• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Meta-Analysis Comparing Direct Oral Anticoagulants to Vitamin K Antagonists for The Management of Left Ventricular Thrombus
Expert Rev Cardiovasc Ther. 2021 Apr 8. doi: 10.1080/14779072.2021.1915134. Online ahead of print.ABSTRACTINTRODUCTION: To compare vitamin K antagonist (VKAs) and direct oral anticoagulants (DOACs) treatment in patients with left ventricular (LV) thrombus. The primary outcome was stroke or systemic embolism (SSE). Secondary outcomes were thrombus resolution, bleeding, and death.AREAS COVERED: Five observational studies were included (total n=700; VKAs n = 480; DOACs n = 220). There was a trend toward less SSE with VKAs compared to DOACs (5.2% vs. 9%; OR = 0.54, 95% CI= 0.29-1.01, p = 0.05). No significant difference betwee...
Source: Expert Review of Cardiovascular Therapy - April 8, 2021 Category: Cardiology Authors: Hesham K Abdelaziz Michael Megaly Maciej Debski Amr Abdelrahman Shehab Abdelaziz Diaa Kamal Billal Patel Ranjit More Tawfiq Choudhury Source Type: research

Triple antithrombotic therapy in patients with atrial fibrillation undergoing PCI: Current evidence and practice.
Authors: Clarke A, Ibrahim A, Kiernan TJ Abstract INTRODUCTION: Patients with atrial fibrillation taking oral anticoagulation and undergoing percutaneous coronary intervention with stent insertion are recommended to receive antithrombotic therapy with aspirin and P2Y12 receptor antagonist. This combinatory regime encompasses triple therapy (TT). Although TT reduces the risk of ischaemic events such as stroke and stent thrombosis, it is associated with an increased bleeding risk. Areas covered: The efficacy and safety profile of TT is uncertain with undetermined optimal duration and therapeutic combination. This rev...
Source: Expert Review of Cardiovascular Therapy - September 16, 2018 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research