• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Cerebral air embolism during CT-guided lung biopsy
A patient with cirrhosis and hepatocellular carcinoma, on the waiting list for liver transplantation, presented with lung nodule during initial evaluation. A CT-guided core needle lung biopsy under general anaesthesia was performed. Pneumothorax (figure 1) and a large amount of gas within the left ventricle (figure 2) were identified during the procedure. Neurological focal signs (drowsiness, conjugate eye deviation and right hemiparesis) were observed in the anaesthesia-recovery period. A brain CT scan was immediately obtained, showing cerebral air embolism (figure 3). Initial resuscitation and hyperbaric oxygen therapy w...
Source: Thorax - October 14, 2015 Category: Respiratory Medicine Authors: Rocha, R. D., Azevedo, A. A., Falsarella, P. M., Rahal, A., Garcia, R. G. Tags: Images in Thorax, Journalology, Screening (oncology), Venous thromboembolism, Pulmonary embolism, Transplantation, Ethics Chest clinic Source Type: research

What's hot that the other lot got
Fibrinolysis for patients with intermediate-risk PE The use of fibrinolysis for normotensive patients with an intermediate risk of death after acute pulmonary embolism (PE) remains a controversial topic. The PIETHO trial (N Engl J Med 2014;370:1402–11) was a multicentre, double-blind trial, in which 1006 patients with acute PE and evidence of right ventricular dysfunction on echocardiography or CT, as well as positive cardiac troponin test, were randomly assigned to initial treatment with tenecteplase plus heparin, or placebo plus heparin. The primary outcome of death or haemodynamic compromise within 7 days of rando...
Source: Thorax - May 14, 2014 Category: Respiratory Medicine Authors: Rolin, S. Tags: Clinical trials (epidemiology), Epidemiologic studies, Drugs: infectious diseases, HIV/AIDS, Inflammation, Venous thromboembolism, Pulmonary embolism, Radiology (diagnostics) Chest clinic Source Type: research

Management dilemmas in acute pulmonary embolism
Conclusion The suggested approaches are based on a review of the available evidence and guidelines and on our clinical experience. Management in an individual patient requires clinical assessment of risks and benefits and also depends on local availability of therapeutic interventions.
Source: Thorax - January 15, 2014 Category: Respiratory Medicine Authors: Condliffe, R., Elliot, C. A., Hughes, R. J., Hurdman, J., Maclean, R. M., Sabroe, I., van Veen, J. J., Kiely, D. G. Tags: Open access, Venous thromboembolism, Pulmonary embolism Review Source Type: research