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Botany, traditional uses, phytochemistry, pharmacology and toxicology of Ilex pubescens Hook et Arn
ConclusionsThis review summarizes the results from current studies of I. pubescens, which is one of the valuable medicinal sources from traditional herbs. Some conventional uses have been evaluated by pharmacological investigation. In addition, unresolved issues include molecular mechanisms underlying bioactivities, pharmacokinetics, toxicology and efficacy, which are still being studied and explored before achieving integration into clinical medicines.
Source: Journal of Ethnopharmacology - August 9, 2019 Category: Drugs & Pharmacology Source Type: research

Salvia miltiorrhiza Bunge (Danshen) extract attenuates permanent cerebral ischemia through inhibiting platelet activation in rats
Conclusions SCED attenuates cerebral ischemic injury. The possible mechanism is that SCED inhibits thrombosis formation, platelet aggregation and activation of PLC/PKC pathway. On this basis, this new extract could be a promising agent to inhibit thrombosis formation and protect against cerebral ischemia injury. Graphical abstract
Source: Journal of Ethnopharmacology - June 21, 2017 Category: Drugs & Pharmacology Source Type: research

Anti-platelet and anti-thrombotic effect of a traditional herbal medicine Kyung-Ok-Ko
Conclusions These findings suggest that KOK elicits remarkable anti-platelet and anti-thrombotic effects with less side effect of bleeding, and therefore, it may have a therapeutic potential for the prevention of platelet-associated cardiovascular diseases. Graphical abstract
Source: Journal of Ethnopharmacology - December 17, 2015 Category: Drugs & Pharmacology Source Type: research