (AF) contributes to 30% of ischaemic stroke presentations. Low doses of anti-coagulants are often prescribed to prevent stroke but ameliorate bleeding risk.
Source: Heart, Lung and Circulation - June 23, 2019 Category: Cardiology Authors: P. Bamford, M. Ray, S. Cheruvu, M. Parkinson, C. Said, J. Trappel, J. Rogers Tags: 195 Source Type: research

Time Trends in Stroke Risk Management Among Patients With Atrial Fibrillation in Australia Between 2011 –2019
This study examined management among Australian patients between 2011 –2019.
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: K. Giskes, N. Lowres, J. Orchard, K. Hyun, C. Hespe, B. Freedman Source Type: research

Underusage of Oral Anticoagulation in Atrial Fibrillation: Can We Prevent More Strokes?
Atrial fibrillation (AF) is the most common sustained arrhythmia in Australia, affecting 2% of the population, and 6% of those over the age of 55 years [1]. The greatest contributor to morbidity and mortality in AF is its association with ischaemic stroke [2]. AF increases the risk of cardioembolic stroke five-fold, with an annual incidence of up to 7% [3]. There have been several validated tools developed to help individualise stroke risk, such as the CHADS2 [4], CHA2DS2-VASc [5], and more recently the CHA2DS2-VA score [6], all of which require the input of several vascular risk factors.
Source: Heart, Lung and Circulation - June 2, 2021 Category: Cardiology Authors: Karan Rao, Ravinay Bhindi Tags: Editorial Source Type: research

NOACs Now Mainstream for the Use of Anticoagulation in Non-Valvular Atrial Fibrillation in Australia.
The management of stroke risk in patients with non-valvular atrial fibrillation has changed over the past few years. This change has occurred due to the introduction of novel oral anticoagulants (NOACs) such as apixaban, rivaroxaban and dabigatran for the management of non-valvular atrial fibrillation. These agents have shown comparable stroke risk reduction to warfarin in large international multicentre trials [1 –3]. This has changed the clinical practice of many treating physicians since their introduction from 2011 to 2013.
Source: Heart, Lung and Circulation - March 22, 2018 Category: Cardiology Authors: Derk Pol, Claire Curtis, Satish Ramukumar, Logan Bittinger Tags: Brief Communication Source Type: research

NOACs Now Mainstream for the Use of Anticoagulation in Non-Valvular Atrial Fibrillation in Australia
The management of stroke risk in patients with non-valvular atrial fibrillation has changed over the past few years. This change has occurred due to the introduction of novel oral anticoagulants (NOACs) such as apixaban, rivaroxaban and dabigatran for the management of non-valvular atrial fibrillation. These agents have shown comparable stroke risk reduction to warfarin in large international multicentre trials [1 –3]. This has changed the clinical practice of many treating physicians since their introduction from 2011 to 2013.
Source: Heart, Lung and Circulation - March 22, 2018 Category: Cardiology Authors: Derk Pol, Claire Curtis, Satish Ramukumar, Logan Bittinger Tags: Brief Communication Source Type: research

Atrial Fibrillation and Indigenous Australians: A way Forward for Timely and Effective Screening and Treatment
Background: The leading cause of death for Indigenous Australians is cardiovascular disease, including stroke. Atrial Fibrillation (AF) increases stroke risk 5 –7 fold. Early detection and treatment of AF in Caucasians has proven feasible. Aim: To estimate AF prevalence in community settings and examine feasibility of using a handheld single-lead ECG device (iECG) for Indigenous Australians.
Source: Heart, Lung and Circulation - June 23, 2019 Category: Cardiology Authors: K. Gwynne, J. Gwynn, H. Finlayson, S. Hamilton, M. Lawrence, R. MacNiven, L. Neubeck, B. Rambaldini, R. Rodrigues, K. Taylor, S. Thompson, B. Freedman Tags: 514 Source Type: research

Predictors of Anticoagulation Use in Indigenous and Non-Indigenous Australians with Atrial Fibrillation
Prior studies have demonstrated that anticoagulation underutilisation for atrial fibrillation (AF) and elevated stroke risk is common. However, there is little data on factors associated with appropriate anticoagulation, particularly in Indigenous Australians who face a disproportionate burden of AF and stroke. We thus sought to determine factors associated with anticoagulation use in Australians with AF.
Source: Heart, Lung and Circulation - October 29, 2020 Category: Cardiology Authors: Simon Rocheleau, Celine Gallagher, Bradley M. Pitman, Samuel J. Tu, Nicole Hanna-Rivero, Nicholas Clarke, Dominik Linz, Jeroen M. Hendriks, Melissa E. Middeldorp, Rajiv Mahajan, Dennis H. Lau, Kurt C. Roberts-Thomson, Prashanthan Sanders, Christopher X. W Tags: Original Article Source Type: research

Oral Anticoagulant Use in Patients With Atrial Fibrillation and Chronic Kidney Disease: A Review of the Evidence With Recommendations for Australian Clinical Practice
Chronic kidney disease is common in patients with atrial fibrillation (AF) and is associated with heightened risks of stroke/systemic embolisation and bleeding. In this review we outline the evidence for AF stroke prevention in kidney disease, identify current knowledge gaps, and give recommendations for anticoagulation at various stages of chronic kidney disease.Overall, anticoagulation is underused. Warfarin use becomes increasingly difficult with advancing kidney disease, with difficulty maintaining international normalised ratio (INR) in therapeutic range, increased risk of intracranial and fatal bleeding compared to n...
Source: Heart, Lung and Circulation - November 3, 2022 Category: Cardiology Authors: Christopher Hammett, Sunil V. Badve, Peter G. Kerr, Huyen A. Tran, Benjamin K. Dundon, Sidney Lo, Andrew Wong, Joanne E. Joseph, Jenny Deague, Vlado Perkovic Tags: Review Source Type: research

Older People With Atrial Fibrillation and Hypertension Are at Higher Risk of Poor Blood Pressure Control in Australian Primary Care
This study explored factors that influence BP control in AF patients with hypertension managed in Australian primary care, with a focus on older age.
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: R. Trivedi, T. Shaw, C. Chow, L. Laranjo Source Type: research

Comorbidities and Ventricular Dysfunction Drive Excess Mid-Term Morbidity in an Indigenous Australian Coronary Revascularisation Cohort
There is a paucity of data in regards to longer term morbidity outcomes in Indigenous Australian patients undergoing coronary artery bypass grafting (CABG). No comparative data on re-infarction, stroke or reintervention rates exist. Outcome data following percutaneous coronary intervention (PCI) is also extremely limited. Addressing this gap in knowledge forms the major aim of our study.
Source: Heart, Lung and Circulation - April 24, 2018 Category: Cardiology Authors: Paul D Wiemers, Lucy Marney, Nicole White, Georgina Bough, Alistair Hustig, Wei Tan, Ching-Siang Cheng, Dong Kang, Sumit Yadav, Robert Tam, John F Fraser Tags: Original Article Source Type: research

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