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Predictive Model for PICC Occlusion Risk for Patients in Intensive Care Units: A Retrospective Clinical Study
CONCLUSIONS: Age ≥65 years, BMI ≥24 kg/m2, diabetes, malignant tumors, blood transfusions, and intravenous nutrition were independent risk factors for PICC occlusion, while the frequency of flushing and sealing pipe (Q8h) was a protective factor. This prediction model had an outstanding ability to discriminate in identifying patients with a high-risk of PICC occlusion in the ICU.PMID:37573601
Source: Alternative Therapies in Health and Medicine - August 13, 2023 Category: Complementary Medicine Authors: Yijun Zhu Diwen Li Yunfei Li Weiwei Cai Source Type: research

Challenge to the Intestinal Mucosa During Sepsis
Conclusion The impact of sepsis on the gut is manifold, e.g., sepsis mediated alteration of the gut-blood barrier and increase in the intestinal permeability, which may correlate with the phenomena of bacterial translocation and lymphatic activation (“toxic-lymph”). Systemic consequences of sepsis are widespread and concern to the coagulative system, the microbiome as well as enzymes, such as pancreatic proteases, MMPs and IAPs. Nevertheless, the therapeutic approaches for modulating the mucosal immune system are still rarely effective in daily routine. Recent published studies showing that treatment with ...
Source: Frontiers in Immunology - April 29, 2019 Category: Allergy & Immunology Source Type: research