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Diagnostics and Treatments of Iron-Related CNS Diseases.
Authors: Xiong H, Tuo QZ, Guo YJ, Lei P Abstract Iron has been proposed to be responsible for neuronal loss in several diseases of the central nervous system, including Alzheimer's disease (AD), Parkinson's disease (PD), stroke, Friedreich's ataxia (FRDA), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS). In many diseases, abnormal accumulation of brain iron in disease-affected area has been observed, without clear knowledge of the contribution of iron overload to pathogenesis. Recent evidences implicate that key proteins involved in the disease pathogenesis may also participate in cellular iron metabol...
Source: Advances in Experimental Medicine and Biology - August 29, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research