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Low Incidence of Ischemic Stroke Associated With Thrombus Aspiration in STEMI Patients Undergoing Primary PCI
CONCLUSIONS: Very low stroke rates immediately post STEMI were seen in patients undergoing TA and PPCI in this real-world study. TA can be performed safely in STEMI patients undergoing PPCI with a short-term stroke risk equivalent to risk without TA. Further studies may be needed to explain the increased incidence of late stroke noted after TA and elucidate causative mechanisms.PMID:34433694
Source: The Journal of Invasive Cardiology - August 26, 2021 Category: Cardiology Authors: Siddharth J Trivedi Mark J Cooper Andrew T L Ong A Robert Denniss Source Type: research

Initial Experience With GlideAssist to Facilitate Advancement of Orbital Atherectomy Prior to Plaque Modification of Severely Calcified Coronary Artery Lesions.
CONCLUSIONS: The GlideAssist function is a useful feature of the orbital atherectomy system to facilitate successful delivery of the crown in complex coronary anatomy. PMID: 31671058 [PubMed - in process]
Source: The Journal of Invasive Cardiology - November 2, 2019 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Outcomes of Orbital Atherectomy in Severely Calcified Small (2.5 mm) Coronary Artery Vessels.
CONCLUSIONS: Orbital atherectomy followed by stenting of small-diameter vessels appears to be feasible and safe. Further studies are needed to determine the ideal revascularization strategy for these patients. PMID: 30068786 [PubMed - in process]
Source: The Journal of Invasive Cardiology - August 3, 2018 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Safety of Percutaneous Coronary Intervention Without P2Y12 Inhibitor Pretreatment From a Cohort of Unselected Patients.
CONCLUSIONS: In an unselected population admitted for elective PCI or NSTEMI in real-world clinical practice, administration of a P2Y12 inhibitor only after coronary angiography is associated with a low rate of ischemic and bleeding events at 30 days. PMID: 30012889 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - July 18, 2018 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Orbital Atherectomy of Severely Calcified Unprotected Left Main Coronary Artery Disease: One-Year Outcomes.
CONCLUSION: Orbital atherectomy is an acceptable treatment option for patients with severely calcified ULMCA disease, especially if patients are deemed too high risk for surgical revascularization. PMID: 29958177 [PubMed - in process]
Source: The Journal of Invasive Cardiology - July 1, 2018 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

One-Year Outcomes of Orbital Atherectomy of Long, Diffusely Calcified Coronary Artery Lesions.
CONCLUSIONS: Despite the higher angiographic complication rates, orbital atherectomy of long, diffusely calcified lesions was associated with acceptable rates of ischemic complications in this challenging lesion subset at 1-year follow-up. PMID: 29799426 [PubMed - in process]
Source: The Journal of Invasive Cardiology - May 29, 2018 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Multicenter Registry of Real-World Patients With Severely Calcified Coronary Lesions Undergoing Orbital Atherectomy: 1-Year Outcomes.
CONCLUSION: Orbital atherectomy is a valuable option for the treatment of severely calcified coronary arteries, including patients with very complex coronary anatomy and severe underlying comorbid conditions. Orbital atherectomy provided acceptable outcomes at 1 year and compared favorably to historical controls. A randomized trial with longer follow-up is needed to determine the optimal treatment strategy for patients with severely calcified coronary lesions. PMID: 29610442 [PubMed - in process]
Source: The Journal of Invasive Cardiology - April 5, 2018 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Impact of the Use of Intravascular Imaging on Patients Who Underwent Orbital Atherectomy.
CONCLUSION: Orbital atherectomy guided by intravascular imaging is feasible and safe. A large prospective randomized trial is needed to determine the clinical benefit of IVUS/OCT during PCI with orbital atherectomy. PMID: 29378972 [PubMed - in process]
Source: The Journal of Invasive Cardiology - January 31, 2018 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Comparison of Heparin and Bivalirudin in Patients Undergoing Orbital Atherectomy.
CONCLUSION: Both heparin and bivalirudin were safe and effective antithrombotic agents for patients who underwent orbital atherectomy. A randomized trial is needed to determine the antithrombotic agent of choice for orbital atherectomy. PMID: 29086730 [PubMed - in process]
Source: The Journal of Invasive Cardiology - November 2, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Outcomes of Patients With a History of Coronary Artery Bypass Grafting Who Underwent Orbital Atherectomy for Severe Coronary Artery Calcification.
CONCLUSION: Despite a higher-risk baseline profile, patients with a history of CABG had similar angiographic and clinical outcomes compared with patients who had no previous history of CABG. Further studies are needed to clarify the role of orbital atherectomy in these patients. PMID: 28974662 [PubMed - in process]
Source: The Journal of Invasive Cardiology - October 6, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

"Single-Operator" Technique for Advancing the Orbital Atherectomy Device.
CONCLUSION: The single-operator technique is feasible, can be used to maintain wire position while the OA device is advanced, and obviates the need for a skilled assistant when advancing the OA device. PMID: 28255104 [PubMed - in process]
Source: The Journal of Invasive Cardiology - March 5, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

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