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Condition: Arteriosclerosis
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Sulfur amino acids and atherosclerosis: a role for excess dietary methionine
The homocysteine theory of arteriosclerosis received credence when it was shown that after a methionine load, circulating homocysteine–cysteine concentrations were higher in cardiovascular disease patients than in healthy controls. Subsequent studies showing associations between homocysteine and coronary artery disease, stroke and cognitive impairment, relied on small increases in homocysteine concentration unlike the very high homocysteine seen in the rare genetic disorders that lead to homocystinuria and much higher homocysteine levels. Subsequent studies in cell culture, animals, and humans showed that a variety of ca...
Source: Annals of the New York Academy of Sciences - December 8, 2015 Category: Science Authors: Jacob Selhub, Aron M. Troen Tags: Original Article Source Type: research
