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Condition: Thrombosis
Therapy: Thrombolytic Therapy
Nutrition: Sodium Chloride
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Total 2 results found since Jan 2013.
Plasma Kallikrein Contributes to Intracerebral Hemorrhage and Hypertension in Stroke-Prone Spontaneously Hypertensive Rats
This report investigates the role of PKa on hemorrhage and hypertension in stroke-prone spontaneously hypertensive rats (SHRSP). SHRSP were fed with a high salt-containing stroke-prone diet to increase blood pressure and induce intracerebral hemorrhage. The roles of PKa on blood pressure, hemorrhage, and survival in SHRSP were examined in rats receiving a PKa inhibitor or plasma prekallikrein antisense oligonucleotide (PK ASO) compared with rats receiving control ASO. Effects on PKa on the proteolytic cleavage of atrial natriuretic peptide (ANP) were analyzed by tandem mass spectrometry. We show that SHRSP on high-salt die...
Source: Cell Research - July 9, 2021 Category: Cytology Authors: Jian Guan Allen C Clermont Loc-Duyen Pham Tuna Ustunkaya Alexey S Revenko A Robert MacLeod Edward P Feener Fabr ício Simão Source Type: research
