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Diagnosis, Management, and Pathophysiology of Arterial and Venous Thrombosis in COVID-19
This JAMA Insights review summarizes the pathophysiology underlying the thrombotic diathesis characteristic of acute SARS-CoV-2 infection and current recommendations for the prevention, diagnosis, and management of the most common thrombotic complications in COVID-19, including acute myocardial infarction (AMI), ischemic stroke, and venous thromboembolism (VTE).
Source: JAMA - Journal of the American Medical Association - November 23, 2020 Category: General Medicine Source Type: research

CHA 2 DS 2 -VASc Accuracy for Predicting Heart Failure Outcomes
This cohort study assessed the accuracy of the CHA2DS2-VASc score for predicting ischemic stroke, thromboembolism, and death in patients with heart failure with and without atrial fibrillation.
Source: JAMA - Journal of the American Medical Association - August 30, 2015 Category: Journals (General) Source Type: research

Bivalirudin vs Heparin With or Without Tirofiban During Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction The BRIGHT Randomized Clinical Trial
ImportanceThe safety and efficacy of bivalirudin compared with heparin with or without glycoprotein IIb/IIIa inhibitors in patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PCI) are uncertain.ObjectiveTo determine if bivalirudin is superior to heparin alone and to heparin plus tirofiban during primary PCI.Design, Setting, and ParticipantsMulticenter, open-label trial involving 2194 patients with AMI undergoing primary PCI at 82 centers in China between August 2012 and June 2013.InterventionsPatients were randomly assigned to receive bivalirudin with a post-PCI infusion (...
Source: JAMA - Journal of the American Medical Association - March 16, 2015 Category: Journals (General) Source Type: research

The Case Files: Unusual Headache
By Al-Hashimi, Siddhartha DO; Leavens, John MD A 23-year-old woman with a history of migraine headaches presented to the emergency department for a different-than-usual headache. She had a six-day history of intermittent headaches. The onset was at rest, and there was no history of trauma.   The headache was located behind her left eye, and it radiated into the posterior portion of her head. She characterized it as being 8/10 in intensity. Bright lights were reported as an exacerbating factor. The headache was associated with nausea and multiple episodes of emesis. She had 10 episodes of vomiting the evening prior to arri...
Source: The Case Files - June 5, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Speed Vital For Stroke Patients' Survival
The sooner stroke patients receive thrombolytic treatment, the lower their risk of in-hospital mortality and intracranial hemorrhage, says a new study published in JAMA (Journal of the American Medical Association). In addition, the prompter the treatment, the higher the rate of walking ability at discharge. Intravenous (IV) tissue-type plasminogen activator (tPA) is a form of treatment proven to help stroke patients within 4.5 hours of onset of symptoms...
Source: Health News from Medical News Today - June 19, 2013 Category: Consumer Health News Tags: Stroke Source Type: news