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Thrombosis origin identification of cardioembolism and large artery atherosclerosis by distinct metabolites
Conclusions Six metabolites as potential predictors for distinguishing between cerebral thrombi of CE and LAA origin were identified. The results are useful for understanding the pathogenesis and for secondary stroke prevention.
Source: Journal of NeuroInterventional Surgery - June 16, 2023 Category: Neurosurgery Authors: Li, W., Bai, X., Hao, J., Xu, X., Lin, F., Jiang, Q., Ding, C., Dai, G., Peng, F., Zhang, M., Feng, Y., Wang, J., Chen, X., Xue, T., Guo, X., Fu, Z., Chen, W.-h., Zhang, L., Wang, C., Jiao, L. Tags: Basic science Source Type: research

Impedance-based sensors discriminate among different types of blood thrombi with very high specificity and sensitivity
Conclusions Combining EIS measurements with machine learning provides a highly effective approach for discriminating among different thrombus types and liquid blood. These findings raise the possibility of developing a probe-like device (eg, a neurovascular guidewire) integrating an impedance-based sensor. This sensor, placed in the distal part of the smart device, would allow the characterization of the probed thrombus on contact. The information could help physicians identify optimal thrombectomy strategies to improve outcomes for stroke patients.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Messina, P., Garcia, C., Rambeau, J., Darcourt, J., Balland, R., Carreel, B., Cottance, M., Gusarova, E., Lafaurie-Janvore, J., Lebedev, G., Bozsak, F., Barakat, A. I., Payrastre, B., Cognard, C. Tags: Open access, Ischemic stroke Source Type: research

E-033 variety of clot types and their implication on technique during endovascular stroke therapy
ConclusionOur data indicate that thrombectomy with a stent-retriever and balloon guide system provides the best opportunity for good outcomes. Because of the risks of shearing off part or all of a clot when aspirating an oversized thrombus into an intermediate catheter and further retrieving against the flow in the internal carotid, our strategy is to use intermediate catheters in conjunction with a balloon guide whenever possible to achieve flow-arrest. We did not have a large enough sample size to draw conclusions about the impact of technique on the number of passes. Further evaluation of how to optimize techniques in d...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Andersson, T. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research