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Aspirin Alone Is Superior Therapy for Grade III Blunt Carotid Injury: A Multicenter Study from the Eastern Association for the Surgery of Trauma
The optimal treatment of blunt cerebrovascular injury (BCVI) remains unclear. Antiplatelet therapy and therapeutic anticoagulation have each demonstrated substantial reductions in BCVI-associated stroke without evidence of the superiority of either. Uncertainty surrounds grade III injury, in particular, because stroke can involve both platelet activation from endothelial injury and thrombus formation within the pseudoaneurysm sac. We hypothesized that treatment of grade III blunt carotid injury (BCI) with aspirin alone would be associated with a decreased rate of subsequent stroke compared with other medical therapies.
Source: Journal of Vascular Surgery - August 24, 2021 Category: Surgery Authors: Rishi Kundi, Emily C. Esposito, Thomas M. Scalea, Deborah M. Stein, Margaret Lauerman, East Blunt Cerebrovascular Injury Study Group Tags: S3: Plenary Session 3 Source Type: research

Management of common carotid artery dissection due to extension from acute type A (DeBakey I) aortic dissection
Conclusions: CCAD, due to extension from aortic arch dissection, has a low risk of subsequent stroke after the initial event. Based on current data, there is little evidence to suggest that aortic origin CCAD requires repair in the absence of recurrent symptoms, regardless of the degree of stenosis or false-lumen patency. Recommended optimal medical therapy includes either aspirin or anticoagulation for 6 months after initial presentation. Additional longitudinal studies are needed.
Source: Journal of Vascular Surgery - May 13, 2013 Category: Surgery Authors: Kristofer M. Charlton-Ouw, Ali Azizzadeh, Harleen K. Sandhu, Ali Sawal, Samuel S. Leake, Charles C. Miller, Anthony L. Estrera, Hazim J. Safi Tags: Clinical research studies Source Type: research