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Associations between long-term serum platinum and neurotoxicity and ototoxicity, endocrine gonadal function, and cardiovascular disease in testicular cancer survivors.
CONCLUSION: Median 19 years after treatment, increasing quartiles of se-Pt are associated with increasing SCIN score, tinnitus, hearing impairment, and increasing LH levels. However, these associations remained significant only for tinnitus and LH when adjusting for administered cisplatin dose. PMID: 27523611 [PubMed - as supplied by publisher]
Source: Urologic Oncology - August 10, 2016 Category: Urology & Nephrology Authors: Hjelle LV, Bremnes RM, Gundersen PO, Sprauten M, Brydøy M, Tandstad T, Wilsgaard T, Fosså SD, Oldenburg J, Haugnes HS Tags: Urol Oncol Source Type: research