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Source: International Journal of Cardiology
Condition: Aortic Stenosis
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Total 20 results found since Jan 2013.
TAVI for patients with normal-flow low-gradient compared to high-gradient aortic stenosis
Normal-flow (stroke volume index, SVi>35 ml/m2) low-gradient (dPmean
Source: International Journal of Cardiology - October 24, 2022 Category: Cardiology Authors: Julius Steffen, David Andreae, Michael Nabauer, Nikolas Rei ßig, Philipp M. Doldi, Magda Haum, Martin Orban, Hans Theiss, Konstantinos Rizas, Daniel Braun, Sven Peterß, Jörg Hausleiter, Steffen Massberg, Simon Deseive Source Type: research
Implementation of a CT-derived correction factor to refine the measurement of aortic valve area and stroke volume using Doppler echocardiography improves grading of severity and prediction of prognosis in patients with severe aortic stenosis
Aims: To assess rates of reclassification of severity and associated 5-year survival in patients with severe aortic stenosis (AS) and preserved left ventricular ejection fraction (LVEF) after application of a CT-derived correction factor (CF) to refine the measurement of aortic valve area (AVA) and stroke volume index (SVi) using Doppler echocardiography.Methods and Results: We enrolled 1450 patients with severe AS and preserved LVEF from a French registry. Multiplication of echocardiographic LV outflow tract diameter by a CT-derived CF of 1.13 to calculate the AVA and SVi using the continuity equation resulted in reclassi...
Source: International Journal of Cardiology - June 15, 2022 Category: Cardiology Authors: Attila Kardos, Dan Rusinaru, Sylvestre Mar échaux, Ebraham Alskaf, Bernard Prendergast, Christophe Tribouilloy Source Type: research
Simplifying the approach to classical low-flow low-gradient severe aortic stenosis: A renewed emphasis on the resting transthoracic echocardiogram
Aortic stenosis (AS) represents the most commonly encountered valvular heart disease. Traditionally, severe AS is defined by an aortic valve area (AVA) less than or equal to 1.0 cm2 and mean aortic valve gradient (MG) greater than or equal to 40 mm Hg. In roughly 40% of encountered cases, however, Doppler echocardiography yields discordant findings—a calculated AVA suggestive of severe AS but a MG consistent with less-than-severe disease [1,2]. Assuming no error in measurement, these cases stem, in part, from low-flow states (defined as a resting stroke volume index, SVI, less than or equal to 35 mL/m2) and cons...
Source: International Journal of Cardiology - March 22, 2021 Category: Cardiology Authors: James W. Lloyd, Mackram F. Eleid Tags: Editorial Source Type: research
Allometric versus ratiometric normalization of left ventricular stroke volume by Doppler-echocardiography for outcome prediction in severe aortic stenosis with preserved ejection fraction
Appropriate normalization methods to scale Doppler-derived stroke volume (SV) to body size in patients with aortic stenosis (AS) are poorly defined and reference values are lacking. We aim to establish reference values of normalized SV in adults, and to compare the prognostic value of SV normalized by different methods in AS patients.
Source: International Journal of Cardiology - October 8, 2019 Category: Cardiology Authors: Dan Rusinaru, Ernst R. Rietzschel, Yohann Bohbot, Marc L. De Buyzere, Otilia Buiciuc, Sylvestre Mar échaux, Thierry C. Gillebert, Christophe Tribouilloy Source Type: research
Impact of stroke volume assessment by integrating multi-detector computed tomography and Doppler data on the classification of aortic stenosis
The prevalence of low flow low gradient (LFLG) severe aortic stenosis (AS) may be overrated due to underestimation of stroke volume in two-dimensional (2D) echocardiography. The implications of 3D imaging on stroke volume calculation for AS classification have not been elucidated. Integrating multi-detector computed tomography (MDCT) and Doppler data may improve diagnostic accuracy in patients with LFLG AS.
Source: International Journal of Cardiology - September 1, 2017 Category: Cardiology Authors: Barbara E. St ähli, Thomas Stadler, Erik W. Holy, Thi Dan Linh Nguyen-Kim, Lisa Hoffelner, Ladina Erhart, Slayman Obeid, Markus Niemann, Rolf Jenni, Sandra Hamada, Robert Manka, Thomas F. Lüscher, Francesco Maisano, Fabian Nietlispach, Thomas Frauenfeld Source Type: research
Extracranial carotid artery stenosis and outcomes of patients undergoing transcatheter aortic valve replacement
Transcatheter aortic valve replacement (TAVR) is an alternative to open cardiac surgery in selected patients with severe aortic stenosis (AS). Carotid artery stenosis (CAS) has been associated with an increased risk of stroke following cardiac surgery, although the association between CAS and outcomes following TAVR is unclear. We therefore sought to study the prognostic impact of CAS on outcomes of patients undergoing TAVR.
Source: International Journal of Cardiology - November 7, 2016 Category: Cardiology Authors: Jeremy Ben-Shoshan, David Zahler, Arie Steinvil, Shmuel Banai, Gad Keren, Natan M. Bornstein, Ariel Finkelstein, Amir Halkin Source Type: research
Valve thrombosis 3 years after transcatheter aortic valve implantation
An 81year old male underwent transcatheter aortic valve implantation (TAVI) with a 31mm CoreValve (Medtronic Inc., Minneapolis, Minnesota) and PCI 3years ago for the treatment of symptomatic severe aortic stenosis and tight left main stenosis. The patient's comorbidities included coronary artery disease with a history of PCI, a history of stroke, and a longstanding hypertension. Ejection fraction was normal and the patient was in sinus rhythm. The procedure was uneventful, mean transaortic gradient decreased from 43 to 7mmHg, and there was mild paravalvular regurgitation.
Source: International Journal of Cardiology - January 8, 2016 Category: Cardiology Authors: Stefan Toggweiler, Kai Schmidt, Matthias Paul, Florim Cuculi, Richard Kobza, Peiman Jamshidi Source Type: research
Valve thrombosis 3years after transcatheter aortic valve implantation
An 81year old male underwent transcatheter aortic valve implantation (TAVI) with a 31mm CoreValve (Medtronic Inc., Minneapolis, Minnesota) and PCI 3years ago for the treatment of symptomatic severe aortic stenosis and tight left main stenosis. The patient's comorbidities included coronary artery disease with a history of PCI, a history of stroke, and a longstanding hypertension. Ejection fraction was normal and the patient was in sinus rhythm. The procedure was uneventful, mean transaortic gradient decreased from 43 to 7mmHg, and there was mild paravalvular regurgitation.
Source: International Journal of Cardiology - January 8, 2016 Category: Cardiology Authors: Stefan Toggweiler, Kai Schmidt, Matthias Paul, Florim Cuculi, Richard Kobza, Peiman Jamshidi Tags: Correspondence Source Type: research
Diastolic dysfunction reduces stroke volume during daily's life activities in patients with severe aortic stenosis
Pathophysiologic consequences of left ventricular (LV) hypertrophy and fibrosis, as these occur in aortic stenosis, are elevated filling and left atrial (LA) pressures [1]. Depending on the time duration of pressure overload, LA volume increases proportionally to the degree of left ventricular (LV) diastolic dysfunction [2]. Elevated LA pressure aims to ensure adequate LV filling and, consequently, stroke volume but may return to normal levels during certain daily activities (e.g., cough, defecation, lifting a heavy or even medium load), which produce a preload reduction, possibly compromising LV both filling and stroke volume [1].
Source: International Journal of Cardiology - May 20, 2015 Category: Cardiology Authors: Maria Angela Losi, Raffaele Izzo, Eugenio Stabile, Anna Sannino, Grazia Canciello, Alessandra Giamundo, Francesca Musella, Plinio Cirillo, Mariella Prastaro, Maurizio Galderisi, Bruno Trimarco, Giovanni Esposito Tags: Letter to the Editor Source Type: research
Echo-doppler and invasive evaluation of valvulo-arterial impedance in patients with severe aortic stenosis: Impact of pressure recovery
Aortic stenosis (AS) is the most frequent valvulopathy in the western population [1]. Guidelines reported eco-Doppler mean (MG) and peak (PG) gradient and valve area (AVA) as index to its quantitative evaluation [2]. However, they seem inadequate to a correct severity definition [3] and new parameters, such as valvulo-arterial impedance (Zva), an index of global LV afterload, which theoretically accounts for the effects of AS and systemic arterial compliance [4], have been proposed [5]. Zva is obtained as the ratio of stroke volume index (SVI) to the sum of systolic arterial pressure (SAP) and MG [6] and for its correct e...
Source: International Journal of Cardiology - October 24, 2014 Category: Cardiology Authors: Corinna Bergamini, Giorgio Golia, Aldo D. Milano, Matteo Pernigo, Francesca Vassanelli, Gabriele Pesarini, Giuseppe Faggian, Corrado Vassanelli Tags: Letter to the editor Source Type: research
Time to peak velocity of aortic flow is useful in predicting severe aortic stenosis
Echocardiography has been the gold standard method to evaluate the severity of aortic valvular stenosis (AS) in clinical practice. The calculation of aortic valve area (AVA) by continuity equation is reliable and has been extensively studied in past publications . To get the correct AVA by continuity equation, the following parameters must be reliably measured: 1) left ventricular (LV) outflow tract (LVOT) diameter (LVOTd); 2) pulsed wave Doppler signal of the blood flow in the LVOT; and 3) continuous wave Doppler signal of the blood flow at the stenotic aortic valve . However, these measurements could not always be satisf...
Source: International Journal of Cardiology - February 3, 2014 Category: Cardiology Authors: Sung Hea Kim, Je Sang Kim, Bum Sung Kim, Jinoh Choi, Sang-Chol Lee, Jae K. Oh, Seung Woo Park Tags: Online Letters to the Editor Source Type: research
Successful management of a twice complicated case by implantation of three CoreValve prostheses
An 80year old man, diabetic on oral medication and with permanent atrial fibrillation with a single chamber pacemaker, was referred to our hospital for severe symptomatic aortic valve stenosis. His trans-thoracic echocardiography confirmed severe aortic stenosis with a mean/peak gradient of 45/85mmHg, an estimated aortic valve area of 0.7cm2 and good systolic function with an ejection fraction of 50%. His past medical history was remarkable for a minor stroke without neurological impairment and moderate kidney dysfunction with creatinine of 2.3mg/dL. A cardiac catheterization revealed no obstructive coronary heart disease.
Source: International Journal of Cardiology - January 27, 2014 Category: Cardiology Authors: George Latsios, Kostantinos Toutouzas, Dimitris Tousoulis, Andreas Synetos, Antonios Mastrokostopoulos, Konstantinos Stathogiannis, Themis Spyridopoulos, Ulrich Gerckens, Christodoulos Stefanadis Tags: Letters to the Editor Source Type: research
The Ibero-American transcatheter aortic valve implantation registry with the CoreValve prosthesis. Early and long-term results
Conclusions: Transcatheter aortic valve implantation constitutes a safe and viable therapeutic option for high operative risk patients with severe aortic stenosis. Long-term prognosis is conditioned by associate comorbidities.
Source: International Journal of Cardiology - October 15, 2013 Category: Cardiology Authors: Antonio J. Muñoz-García, Raquel del Valle, Ramiro Trillo-Nouche, Jaime Elízaga, Federico Gimeno, Rosana Hernández-Antolín, Rui Teles, Vasco de Gama Ribeiro, Eduardo Molina, Ángel Cequier, Cristóbal Urbano-Carrillo, Ignacio Cruz-González, Miguel Pa Tags: Original Articles Source Type: research
MSCT guided sizing of the Edwards Sapien XT TAVI device: Impact of different degrees of oversizing on clinical outcome
Abstract: Aims: Prospective data on the usage of 3-dimensional imaging based annulus sizing on the outcome of TAVI is not available yet and there is general uncertainty about the optimal degree of oversizing. In the current study we therefore assessed a 3-D MSCT guided over-sizing approach and evaluated the clinical outcome of different degrees of oversizing.Methods: TAVI-size-selection was done using systolic MSCT-annulus cross-sectional-area (CSA) measurements in 107 patients with severe aortic stenosis with the goal to oversize the 3rd generation balloon expandable Edwards Sapien XT (ESTV) device in relation to the nati...
Source: International Journal of Cardiology - April 15, 2013 Category: Cardiology Authors: A.W. Leber, W. Eichinger, J. Rieber, M. Lieber, S. Schleger, U. Ebersberger, M. Deichstetter, J. Vogel, T. Helmberger, D. Antoni, G. Riess, E. Hoffmann, A.M. Kasel Tags: Original Articles Source Type: research
Impact of global hemodynamic load on exercise capacity in aortic stenosis
Abstract: Background: The determinants of maximal exercise capacity (MEC) in aortic stenosis (AS) are, in large part, unknown. We hypothesized that the left ventricular (LV) global hemodynamic load – as assessed by the valvulo-arterial impedance (Zva) – is one of the main determinants of MEC and we sought to evaluate the factors associated with reduced MEC in AS.Method and results: Asymptomatic patients with moderate or severe AS (n=62, aortic valve area 50%) were prospectively referred for comprehensive resting echocardiography and cardiopulmonary exercise test. Absolute peak VO2 was 19.5±5.7mL/kg/min (median 19.6mL/...
Source: International Journal of Cardiology - March 1, 2013 Category: Cardiology Authors: R. Dulgheru, J. Magne, R. Capoulade, L. Davin, D. Vinereanu, L.A. Pierard, P. Pibarot, P. Lancellotti Tags: Original Articles Source Type: research
